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Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals.

20 May 2016

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.

19 May 2016

New autism classification system defines social communication ability levels among ASD children

Children with autism have a wide range of ability to talk with other people, but it has been difficult to group children by their specific skills.

19 May 2016

Nanoparticle-based gene therapy may hold promise for patients with asthma

A new study has demonstrated a way to deliver a nanoparticle-based gene therapy, in order to repair lungs damaged by chronic allergic asthma and to reduce inflammation that causes asthma attacks.

19 May 2016

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression.

19 May 2016

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Patients with Middle East Respiratory Syndrome (MERS) develop more severe critical illness and have higher mortality than patients with non-MERS severe acute respiratory infection (SARI), according to investigators involved with the largest study of critically ill patients with MERS.

19 May 2016

Penn State researchers link mutation in common virus to fatal brain disease

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.

19 May 2016

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Endometrial cancer is the most common gynecologic cancer in the U.S. Most cases are diagnosed at early stage and have good prognosis. Unfortunately, some patients with early stage and low grade endometrial cancer experience recurrence - and the reasons are not entirely clear.

19 May 2016

Experts find vast mental health treatment gap in China and India

A third of the global burden of disease for mental, neurological and substance use disorders occurs in India and China – more than in all high-income countries combined – yet most people with mental disorders in these countries do not receive needed treatment.

19 May 2016

New Quick Reference Guide set to improve antibiotic prescribing

A Tasmanian initiative to provide a ‘Quick Reference Guide’ to antibiotic prescribing in the community has been embraced by general practitioners (GPs) and is set to improve prescribing, delegates at the National Medicines Symposium in Canberra have heard.

19 May 2016

Clinicians perform UK’s first MRI-guided focused ultrasound treatment for prostate cancer

INSIGHTEC congratulates the medical team at Imperial College Healthcare NHS Trust for performing the first MR-guided focused ultrasound treatment in the United Kingdom for prostate cancer.

19 May 2016

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica.

19 May 2016

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response.

19 May 2016

Tecentriq drug gets FDA approval to treat urothelial carcinoma

The U.S. Food and Drug Administration today approved Tecentriq (atezolizumab) to treat the most common type of bladder cancer, called urothelial carcinoma. This is the first product in its class (PD-1/PD-L1 inhibitors) approved to treat this type of cancer.

19 May 2016

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

A new study shows that repeated radiation therapy used to target tumors in the brain may not be as safe to healthy brain cells as previously assumed.

19 May 2016

Play-based procedural preparation helps reduce sedation use and costs tied to cranial radiation therapy

New research from St. Jude Children's Research Hospital shows support interventions by child life specialists decrease sedation use and costs associated with cranial radiation therapy.

19 May 2016

AHA/ASA targets acute ischemic stroke guidelines

Acute Ischemic Stroke Guidelines are the subject of a new toolkit from the American Heart Association/American Stroke Association aimed at accelerating adoption of the 2015 update regarding endovascular treatment.

19 May 2016

$Allogeneic HSCT offers good survival for select TKI-refractory CML patients$

Therapy News and Research

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

New autism classification system defines social communication ability levels among ASD children

Nanoparticle-based gene therapy may hold promise for patients with asthma

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Penn State researchers link mutation in common virus to fatal brain disease

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Experts find vast mental health treatment gap in China and India

New Quick Reference Guide set to improve antibiotic prescribing

Clinicians perform UK’s first MRI-guided focused ultrasound treatment for prostate cancer

Natural product darwinolide may help combat fatal MRSA infection

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

Tecentriq drug gets FDA approval to treat urothelial carcinoma

Conventional repeated radiation treatments may offer no major benefit to brain tumor patients

Play-based procedural preparation helps reduce sedation use and costs tied to cranial radiation therapy

AHA/ASA targets acute ischemic stroke guidelines

Allogeneic HSCT offers good survival for select TKI-refractory CML patients

Real-world CML management in line with ELN guidelines

Antihypertensive initiation, intensification linked to raised short-term fall risk

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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