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Transplanted human stool may offer treatment hope for ulcerative colitis patients

Patients with ulcerative colitis (UC) may improve their symptoms with a transplantation of healthy stool from donors, according to Australian researchers. The findings were presented by Dr Sudarchan Paramsothy MD, a gastroenterologist from the University of New South Wales, Australia at the Digestive Disease Week conference in San Diego, California between the 21st to 24th May.

24 May 2016

Could whole-mount scanning of breast tissue lead to better clinical outcomes? An interview with Dr Martin Yaffe

We actually normally refer to this as whole-specimen imaging of breast tissue.

From Huron Technologies 24 May 2016

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Only 12% of kidney cancer patients with advanced disease survive five years after their initial treatment. In a Roswell Park Cancer Institute-led study, scientists report that some patients with advanced kidney cancer who continued to receive a novel immunotherapy drug after their disease progressed saw clinical benefit.

24 May 2016

Aliskiren fails to show benefit for heart failure patients with diabetes

A subgroup analysis in heart failure patients with diabetes from the ATMOSPHERE trial has failed to show benefit and signals the end of the road for aliskiren in heart failure.

24 May 2016

Scientists find ketamine as effective sedative for treating highly-agitated patients prior to hospitalisation

Scientists have shown that ketamine is far more effective than the more commonly used haloperidol for treating highly-agitated patients prior to hospitalisation.

23 May 2016

JBCPP journal publishes new evidence for clinical efficacy of cannabis therapy

New evidence for the clinical efficacy of cannabis therapy is presented in the latest issue of the Journal of Basic and Clinical Physiology and Pharmacology, a De Gruyter publication.

23 May 2016

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Two new studies raise enough questions about a possible link between childhood cancer and light therapy for newborn jaundice that clinicians should exercise caution in prescribing the treatment for infants whose jaundice is likely to resolve on its own, a pediatric oncologist from Dana-Farber/Boston Children's Cancer and Blood Disorders Center argues in an editorial published today by the journal Pediatrics.

23 May 2016

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.

23 May 2016

Researchers developing web-based, decision-support tool for osteoarthritis patients

Researchers at UMass Medical School are developing a web-based, decision-support tool for osteoarthritis patients that will provide individualized, evidence-based information in real time to guide optimal knee and hip care, including joint replacement.

23 May 2016

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

A team of researchers from Cornell University in Ithaca, New York demonstrated a drug delivery mechanism that utilizes two independent vehicles, allowing for delivery of chemically and physically dis-tinct agents.

23 May 2016

New computational model simulates long-term effects of cardiac regenerative therapies

Heart failure (HF) continues to pose a significant burden on our society. One of the most common heart diseases is myocardial infarction (MI), which results in a permanent loss of contractile function in the infarcted region.

23 May 2016

Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

A research team from Spain has prepared a Cochrane systematic review that explores the efficacy, safety, and adherence to fixed-dose combinations (FDCs) of drugs versus single-drug formulations to treat people who are newly diagnosed with tuberculosis (TB).

23 May 2016

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications.

22 May 2016

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Intensive therapies to reduce high blood pressure can cut the risk of heart disease in older adults without increasing the risk for falls, according to doctors at Wake Forest Baptist Medical Center.

21 May 2016

Researchers urge specific guidelines for fertility, sexual function counseling in at-risk pediatric patients

The drugs and therapies used to treat medical conditions often come with side effects. Doctors, pharmacists and other health care professionals strive to be sure we are made aware.

20 May 2016

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will provide an update on their extensive oncology pipeline at the annual meeting of the American Society of Clinical Oncology in Chicago, USA, on 3-7 June 2016.

20 May 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Coprophagia linked to neurodegenerative dementia

Coprophagia, eating one's feces, is common in animals but rarely seen in humans. Mayo Clinic researchers reviewed the cases of a dozen adult patients diagnosed with coprophagia over the past 20 years and found that the behavior is associated with a wide range of neuropsychiatric disorders, particularly neurodegenerative dementias.

20 May 2016

Therapy News and Research

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Could whole-mount scanning of breast tissue lead to better clinical outcomes? An interview with Dr Martin Yaffe

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Aliskiren fails to show benefit for heart failure patients with diabetes

Scientists find ketamine as effective sedative for treating highly-agitated patients prior to hospitalisation

JBCPP journal publishes new evidence for clinical efficacy of cannabis therapy

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Researchers developing web-based, decision-support tool for osteoarthritis patients

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

New computational model simulates long-term effects of cardiac regenerative therapies

Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Researchers urge specific guidelines for fertility, sexual function counseling in at-risk pediatric patients

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

New frozen faecal bank increases chances of curing a chronic health condition

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Coprophagia linked to neurodegenerative dementia

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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