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Oral regimens could offer simple solution for severe hyperglycaemia

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes.

10 May 2016

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strategies offer limited protection. In the first of its kind, a report in The American Journal of Pathology describes a potential new intraocular treatment based on manipulating the renin angiotensin system (RAS) that both prevents and reverses some characteristics of diabetic retinopathy in a mouse model.

10 May 2016

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

St. Jude Children's Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a chemotherapy agent for treatment of ependymoma. The research marked the first time the approach has been used to calculate drug doses for a clinical trial in pediatric brain tumor patients.

10 May 2016

Trauma-focused cognitive behavioral therapy effective in overcoming PTSS in children, adolescents

A multicenter randomized controlled trial performed in Germany and published in the current issue of Psychotherapy and Psychosomatics discloses new indications for overcoming trauma in children and adolescents.

10 May 2016

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that mindfulness based cognitive therapy (MBCT) is most helpful when antidepressant drugs are not used.

10 May 2016

Genetic biomarkers may predict response to psychological treatments in anxious children

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that genetic biomarkers may predict response to psychotherapy in anxious children.

10 May 2016

Transcranial direct current stimulation proves effective for binge-eating disorder

Transcranial direct current stimulation, or tDCS, has proved effective for binge-eating disorder for the first time, according to researchers at the University of Alabama at Birmingham.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Neuroimaging studies of interconnected brain networks may provide the "missing links" between behavioral and biological models of cognitive vulnerability to depression, according to a research review in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

10 May 2016

Combination of hormone therapy and radiotherapy halves risk of death from prostate cancer

A longitudinal Nordic study, comparing the results of hormone (antiandrogen) therapy with or without the addition of local radiotherapy, shows that a combination of treatments halves the risk of death from prostate cancer 15 years after diagnosis. This according to a follow-up study recently published in the journal European Urology.

10 May 2016

Study reveals important new findings about rare cancer

A study comprised of 39 international institutions revealed significant new findings about adrenocortical carcinoma (ACC), a rare cancer with an often poor prognosis.

10 May 2016

New article reviews guidelines for folic acid supplementation in pregnancy

Future Science Group today announced the publication of a new article in Future Science OA, reviewing national and international guidelines for folic acid supplementation, and analyzing its potential risks and benefits in terms of maternal and fetal outcomes.

9 May 2016

Younger women more likely to experience one-year adverse cardiovascular events after PCI

Women younger than 55 years of age who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) are more likely to experience one-year adverse cardiovascular events due to risk factors such as diabetes and chronic kidney disease, yet they are less likely to receive potent antiplatelet therapy than men. The PROMETHEUS study found that outcomes for both men and women post-PCI are dependent on their baseline risk factors, not their sex.

9 May 2016

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

A new study finds the use of moderate sedation, in which patients do not need a breathing tube, leads to better clinical outcomes as compared to general anesthesia for patients undergoing transcatheter aortic valve replacement (TAVR).

9 May 2016

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and swallow.

9 May 2016

Unique attributes of zebrafish may help study human blood disorders

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable model organism to study normal hematopoetic development in humans as well as blood disorders and malignancies, as described in a Review article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 May 2016

Study shows testosterone replacement therapy does not increase risk for prostate cancer

Men with low levels of the male sex hormone testosterone need not fear that testosterone replacement therapy will increase their risk of prostate cancer.

9 May 2016

Researchers investigate effects of new steroid treatment on children with ARDS

Acute Respiratory Distress Syndrome (ARDS) affects hundreds of thousands of people each year, many of them children. Those with this life threatening condition have severely injured and wet lungs, and are treated with mechanical ventilation.

9 May 2016

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Patients with atrial fibrillation (AF), a rapid irregular heartbeat caused by pooling blood in the heart which can lead to heart failure and stroke, are often treated with an ablation, a minimally invasive procedure used to remove the tissue which causes the pooled blood.

9 May 2016

Therapy News and Research

Oral regimens could offer simple solution for severe hyperglycaemia

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

Trauma-focused cognitive behavioral therapy effective in overcoming PTSS in children, adolescents

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

Genetic biomarkers may predict response to psychological treatments in anxious children

Transcranial direct current stimulation proves effective for binge-eating disorder

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Combination of hormone therapy and radiotherapy halves risk of death from prostate cancer

Study reveals important new findings about rare cancer

New article reviews guidelines for folic acid supplementation in pregnancy

Younger women more likely to experience one-year adverse cardiovascular events after PCI

Moderate sedation leads to better clinical outcomes than general anesthesia for TAVR patients

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Unique attributes of zebrafish may help study human blood disorders

Study shows testosterone replacement therapy does not increase risk for prostate cancer

Researchers investigate effects of new steroid treatment on children with ARDS

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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