Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.

21 Mar 2022

UT Dallas researchers explore origins of chronic pain and the potential for better treatments

An investigation into how human nerve cells differ from animal cells has provided researchers from The University of Texas at Dallas' Center for Advanced Pain Studies with important clues in the pursuit of more effective treatments for chronic pain.

19 Mar 2022

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

18 Mar 2022

Hypoxia-inducible factors and SARS-CoV-2 manifestations

Researchers assessed the role of hypoxia-inducible factors in SARS-CoV-2 infection, respiratory symptoms, and epithelial damage.

18 Mar 2022

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia - an uncommon type of cancer of the bone marrow - have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

Research demonstrates within-host seasonal immunity

Researchers investigate the association between seasonal flu changes and gene expression to determine the ‘within-host’ immunity concept.

17 Mar 2022

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.

17 Mar 2022

Transcription factors work together to drive cancer cell proliferation

Scientists have discovered that a well-established cancer cell transcription factor and its newly identified co-factor work together to drive cancer cell proliferation, according to findings published in Science Advances.

16 Mar 2022

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases.

16 Mar 2022

Placenta found to demonstrate anti-oxidant activity against COVID-19 in full-term pregnancy

Researchers assessed the placental anti-oxidant response in the third trimester of pregnancy against SARS-CoV-2 infections.

16 Mar 2022

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers evaluate the feasibility of tonsil epithelial cell-derived organoids as an ex vivo model for studying SARS-CoV-2 infection.

15 Mar 2022

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

The coming of spring harkens spring cleaning; a time to de-clutter your home and discard things that are no longer needed. In the body, a cellular process called autophagy occurs regularly to "de-clutter" our cells.

15 Mar 2022

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

New research has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children.

14 Mar 2022

Scientists map key molecular changes during mouse embryogenesis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

14 Mar 2022

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Researchers analyze the available scientific evidence supporting vitamin D as a neuroprotective agent against the neurological sequelae of COVID-19.

14 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Scientists identify a new protein that turbocharges gene expression

For many years, scientists have sought to understand what happens when our genes are flipped to the "on" position. Now, scientists at the University of California San Diego and Rutgers University have identified a new protein that contributes to this important process.

11 Mar 2022

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Two multi-institutional teams led by Weill Cornell Medicine scientists have been awarded grant support from the Starr Cancer Consortium. Both grants will fund work applying new technologies to develop more detailed knowledge of tumor biology, with one team focusing on Hodgkin lymphoma and the other on the purity of tumor samples on pathology slides.

10 Mar 2022

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Amyloid beta, a protein known to build up in the brains of people with Alzheimer's disease, also helps skin cancer cells thrive when they spread to the brain, a new study finds.

10 Mar 2022

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study.

9 Mar 2022

Gene Expression News and Research

Further Reading

New computational approach creates spatial maps of single-cell data within tissues

UT Dallas researchers explore origins of chronic pain and the potential for better treatments

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

Hypoxia-inducible factors and SARS-CoV-2 manifestations

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

Research demonstrates within-host seasonal immunity

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Transcription factors work together to drive cancer cell proliferation

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

Placenta found to demonstrate anti-oxidant activity against COVID-19 in full-term pregnancy

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Researchers illuminate the link between autophagy and the body's metabolic response to fasting

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

Scientists map key molecular changes during mouse embryogenesis

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Novel genetic relationships with severe SARS-CoV-2

Scientists identify a new protein that turbocharges gene expression

Multi-institutional teams awarded grant support from the Starr Cancer Consortium

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

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