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Researchers uncover key role of peri-LC neurons in the brain arousal system

A small cluster of cells deep within our brains, called the locus coeruleus, affects how awake and attentive we are, how we respond to stress, how we cope with anxiety and fear, and how we create memories and learn.

14 May 2025

New technology maps molecules within single cells to uncover disease mechanisms

Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease.

14 May 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

Taurine identified as a key regulator of myeloid cancers

A new scientific study identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia, according to a paper published in the journal Nature.

14 May 2025

Multiple laboratory techniques can provide a wealth of knowledge about brain cancer

Clinicians from the Johns Hopkins Kimmel Cancer Center and four other institutions have demonstrated that doctors can gain a wealth of knowledge about a patient's cancer by using multiple laboratory techniques to study tumor tissue taken from needle biopsies of glioblastoma, a highly aggressive form of brain cancer.

14 May 2025

Urban children have more pro-allergic immune cells than rural peers

Scientists discovered that a previously uncharacterized subset of immune cells may play a critical role in the development of allergic diseases and explain differences between urban and rural populations.

14 May 2025

Study reveals how yellow fever vaccine triggers strong immune response

Researchers show how specific immune cells are activated by the vaccine - an important starting point for the development of new vaccines.

14 May 2025

New approach directly combats the progression of Alzheimer’s and ALS

Scientists at Northwestern University have developed a new approach that directly combats the progression of neurodegenerative diseases like Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

14 May 2025

New glycopeptide antibiotic discovered to combat resistant bacteria

An international team of researchers, led by the University of Vienna and the Helmholtz Institute for Pharmaceutical Research Saarland, has discovered saarvienin A, a new type of glycopeptide antibiotic.

14 May 2025

Solgate streamlines SLC drug discovery with INTEGRA's automated pipetting systems

Solgate - a biotech start-up based in Klosterneuburg, Austria - is accelerating the development of new therapies targeting solute carrier (SLC) transporters using automated liquid handling systems from INTEGRA Biosciences.

14 May 2025

Researchers map brain networks involved in word retrieval

How are we able to recall a word we want to say? This basic ability, called word retrieval, is often compromised in patients with brain damage. Interestingly, many patients who can name words they see, like identifying a pet in the room as a "cat", struggle with retrieving words in everyday discourse.

13 May 2025

HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

Lipid overload in ascites weakens immune response in ovarian cancer

A Ludwig Cancer Research study has identified a key mechanism by which advanced ovarian cancers suppress anti-tumor immune responses and resist immunotherapies.

13 May 2025

DiffInvex identifies key genes driving chemotherapy resistance

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.

13 May 2025

Scientists capture first real time images of heart formation in mouse embryos

Researchers at UCL and the Francis Crick Institute have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo.

13 May 2025

Advanced microscopy reveals how hormonal fluctuations shape the brain

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles.

13 May 2025

Hormone FGF21 reverses fatty liver disease by signaling the brain

A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the brain to improve liver function.

13 May 2025

New light-based 3D printing technique advances tissue engineering

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a technique that could help advance treatments in tissue engineering.

13 May 2025

Breast tissue changes could predict aggressive cancer and poor survival rates

Researchers at the National Institutes of Health (NIH) have identified a series of changes in the architecture and cell composition of connective tissues of the breast, known as stromal tissue, that is associated with an increased risk of developing aggressive breast cancer among women with benign breast disease, and poorer rates of survival among women with invasive breast cancer.

13 May 2025

‘Cell line atlas’ can help better understand biliary tract cancer biology

Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a rare and aggressive group of cancers, carrying one of the worst prognoses in all of oncology.

12 May 2025