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Roswell Park Cancer Institute awarded three-years funding for ovarian cancer vaccine

The Ovarian Cancer Research Fund has awarded a $900,000 research grant to Kunle Odunsi, MD, Department of Gynecologic Oncology, and his colleagues at Roswell Park Cancer Institute (RPCI) to collaborate on developing a promising vaccine to unleash the power of the immune system against cancer.

7 Apr 2008

Periodontitis and human papillomavirus combined increase risk for tongue cancer

Persons with periodontitis who also are infected with human papillomavirus (HPV) are at increased risk of developing tongue cancer, new research conducted at the University at Buffalo School of Dental Medicine has shown.

7 Apr 2008

Discovery of new genetic links to psoriasis

In the first comprehensive study of the genetic basis of psoriasis, researchers at Washington University School of Medicine in St. Louis have discovered seven new sites of common DNA variation that increase the risk of the troublesome skin condition.

4 Apr 2008

Researchers learn how signaling molecule orchestrates breast cancer's spread

A study led by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) has uncovered how breast tumors use a particular type of molecule to promote metastasis -- the spread of cancer cells. Metastasis is the cause of approximately 90 percent of all cancer-related deaths.

4 Apr 2008

Human breast tumors' 'microenvironment' primes them for metastasis

The environment within primary breast tumors can "empower" cells that break free and enter the bloodstream to successfully invade other organs, researchers report in the April 4th Cell, a publication of Cell Press.

4 Apr 2008

Light-powered nanomachine kills cancer cells

Researchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light.

2 Apr 2008

Synthetic progestin linked to breast cancer

Millions of post-menopausal women use hormone replacement therapy (HRT) as a method to reduce symptoms associated with menopause.

2 Apr 2008

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

2 Apr 2008

New type of imaging system illuminates tumors to nearly one-trillionth of a meter

Doctors' quest to see what is happening inside a living body has been hampered by the limits on detecting tiny components of internal structures and events.

1 Apr 2008

New tool to identify the molecular signatures of serious diseases

University of Florida chemists are the first to use a new tool to identify the molecular signatures of serious diseases - without any previous knowledge of what these microscopic signatures or "biomarkers" should look like.

1 Apr 2008

Replacing absent microRNAs could make tumors less invasive, more treatable

One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some advanced tumors to more treatable stages, report a University of Chicago-based research team in the April 1, 2008, issue of the journal Genes & Development.

1 Apr 2008

Fasting for two days protects healthy cells against chemotherapy

The chemotherapy worked as intended on cancer, extending the lifespan of mice injected with aggressive human tumors, reported a group led by Valter Longo of the University of Southern California.

1 Apr 2008

Saving cancer patients' skin

Becky Sasaki has the quick laugh and easy smile of a woman who continues to thrive despite her four-year wrestling match with lung cancer.

31 Mar 2008

New method for cancer screening

Ongoing research at Missouri University of Science and Technology has uncovered a new method for the early detection of cancer with the potential to save millions of lives.

31 Mar 2008

New insights into anti-cancer effects of NSAIDs

Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis.

28 Mar 2008

Pectin-rich apple products shown to have anticarcinogenic effects on colon

The apples and apple juice you consume may have positive effects in one of the most unlikely places in the body – in the colon.

28 Mar 2008

New nanoparticles for targeting tumors

As a wide variety of nanoparticles continue to demonstrate their ability to improve the delivery of imaging agents and drugs to tumors, nanoparticle researchers have turned their attention to the challenge of systematically determining how a given nanoparticle’s physical and chemical characteristics affect its ability to target tumors. Such data could provide drug developers with guidelines to help them select the most effective type of nanoparticle for a given therapeutic or imaging application.

28 Mar 2008

Anticancer siRNA therapy advances, thanks to nanoparticles

Small pieces of nucleic acid, known as siRNAs (short interfering RNAs), can turn off the production of specific proteins, a property that makes them one of the more promising new classes of anticancer drugs in development. Indeed, at least two siRNA-based anticancer therapies, both delivered to tumors in nanoparticles, have begun human clinical trials. Now, three new reports highlight the progress that researchers are making in developing broadly applicable, nanoparticle-enabled siRNA anticancer therapeutics.

28 Mar 2008

Study examines association between type of genetic characteristics and cancer

Persons with a certain type of homozygosity (having two identical copies of the same gene, one inherited from each parent), may have a greater predisposition to cancer, according to a study in the March 26 issue of JAMA.

26 Mar 2008

Radiologists use special MRI to identify brain cancer early

A special type of magnetic resonance imaging (MRI) can depict changes in blood volume in the brain that often precede cancerous transformation of brain tumors, according to a new study published in the April issue of the journal Radiology.

26 Mar 2008