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AGA releases the first comprehensive evidence-based guideline on management of pouchitis

The American Gastroenterological Association (AGA) has released the first comprehensive evidence-based guideline on the management of pouchitis, the most common complication people with ulcerative colitis experience following surgery to remove their colon.

19 Dec 2023

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Study reveals that cinnamon extract significantly inhibits adipocyte differentiation and lipid accumulation, offering potential benefits against obesity by reducing fat production and enhancing lipolysis in both cell models and mice.

18 Dec 2023

Transgenic carrots producing nisin protein show promise as natural food preservatives

Study explores the production of nisin protein in transgenic carrots, demonstrating its potential as a natural preservative effective against bacterial pathogens in food and juices.

18 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Researchers investigated associations between alcohol consumption behaviors, diabetes mellitus, genetic predispositions, and ARLD incidence in 312,59 active drinkers from the United Kingdom Biobank.

18 Dec 2023

Late-night eating linked to higher cardiovascular disease risk, study suggests

Study finds that the timing of meals, particularly late-night eating, is associated with an increased risk of cardiovascular disease, highlighting the importance of meal timing for cardiometabolic health.

17 Dec 2023

Poop-based test predicts postoperative infections in liver transplant patients

In a new study, researchers at the University of Chicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop.

15 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

Atezolizumab plus carboplatin: A winning combination for metastatic triple-negative breast cancer

Immunotherapy in combination with chemotherapy has become an important therapeutic treatment option in some patients with metastatic breast cancer.

14 Dec 2023

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome.

14 Dec 2023

Hidden reservoir revealed: Extracellular vesicles could be potential source of COVID recurrence

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has posed unprecedented challenges worldwide.

14 Dec 2023

Study points to binge drinking and genetics as key factors in liver disease

Those who binge drink and have a certain genetic makeup are six times more likely to develop alcohol-related cirrhosis, according to new research from UCL, the Royal Free Hospital, the University of Oxford and the University of Cambridge.

14 Dec 2023

Study establishes iron accumulation as a driver of pathological senescence and fibrosis

Fibrosis is associated with various chronic and life-threatening conditions, including pulmonary fibrosis, liver cirrhosis, kidney disease, and cardiovascular diseases, among others.

14 Dec 2023

Trends in mortality from leading cancers from 2002 to 2019 for the 314 districts in England

Researchers assessed mortality trends in the leading cancers from 2002 to 2019 across 314 districts in England using high-resolution spatiotemporal analysis.

14 Dec 2023

Paternal alcohol consumption prior to conception can have a negative effect on fetal development

Researchers at Texas A&M University have already shown that paternal drinking habits prior to conception can have a negative effect on fetal development - with semen from men who regularly consume alcohol impacting placenta development, fetal alcohol syndrome (FAS)-associated brain and facial defects, and even IVF outcomes.

13 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

Evaluating the health risks associated with dietary exposure to metals

The problem of foodborne metal contamination has taken on new urgency, thanks in part to a 2021 US Congressional Report detailing high levels of metals found in infant food pulled off grocery shelves.

12 Dec 2023

New optimized vaccine approach targets Hepatitis C virus variability

A method to design vaccines for highly variable viruses like the hepatitis C virus.

12 Dec 2023

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

The current class of anti-obesity drugs is proving remarkably effective at removing excess pounds. However, a phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year.

11 Dec 2023

Liver News and Research

AGA releases the first comprehensive evidence-based guideline on management of pouchitis

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Transgenic carrots producing nisin protein show promise as natural food preservatives

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Late-night eating linked to higher cardiovascular disease risk, study suggests

Poop-based test predicts postoperative infections in liver transplant patients

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Atezolizumab plus carboplatin: A winning combination for metastatic triple-negative breast cancer

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

Hidden reservoir revealed: Extracellular vesicles could be potential source of COVID recurrence

Study points to binge drinking and genetics as key factors in liver disease

Study establishes iron accumulation as a driver of pathological senescence and fibrosis

Trends in mortality from leading cancers from 2002 to 2019 for the 314 districts in England

Paternal alcohol consumption prior to conception can have a negative effect on fetal development

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Evaluating the health risks associated with dietary exposure to metals

New optimized vaccine approach targets Hepatitis C virus variability

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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