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New antibodies protect mice against lethal infections of influenza B virus

Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Louis and Icahn School of Medicine at Mount Sinai.

24 Sep 2020

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

A fourth Phase 3 clinical trial evaluating an investigational vaccine for coronavirus disease 2019 (COVID-19) has begun enrolling adult volunteers.

23 Sep 2020

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Researchers at the University of Cincinnati and UC Health will host a Phase 2 clinical trial (NCT04511650) to examine the effects of a drug that targets blood vessel inflammation and injury in patients with COVID-19.

22 Sep 2020

NIH expands clinical trials to evaluate convalescent plasma as a treatment for COVID-19

Two randomized, placebo-controlled clinical trials funded by the National Institutes of Health (NIH) are expanding enrollment to further evaluate convalescent plasma as a treatment for patients hospitalized with COVID-19.

22 Sep 2020

Targeted therapy improves disease-free survival in patients with early-stage NSCLC

According to updated findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery continues to significantly improve disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) gene mutations.

21 Sep 2020

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival.

21 Sep 2020

COVAM assay may help select convalescent plasma units for treatment of acute COVID-19

A recent study published on the preprint server bioRxiv* seeks to establish the pattern of antibody reactivity in COVID-19 convalescent plasma (CCP), which is widely being used as a therapy for seriously ill COVID-19 patients.

21 Sep 2020

Non-invasive neurotechnology can improve insomnia symptoms and autonomic function

For people with chronic insomnia, a good night's sleep is elusive. But what if insomnia symptoms could be alleviated by simply listening to one's own brainwaves?

17 Sep 2020

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

A study on the effectiveness of multiple treatments, including laboratory-made antibodies, at preventing mild COVID-19 from advancing to severe illness in the outpatient setting is underway by researchers at The University of Texas Health Science Center at Houston (UTHealth).

16 Sep 2020

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

Following a large-scale clinical trial, researchers have found that lanthanum carbonate does not reduce the risk of cardiovascular disease developing in patients with chronic kidney disease.

14 Sep 2020

International trial of blood thinners for COVID-19 treatment begins

These trials, known as ACTIV-4 Antithrombotics, are part of the three planned adaptive trials in this area of clinical research, included in the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative. They are expected to yield new data on the safety and efficacy of these drugs in the treatment of active and convalescent COVID-19 treatment.

13 Sep 2020

Measuring heart rate changes to detect depression risk

For the first time doctors have shown that measuring changes in 24-hour heart rate can reliably indicate whether or not someone is depressed.

11 Sep 2020

Male circumcision campaigns to reduce HIV transmission in Africa are based on systemic racism

World Health Organization-recommended campaigns to circumcise millions of African boys and men to reduce HIV transmission are based more on systemic racism and 'neocolonialism' than sound scientific research, according to a critical appraisal published in Developing World Bioethics.

10 Sep 2020

Intravenous iron therapy does not benefit anemic patients during surgery, study finds

A global study led by researchers at The University of Western Australia has addressed the rising use of intravenous iron therapy in anemic patients during major surgery and found there is little benefit.

10 Sep 2020

Gut microbiota composition and function not related to onset of gestational diabetes

Maternal overweight and obesity increase the risk of gestational diabetes mellitus. Gut microbiota composition has recently been associated with both overweight and a range of metabolic diseases.

9 Sep 2020

Using a pain reliever can increase risk-taking behavior

While acetaminophen is helping you deal with your headache, it may also be making you more willing to take risks, a new study suggests.

8 Sep 2020

Probiotics may help manage obesity in younger population

Probiotics may help children and adolescents with obesity lose weight when taken alongside a calorie-controlled diet, according to a study being presented at e-ECE 2020.

7 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Phase 3 study to test efficacy of new treatment for pediatric acute-onset neuropsychiatric syndrome

Octapharma has launched a phase 3, multi-center superiority study to compare the effectiveness of PANZYGA (immune globulin intravenous, human - ifas) 10% Liquid Preparation versus placebo in patients with pediatric acute-onset neuropsychiatric syndrome (PANS).

3 Sep 2020

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

The University of Chicago Medicine is launching a clinical trial to examine the potential of an antibody against the SARS-CoV-2 spike protein for treating COVID-19, the disease caused by the novel coronavirus.

3 Sep 2020

Placebo News and Research

New antibodies protect mice against lethal infections of influenza B virus

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

NIH expands clinical trials to evaluate convalescent plasma as a treatment for COVID-19

Targeted therapy improves disease-free survival in patients with early-stage NSCLC

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

COVAM assay may help select convalescent plasma units for treatment of acute COVID-19

Non-invasive neurotechnology can improve insomnia symptoms and autonomic function

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

International trial of blood thinners for COVID-19 treatment begins

Measuring heart rate changes to detect depression risk

Male circumcision campaigns to reduce HIV transmission in Africa are based on systemic racism

Intravenous iron therapy does not benefit anemic patients during surgery, study finds

Gut microbiota composition and function not related to onset of gestational diabetes

Using a pain reliever can increase risk-taking behavior

Probiotics may help manage obesity in younger population

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Phase 3 study to test efficacy of new treatment for pediatric acute-onset neuropsychiatric syndrome

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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