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Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structures.

14 Jul 2016

Study shows spinal cord stimulation can be safe, effective treatment option for chronic pain sufferers

Chronic pain affects up to 20% of people in developed countries, and represents not only a profound impact on individuals and their families but also a sizeable burden on employers, health care systems, and society in general.

14 Jul 2016

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Hospital-acquired pneumonia and ventilator-associated pneumonia– which account for 20 to 25 percent of hospital-acquired infections – should be treated with shorter courses of antibiotics than they typically are, according to new guidelines released by the Infectious Diseases Society of America and American Thoracic Society and published in the journal Clinical Infectious Diseases.

14 Jul 2016

Researchers discover strong genetic risk factor for IgA nephropathy

An international research collaboration has discovered a strong genetic risk factor for IgA nephropathy (IgAN) - the most common inflammatory kidney disease worldwide - and related renal dysfunction.

14 Jul 2016

VIB research reveals new insights into ALS

Research into amyotrophic lateral sclerosis (ALS) conducted by VIB-KU Leuven has led to interesting and unexpected conclusions.

14 Jul 2016

Researchers identify new drug target for treating children with CNS-PNET

Primitive neuroectodermal tumors (PNETs) are the largest group of malignant brain tumors in children. They can arise from the brain's cerebellum or, more rarely, from tissue located throughout the central nervous system (CNS).

14 Jul 2016

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Cancer remains a leading cause of death worldwide, and the global cancer burden is expected to increase by 70 percent over the next two decades.

14 Jul 2016

Study finds low rates of baseline BMD testing among older women with breast cancer

Aromatase inhibitors (AIs)—drugs that stop the production of estrogen in women—are standard adjuvant therapy for post-menopausal women with hormone-receptor positive breast cancer.

14 Jul 2016

Study identifies specific characteristics that predispose women to different hot flashes, night sweat patterns

Most women will get hot flashes or night sweats at some point in life. However, when these symptoms occur and how long they last can vary dramatically among women.

14 Jul 2016

Study finds evidence that PD-1 antibody may benefit men with metastatic prostate cancer

Restoring tumor-specific immunity is a treatment strategy that works well in melanoma and lung cancer patients. Now a new study out of the OHSU Knight Cancer Institute is reviving hope that the approach also may help men with life-threatening prostate cancer.

14 Jul 2016

Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

14 Jul 2016

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Older adults with chronic obstructive pulmonary disease who start using opioids have a more than two-fold higher risk of dying from a respiratory-related complication compared to non-opioid users, St. Michael's Hospital researchers have found.

14 Jul 2016

AAPS Foundation announces winner of 2016 New Investigator Grant

The AAPS Foundation is pleased to announce the 2016 New Investigator Grant recipient, Yizhou Dong, Ph.D of the Ohio State University, for his research entitled "Development of nonviral gene-engineering delivery systems".

14 Jul 2016

New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

The Wistar Institute is pleased to announce that the National Institutes of Health has awarded a nearly $23 million Martin Delaney Collaboratories for HIV Cure Research grant to the BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy, a consortium of top HIV researchers led by co-principal investigators Luis J. Montaner, D.V.M., D.Phil., director of the HIV-1 Immunopathogenesis Laboratory at The Wistar Institute Vaccine Center, and James L. Riley, Ph.D., research associate professor at the Perelman School of Medicine at the University of Pennsylvania.

13 Jul 2016

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

A Houston Methodist research team received a nearly $4 million grant to test a transcutaneously refillable implant that administers pre-exposure prophylaxis drugs to subjects at risk of HIV-exposure.

13 Jul 2016

Community-level ART coverage, male circumcision linked to decline in new male HIV infections in Uganda

Increasing the number of men who undergo circumcision and increasing the rates at which women with HIV are given antiretroviral therapy (ART) were associated with significant declines in the number of new male HIV infections in rural Ugandan communities, new Johns Hopkins Bloomberg School of Health research suggests.

13 Jul 2016

Sugar-binding protein galectin-9 could be new weapon to fight HIV

The ultimate impediment to a cure for HIV infection is the presence of latent, HIV-infected cells, which can reawaken and produce new virus when antiretroviral drug therapy is stopped.

13 Jul 2016

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose and insulin levels. That's why a recent discovery made by Rudy Valentine and a team of researchers holds so much promise.

13 Jul 2016

Italian researchers identify new variant of emerging antibiotic resistance mechanism

A team of Italian investigators has discovered a new variant of an emerging antibiotic resistance mechanism. The new variant, dubbed mcr-1.2, confers resistance to colistin, a last-resort antibiotic against multidrug-resistant Gram-negative pathogens.

13 Jul 2016

Therapy News and Research

Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

Study shows spinal cord stimulation can be safe, effective treatment option for chronic pain sufferers

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Researchers discover strong genetic risk factor for IgA nephropathy

VIB research reveals new insights into ALS

Researchers identify new drug target for treating children with CNS-PNET

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Study finds low rates of baseline BMD testing among older women with breast cancer

Study identifies specific characteristics that predispose women to different hot flashes, night sweat patterns

Study finds evidence that PD-1 antibody may benefit men with metastatic prostate cancer

Penn study provides more insights into cardiovascular side effects of breast cancer drug

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

AAPS Foundation announces winner of 2016 New Investigator Grant

New treatment approach may benefit relapsed post-transplant blood cancer patients

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

Community-level ART coverage, male circumcision linked to decline in new male HIV infections in Uganda

Sugar-binding protein galectin-9 could be new weapon to fight HIV

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Italian researchers identify new variant of emerging antibiotic resistance mechanism

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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