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Portable MRI and AI improve Alzheimer’s diagnosis with cost-effective precision

Researchers optimized portable low-field MRI with machine learning to improve brain morphometry and white matter hyperintensity detection, making Alzheimer's diagnosis more accessible and cost-effective.

12 Dec 2024

Key to LDL clearance uncovered: Structural details of apoB100-LDLR binding emerge

Researchers reveal the structural details of apoB100's interaction with LDL receptors, offering insights into LDL dimerization and potential treatments for familial hypercholesterolemia.

12 Dec 2024

Metabolomic biomarkers improve diabetes risk prediction accuracy

Researchers developed a novel diabetes risk score integrating traditional factors with metabolomic biomarkers, achieving improved prediction accuracy for 10-year type 2 diabetes risk.

12 Dec 2024

Fatty acids disrupt glutamate transporter function in brain cells

Glutamate transporters pump glutamate from the synaptic cleft back into brain cells after its release during neurotransmission.

12 Dec 2024

PROSPECT-Lung trial aims to improve treatment for patients with resectable non-small cell lung cancer

The highly anticipated PROSPECT-Lung trial has officially opened, marking a significant step forward in the quest to improve treatment strategies for patients with resectable non-small cell lung cancer.

11 Dec 2024

New technique enables laser light to penetrate deeper into living tissues

Metabolic imaging is a noninvasive method that enables clinicians and scientists to study living cells using laser light, which can help them assess disease progression and treatment responses.

11 Dec 2024

Penn-led consortium to advance imaging of brain diseases

A Penn Medicine-led consortium of radiology and chemistry researchers across the United States will advance imaging of diseases like Parkinson's by testing radiotracers they identified that illuminate α-synuclein (αSyn) or 4R tau proteins on positron emission tomography (PET) scans.

11 Dec 2024

Early smoking causes structural and functional heart damage

Cigarette smoking from childhood into early adulthood is associated with an increased risk of premature cardiac injury, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

11 Dec 2024

Caltech develops microrobots for precise drug delivery

In the future, delivering therapeutic drugs exactly where they are needed within the body could be the task of miniature robots. Not little metal humanoid or even bio-mimicking robots; think instead of tiny bubble-like spheres.

11 Dec 2024

High-dose chemotherapy followed by autologous stem cell transplant ineffective for patients with mantle cell lymphoma

Late-breaking research reveals there is no benefit from high-dose chemotherapy followed by autologous stem cell transplant (ASCT) for patients with mantle cell lymphoma (MCL) in remission following their initial treatment.

11 Dec 2024

Early exposure to parental smoking linked to higher MS risk

Cutting early life exposure to parental smoking may lower the risk of developing MS (multiple sclerosis) in those who are genetically predisposed to the disease, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Dec 2024

Researchers explore patient's perceptions of AI in radiology

AI-powered MRIs could cut the potentially toxic dyes used in traditional MRIs by up to 80 percent, but will patients embrace AI-driven brain scans?

10 Dec 2024

Key plasma proteins signal critical periods in brain aging

Researchers identified 13 plasma proteins linked to brain aging, uncovering dynamic patterns and biomarkers for early intervention in aging-related brain health.

10 Dec 2024

Metabolic imaging detects ovarian cancer subtypes and predicts chemotherapy response

Study demonstrates how metabolic imaging differentiates high and low oxidative phosphorylation (OXPHOS) subtypes of high-grade serous ovarian cancer (HGSOC). By assessing metabolic activity, it also identifies early and variable responses to chemotherapy, improving precision in treatment strategies.

10 Dec 2024

Structural and functional brain changes found in individuals with opioid use disorder

Researchers at the Yale School of Medicine found structural and functional alterations in specific brain regions of individuals with opioid use disorder.

10 Dec 2024

Study finds key brain markers for gaming addiction in adolescents

Playing video games is a rite of passage for many adolescents, but for some, it could also be the first step to a gaming addiction.

10 Dec 2024

Researchers find brain-body immune link in the dural sinuses and skull marrow

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London provides valuable insights into the brain-body immune connection identifying key communication hubs in the dural sinuses and skull bone marrow at the back of the head.

10 Dec 2024

New triplet therapies show promise for relapsed and newly diagnosed leukemias

Three clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated significant positive results from novel triplet therapies in the treatment of relapsed or refractory and newly diagnosed leukemias.

9 Dec 2024

Tea, apples, and chocolate proven to support liver health

A flavonoid-rich diet, including apples, tea, and dark chocolate, significantly lowers the risk of non-alcoholic fatty liver disease (NAFLD) and improves liver health biomarkers. These findings highlight the potential of dietary flavonoids in combating liver fat accumulation and inflammation.

9 Dec 2024

UVM scientists discover new mechanism for blood flow regulation in the brain

A team of UVM scientists led by Mark Nelson, Ph.D., from the Larner College of Medicine at the University of Vermont, has uncovered a novel mechanism that reshapes our understanding of how blood flow is regulated in the brain.

9 Dec 2024