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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Omics analysis identifies new biomarkers for predicting mortality in patients with pneumonia

Community-acquired pneumonia (CAP) is a major infectious disease worldwide and contributes to high mortality and massive economic burden. Hospital mortality among the severe CAP (SCAP) remains high, ranging from 25% to more than 50%.

22 Sep 2023

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Researchers from the Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health have made an important finding about Aedes aegypti mosquitoes - one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.

22 Sep 2023

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Researchers proposed a simplified approach for analyzing mRNA vaccines using long-read sequencing.

22 Sep 2023

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.

22 Sep 2023

Multipronged gene therapy restores walking in mice after complete spinal cord injury

When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

A study has revealed new details about a key population of immune system cells critical to successful vaccination against the pandemic virus, SARS-CoV-2.

21 Sep 2023

Scientists identify key proteins that regulate organ laterality

In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell.

21 Sep 2023

Rice engineers develop split gene-editing tool with enhanced control

To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third small molecule is added.

21 Sep 2023

New CAR T cell therapy approach minimizes severe side effects

In recent years, cancer researchers have hailed the arrival of chimeric antigen receptor T cell (CAR T) therapy, which has delivered promising results, transforming the fight against various forms of cancer. The process involves modifying patients' T-cells to target cancer cells, resulting in remarkable success rates for previously intractable forms of cancer.

19 Sep 2023

Gaining new insights into neurological diseases by studying circular RNAs in brain cells

Researchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells.

19 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

MGI partners with National Cancer Centre Singapore to undergo comprehensive genomic profiling of Asian-Prevalent cancers

MGI Tech Singapore Pte, Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, recently entered a research partnership with National Cancer Centre Singapore ("NCCS") to facilitate comprehensive, multi-dimensional genomic profiling of Asian-prevalent cancers using MGI's core DNBSEQ™ technology.

From MGI 18 Sep 2023

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate.

18 Sep 2023

Polish gulls harbor new coronavirus strains, spotlighting avian role in viral evolution

Researchers in Poland have identified five strains of gammacoronaviruses and deltacoronaviruses in black-headed and common gulls, shedding new light on the diversity and evolutionary potential of these viruses. The study highlights the need for ongoing research into animal reservoirs of coronaviruses, as they pose a risk for zoonotic transmission to humans.

17 Sep 2023

Using sea slug brains to map human brain development

A University of Massachusetts Amherst neuroscientist has been awarded a $3.1 million grant from the National Institute of Neurological Disease and Stroke to advance knowledge on human brain development by using an unusual subject: the brain of the sea slug.

15 Sep 2023

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Shared genetic markers and immune system involvement in sJRA and T1D.

15 Sep 2023

Multi-omics study offers insights into psoriasis treatment

Researchers use a multi-omics approach combining immune cell-enriched scRNA-seq, microarray analysis, and immunohistochemistry to elucidate the translational role of anti-IL-17A in suppressing the autoimmune functions of T17 cells, thereby effectively treating human psoriasis.

14 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

RNA News and Research

Further Reading

Omics analysis identifies new biomarkers for predicting mortality in patients with pneumonia

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Multipronged gene therapy restores walking in mice after complete spinal cord injury

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

Scientists identify key proteins that regulate organ laterality

Rice engineers develop split gene-editing tool with enhanced control

New CAR T cell therapy approach minimizes severe side effects

Gaining new insights into neurological diseases by studying circular RNAs in brain cells

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Single-cell screening of cerebral organoids to identify developmental defects in autism

MGI partners with National Cancer Centre Singapore to undergo comprehensive genomic profiling of Asian-Prevalent cancers

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Polish gulls harbor new coronavirus strains, spotlighting avian role in viral evolution

Using sea slug brains to map human brain development

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Multi-omics study offers insights into psoriasis treatment

Reviving reservoirs: new findings shake up HIV treatment understanding

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