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Harnessing nanomaterials to induce ferroptosis in cancer treatment

Announcing a new publication for Acta Materia Medica journal. Tumor ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has emerged as a promising therapeutic strategy for combating cancers, particularly in cases involving cancer stem cells (CSCs) and drug resistance.

15 May 2025

HIV vaccine study marks breakthrough in targeting broad immune responses

A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus.

15 May 2025

Breakthrough bat organoid platform sheds light on behavior of zoonotic viruses

Did you know that more than 75% of new infectious diseases affecting humans originally come from animals? Bats, in particular, are natural hosts to some of the world's most dangerous viruses, including those responsible for COVID-19 (SARS-CoV-2), MERS-CoV, influenza A, and hantavirus outbreaks.

15 May 2025

Researchers identify key cells behind peanut allergy prevention

A decade ago, a clinical trial in the U.K. famously showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts.

15 May 2025

Study finds fewer H. pylori infections among Parkinson’s patients

A large case-control study from China found that people with Parkinson’s disease were significantly less likely to test positive for Helicobacter pylori infection compared to controls. The findings suggest a potential protective link between this common stomach bacterium and Parkinson’s disease, though causality remains unproven.

15 May 2025

Customized CRISPR gene editing therapy successfully treats infant with rare disease

In a historic medical breakthrough, a child diagnosed with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy by a team at Children's Hospital of Philadelphia (CHOP) and Penn Medicine.

15 May 2025

Study sheds light on why women have faster heartbeats than men

For decades, doctors and researchers have puzzled over a basic heart rhythm mystery: Why do women tend to have faster heartbeats while men are more likely to develop irregular rhythms like atrial fibrillation (AFib)?

15 May 2025

TMEM219 inhibition shows promise in restoring intestinal health in IBD

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in inflammatory bowel diseases.

15 May 2025

Allen Institute introduces CellScapes to map cellular cooperation

The Allen Institute today announced the launch of CellScapes, a bold new research initiative aimed at revolutionizing how scientists understand and predict the behavior of human cells as they work together to build tissues and organs.

15 May 2025

New stem cell model replicates human amniotic sac development

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization.

15 May 2025

Revolutionary incision-free technique halts growth of brain cavernomas

A new, incision-free technique developed at UVA Health to treat debilitating brain lesions called cerebral cavernous malformations, or cavernomas, has shown great promise in early testing, halting the growth of the lesions almost entirely.

15 May 2025

Innovative technology offers non-invasive way to observe blood clotting

Researchers from the University of Tokyo have found a way to observe clotting activity in blood as it happens - without needing invasive procedures.

15 May 2025

Study deciphers the role of histone deacetylases in lymphoma development

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system.

15 May 2025

SLIRP protein identified as key regulator of immune responses

Even after the COVID-19 pandemic, various new infectious diseases continue to emerge, posing ongoing viral threats that demand robust and sustained immune defenses.

15 May 2025

Air travel disrupts DNA repair in flight crew, raising cancer concerns

Researchers found that flight attendants show reduced DNA repair capacity and immune changes after air travel, which may help explain their higher cancer risk.

14 May 2025

Researchers uncover key role of peri-LC neurons in the brain arousal system

A small cluster of cells deep within our brains, called the locus coeruleus, affects how awake and attentive we are, how we respond to stress, how we cope with anxiety and fear, and how we create memories and learn.

14 May 2025

New technology maps molecules within single cells to uncover disease mechanisms

Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease.

14 May 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

Taurine identified as a key regulator of myeloid cancers

A new scientific study identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia, according to a paper published in the journal Nature.

14 May 2025

Multiple laboratory techniques can provide a wealth of knowledge about brain cancer

Clinicians from the Johns Hopkins Kimmel Cancer Center and four other institutions have demonstrated that doctors can gain a wealth of knowledge about a patient's cancer by using multiple laboratory techniques to study tumor tissue taken from needle biopsies of glioblastoma, a highly aggressive form of brain cancer.

14 May 2025