Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Computational tools reveal how blood enzyme works at the atomic level

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism.

3 Jan 2022

Researchers identify a biomarker in platelets that tracks the extent of depression

Researchers are one step closer to developing a blood test that provides a simple biochemical hallmark for depression and reveals the efficacy of drug therapy in individual patients.

3 Jan 2022

New study shows how cells eat the things around them

A new study shows how cell membranes curve to create the "mouths" that allow the cells to consume things that surround them.

31 Dec 2021

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19.

28 Dec 2021

Study uncovers new details behind inflammation that promotes cardiovascular disease

High cholesterol and inflammation are key drivers of heart disease, and an inflamed buildup of lipids can cut off the blood supply through a coronary artery to cause a heart attack.

24 Dec 2021

Eating sugar is healthy for some Greenlanders with a genetic variation

A genetic variation among some Greenlanders makes sugar healthy – significantly more than for most people.

22 Dec 2021

Promising new drug target for TB identified

Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell Medicine.

21 Dec 2021

Worsening brain function linked to deep anesthesia during surgery

After surgery under general anaesthesia, older patients often experience a decline in cognitive function that can last for months or even years. This worsening brain function has been linked to deep anesthesia during surgery.

20 Dec 2021

New guidelines for heart-healthy eating

We speak to Dr. Alice Lichtenstein about the American Heart Association’s latest guidelines for a heart-healthy diet, and how they can be applied across different lifestyles.

14 Dec 2021

Diversity in genetic data improves the ability to predict high cholesterol risk

Including data from people of diverse ancestries substantially improves certain genetic risk predictions in all populations, according to a study that examined the genes responsible for regulating blood cholesterol levels.

13 Dec 2021

Novel AI score predicts risk of death in patients with suspected or known coronary artery disease

A novel artificial intelligence score provides a more accurate forecast of the likelihood of patients with suspected or known coronary artery disease dying within 10 years than established scores used by health professionals worldwide.

11 Dec 2021

Prescribing generic heart medications in Medicare Part D could result in substantial savings

Prescribing generic medications for heart and blood vessel diseases more frequently instead of brand-name medications in Medicare's prescription drug program, called Part D, could save more than $600 million each year in the U.S., according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

9 Dec 2021

Environmental exposure to low-levels of toxic metals may increase risk of clogged arteries

Environmental exposure to low-levels of the toxic metals arsenic, cadmium and titanium appears to increase the risk of plaque buildup in arteries in the neck, heart and legs, according to new research published today in the American Heart Association's journal Arteriosclerosis, Thrombosis and Vascular Biology (ATVB).

9 Dec 2021

Diverse genome sequences generate a polygenic risk score to predict heart disease risk

In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.

8 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Novel AI-based system models the progression of chronic diseases as patients age

Using artificial intelligence, a team of University at Buffalo researchers has developed a novel system that models the progression of chronic diseases as patients age.

7 Dec 2021

COVID-19 pandemic linked to higher blood pressure levels among middle-aged U.S. adults

The COVID-19 pandemic is associated with higher blood pressure levels among middle-aged adults across the U.S., according to new research published today in the American Heart Association's flagship journal Circulation.

6 Dec 2021

Statin treatment shown to be cost-effective for lowering cholesterol in young adults

Statin therapy has been shown cost-effective for lowering cholesterol in young adults, according to a study published in the Journal of the American College of Cardiology.

3 Dec 2021

Genetic variant found in Old Order Amish may confer protective effects against cardiovascular disease

Whole-exome sequencing and association analysis in nearly 7,000 Old Order Amish reveals a genetic variant that may confer protective effects against cardiovascular disease (CVD), researchers report.

2 Dec 2021

Study reveals new way for detecting early risk of cardiovascular disease

The risk of developing cardiovascular disease is strongly associated with the "bad" LDL cholesterol. A large study by scientists at Karolinska Institutet now shows that two proteins that transport cholesterol particles in the blood provide early and reliable risk information.

1 Dec 2021