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Review focuses on autologous cell therapy that can be applied to cardiac surgery

The combination of cell and gene therapy is rapidly raising clinical interest, although their combination has been under investigation for several decades. This is mainly due to the availability and feasibility of clinically relevant gene delivery options. This review focuses on cell therapies for heart failure and their use combined with cardiac surgery as well as with gene therapy.

27 Apr 2016

Lilly's ixekizumab (Taltz) granted EC marketing authorisation for treatment of plaque psoriasis

Eli Lilly and Company announced today that the European Commission has granted marketing authorisation for ixekizumab (Taltz) for the treatment of moderate-to-severe plaque psoriasis in adults in the European Union (EU) who are candidates for systemic therapy.

27 Apr 2016

Derivatives of female sex hormones can influence natural melanin production, study suggests

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.

27 Apr 2016

Patients with low education levels more likely to get health information from poorer quality websites

When searching the internet for health information, people with less education and lower literacy levels are more likely to visit poorer quality commercial websites, according to a study by researchers at Loyola Medicine and Loyola University Chicago Stritch School of Medicine.

27 Apr 2016

First small molecule targeted therapy holds promise for Usher syndrome

Usher syndrome (USH) is characterized by hearing loss or deafness at birth and progressive vision loss, and is the most common cause of inherited dual sensory deficit. No treatment is currently available to stop or slow the progression of vision or hearing loss in USH3, one of three clinical classifications for USH that are further divided into subtypes and all associated with different genes.

27 Apr 2016

OSMR gene plays key role in driving growth of glioblastoma tumors

Glioblastoma is the most aggressive type of brain tumor in adults. Unfortunately, there are no effective treatments for the disease. On average, patients succumb just 16 months after diagnosis.

27 Apr 2016

Cholesterol-lowering drugs may not reduce colorectal cancer risk

Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient's risk of colorectal cancer, suggests a new, large case-control study from Penn Medicine researchers published this week in PLOS Medicine.

27 Apr 2016

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

To me the most exciting aspect of pre-clinical imaging is its broad range, from very basic science up to applied science. You deal with a range of disciplines including biology, chemistry, physics, biochemistry, biophysics, cell biology and of course medicine, as the aim is the translation of research to humans.

From Bruker BioSpin Group 27 Apr 2016

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Liver failure often occurs after an extensive hepatectomy, which is the surgical resection of the liver. While liver cell transplantation is a useful therapy for acute liver failure after massive hepatectomy, when cells are transplanted through liver portal veins raises the risk of embolization, such as the formation and movement of a blood clot, often with fatal consequences.

26 Apr 2016

Nutritional supplements can enhance effectiveness of antidepressants

An international evidence review has found that certain nutritional supplements can increase the effectiveness of antidepressants for people with clinical depression.

26 Apr 2016

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

Researchers have identified a rare genetic variation associated with a dramatically increased risk of severe acute pancreatitis in acute lymphoblastic leukemia (ALL) patients treated with the chemotherapy agent asparaginase. St. Jude Children's Research Hospital led the study, which appears today in the Journal of Clinical Oncology.

26 Apr 2016

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

With a cure rate approaching 90 percent, acute lymphoblastic leukemia (ALL) - the most common type of childhood cancer - is often hailed as one of the "success stories" of modern cancer treatment. But up to 20 percent of patients with a high risk of relapse are not cured. That could change with the results from a clinical trial co-led by investigators from NYU Langone Medical Center, which shows giving high doses of a commonly-used chemotherapy drug increases the survival rate for these patients.

26 Apr 2016

New study explores factors that affect Medicare patient’s adherence to psoriasis biologic therapies

About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

26 Apr 2016

TKCI outlines plan to curb corneal blindness worldwide by 2030

The Tej Kohli Cornea Institute in partnership with the world-renowned LV Prasad Eye Institute, has today laid out its plan to control corneal blindness, globally, by 2030.

26 Apr 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

Study shows canine AD shares significant features of human version

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.

26 Apr 2016

Transforming MR images into body composition measurements: an interview with Olof Leinhard

Today's medical science utilizes relatively simple anthropometric measures that describe the body, such as body mass index (BMI) and waist circumference. All of these measures are approximations of the body with the intention to characterize what's inside reflecting underlying phenomena that underpin the risk for different diseases.

26 Apr 2016

Changes in chromatin structure may promote cancer

Cancer development is a complex process involving both genetic and epigenetic changes. Genetic changes in oncogenes and tumor-suppressor genes are generally considered as primary causes, since these genes may directly regulate cellular growth. In addition, it has been found that changes in epigenetic factors, through mutation or altered gene expression, may contribute to cancer development.

26 Apr 2016

Meta-analysis supports combination therapy for PAH patients

A meta-analysis shows that clinical worsening is significantly less likely in patients with pulmonary arterial hypertension if they are given combination treatment, rather than monotherapy.

25 Apr 2016

Brief exercise program can minimize effects of hospitalization, improve functionality of COPD patients

The treatment, designed by scientists at the University of Granada and Virgen de las Nieves Hospital in Granada, allows for cost savings to the health system as it reduces the need for patients to stay in hospital.

25 Apr 2016

Therapy News and Research

Review focuses on autologous cell therapy that can be applied to cardiac surgery

Lilly's ixekizumab (Taltz) granted EC marketing authorisation for treatment of plaque psoriasis

Derivatives of female sex hormones can influence natural melanin production, study suggests

Patients with low education levels more likely to get health information from poorer quality websites

First small molecule targeted therapy holds promise for Usher syndrome

OSMR gene plays key role in driving growth of glioblastoma tumors

Cholesterol-lowering drugs may not reduce colorectal cancer risk

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Nutritional supplements can enhance effectiveness of antidepressants

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

New study explores factors that affect Medicare patient’s adherence to psoriasis biologic therapies

TKCI outlines plan to curb corneal blindness worldwide by 2030

Hydrocortisone drug can also prevent lung damage in premature babies

Study shows canine AD shares significant features of human version

Transforming MR images into body composition measurements: an interview with Olof Leinhard

Changes in chromatin structure may promote cancer

Meta-analysis supports combination therapy for PAH patients

Brief exercise program can minimize effects of hospitalization, improve functionality of COPD patients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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