Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Emergency C-section may compromise development and long-term health of babies

Labor and natural childbirth causes stress on a mother’s body but an emergency Caesarean is associated with even more inflammatory gene expression in the placenta, new South Australian research shows.

6 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

A recent study observed that the replication of the SARS-CoV-2 Omicron variant was restricted in human lung tissues

5 Apr 2022

Prior COVID vaccination induces a more robust antibody response to Omicron

A recent study posted to the medRxiv* preprint server assessed the impact of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination on the human immune response against SARS-CoV-2 Omicron infection.

5 Apr 2022

Animal study provides insights into how COVID-19 can lead to long-term pain

A new animal study has provided important insights into how COVID-19 SARS-CoV-2 - the virus responsible for COVID-19 - can lead to long-term pain.

4 Apr 2022

Study offers insights into the long-term impacts of weight-loss diets and food insecurity

Could fluctuations in body weight resulting from drastically cutting and increasing calories lead to physiological changes that raise the risk of heart disease or diabetes later in life?

1 Apr 2022

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

31 Mar 2022

Research provides a roadmap for new therapies to treat chorioamnionitis

One of the serious complications that can occur during late pregnancy happens when the amniotic sac (also called the bag of waters) breaks too early, which can allow bacterial infections to cause dangerous tissue inflammation around the placenta.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

ProteoGenix, a contract research organization specialized in biologics discovery and bioproduction, announces the launch of its XtenCHOTM Transient Expression System.

From ProteoGenix 30 Mar 2022

$4 million program launched to find transformative therapies for ADNP syndrome

Researchers at the UC Davis MIND Institute are launching a $4 million program to find transformative therapies for ADNP syndrome. The rare genetic condition causes developmental delays and can affect the brain, heart, gastrointestinal system and more.

29 Mar 2022

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

Similar to a light switch, RNA switches (called riboswitches) determine which genes turn "on" and "off." Although this may seem like a simple process, the inner workings of these switches have confounded biologists for decades.

29 Mar 2022

Genetic risk for asthma may be mediated through altered gene expression in the airway cells

A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium.

28 Mar 2022

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers discuss alternate therapeutic targets for treating COVID-19 and the effects of Gal-9 on SARS-CoV-2 infection and the immune response.

23 Mar 2022

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's Disease and Related Dementias.

23 Mar 2022

Importance of Numb-associated kinases in SARS-CoV-2 infection

A new study posted to the bioRxiv* preprint server has focussed on assessing four members of the NAK family that are associated with SARS-CoV-2 infection. These kininases could act as a target for the development of effective COVID-19 therapeutics.

23 Mar 2022

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

A human immune system is a lot like the board game Mouse Trap: it's a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub - which, in turn, springs a trap on some plastic mice - proteins trigger other proteins to activate immune cells and direct them toward germs.

22 Mar 2022

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Researchers performed an in situ analysis to evaluate the correlation between CD48 expression and COVID-19.

22 Mar 2022

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

The findings of a new study suggest that a ketogenic diet - which is low in carbohydrates and protein, but high in fat - helps to kill pancreatic cancer cells when combined with a triple-drug therapy developed by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

22 Mar 2022

Gene Expression News and Research

Further Reading

Emergency C-section may compromise development and long-term health of babies

Phenotypic changes in monocytes from COVID-19 patients

Study investigates the local-mucosal susceptibility and innate immune response to Omicron compared to other variants

Prior COVID vaccination induces a more robust antibody response to Omicron

Animal study provides insights into how COVID-19 can lead to long-term pain

Study offers insights into the long-term impacts of weight-loss diets and food insecurity

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Research provides a roadmap for new therapies to treat chorioamnionitis

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

$4 million program launched to find transformative therapies for ADNP syndrome

Strand displacement mechanism in RNA appears to switch genetic expression from “on” to “off”

Genetic risk for asthma may be mediated through altered gene expression in the airway cells

Researchers investigate Galectin-9 as a new treatment target for COVID-19

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

Importance of Numb-associated kinases in SARS-CoV-2 infection

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

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