Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

CRIPSR identifies cell-type-specific ACE2 modifiers

Researchers compile a list of candidate genes to identify the surface abundance of functional regulators of ACE2.

9 Mar 2022

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

In a recent study posted to the bioRxiv* preprint server, researchers presented the intragenomic rearrangements of β-coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Whole-genome sequencing for determination of factors associated with critical COVID-19

In a recent study published in the journal Nature as an early release unedited manuscript, researchers conducted whole genomic sequencing (WGS) to ascertain factors contributing to critical coronavirus disease 2019 (COVID-19).

8 Mar 2022

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Leptomeningeal disease is a rare complication of several different types of cancer, including melanoma. It occurs when tumor cells migrate to the cerebrospinal fluid and the tissue that surrounds the brain and spinal column known as the meninges.

8 Mar 2022

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Scientists have shed new light on the role of the placenta in managing the relationships between maternal vitamin D and fetal development, according to a study published today in eLife.

8 Mar 2022

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular mechanisms in mice, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

7 Mar 2022

Study offers insight into molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

7 Mar 2022

Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Potential molecular and clinical biomarkers of COVID-19 severity

Researchers have reviewed the currently published data examining the potential molecular and clinical biomarkers of COVID-19 severity.

4 Mar 2022

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Helsingin yliopisto (University of Helsinki) Insulin is a vital hormone produced by pancreatic beta cells. Type 1 diabetes is caused by the destruction of these cells, which results in patients having to replace the lost insulin with multiple daily injections.

4 Mar 2022

Gene Expression News and Research

Further Reading

CRIPSR identifies cell-type-specific ACE2 modifiers

Intragenomic rearrangements help explain how SARS-CoV-2 variants arise

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Whole-genome sequencing for determination of factors associated with critical COVID-19

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Study offers insight into molecular biology of the brain in bipolar disorder patients

Study explores differentially expressed immune genes for COVID-19 patient stratification

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Potential molecular and clinical biomarkers of COVID-19 severity

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Researchers demonstrate the powerful gene silencing effects of HDO technology

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