Immune System News and Research

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Moffitt scientists develop breakthrough method for scalable synthesis of withanolides

Withanolides, a class of naturally occurring compounds found in plants, have long been a focus of cancer research due to their ability to inhibit cancer cell growth, induce cell death and prevent metastasis.

28 Jun 2024

Enhancing viral therapy for resistant cancers with a metabolite-drug

When a cancer cell doesn't respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying 'troops' in the form of viral agents that are specifically engineered to target and eliminate cancer cells.

28 Jun 2024

Microscopic changes in the liver can be used to predict pancreatic cancer spread

Microscopic changes in the liver can be used to predict if, and where, pancreatic cancer may spread in the body.

28 Jun 2024

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment with immunotherapy and enzymatic tyrosine kinase inhibitors experienced improved health outcomes.

28 Jun 2024

New study links psoriasis severity to skin microbiome dysbiosis

A multi-omics analysis of host-microbe interactions in psoriasis.

28 Jun 2024

Understanding the role of vaccination in mitigating long COVID brain fog

Since the outset of the COVID-19 pandemic, 10 to 30 per cent of the general population has experienced some form of virus-induced cognitive impairment, including trouble concentrating, brain fog or memory loss.

27 Jun 2024

Exposure to urban green and blue spaces may lower odds of having coronary artery calcification

Being near and having more exposure to urban green space and blue (water) space is linked to lower odds of having coronary artery calcification in middle age, which is an early marker of cardiovascular disease.

27 Jun 2024

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

27 Jun 2024

Fighting cancer with nanoparticles

Nanoparticles may be the future of the fight against pancreatic cancer, but also tumours that currently have no cure options. A video news release provides a synthesis of the ULISES project milestones.

27 Jun 2024

A unifying marker streamlines macrophage research across age and sex

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. However, identifying and studying macrophage activation has been challenging due to the complex nature of these cells and their responses.

27 Jun 2024

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

New research led by UCLA Health confirms that both Tai Chi and cognitive behavioral therapy can reduce insomnia in breast cancer survivors but also may provide additional health benefits by reducing inflammation and bolstering anti-viral defenses.

26 Jun 2024

CSF1R marker enables study of Macrophage Activation Mosaicism

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair.

26 Jun 2024

3D drug printers could help personalize medications in the future

Chocolate-flavored pills for children who hate taking medicine.

25 Jun 2024

Designing hybrid antibodies with enhanced mobility and signaling capacity

Antibodies are the body's superheroes, recognizing and eliminating disease-causing substances.

25 Jun 2024

FDA expands orphan drug designation for Roswell Park's brain cancer immunotherapy

The U.S. Food and Drug Administration (FDA) has expanded orphan drug designation for SurVaxM, a brain cancer immunotherapy born in the labs of Roswell Park Comprehensive Cancer Center.

25 Jun 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

Enhancing adoptive T-cell therapy with nanowire innovation

Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells - a type of white blood cell that is part of the body's immune system - are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, or cancer cells.

24 Jun 2024

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

The most common type of malaria in Brazil is caused by the parasite Plasmodium vivax. Although vivax malaria is milder than the variant caused by P. falciparum, the ability of P. vivax to produce dormant forms in the host's liver that can be reactivated months after the end of treatment makes it very hard to control.

24 Jun 2024

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

Researchers developed binary and multiclass machine learning models to distinguish cancer from non-cancerous tissue samples.

24 Jun 2024

JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

Adding an anti-inflammatory drug to anti-PD1 checkpoint inhibitor immunotherapy has shown great promise as a new strategy against advanced lung cancer, based on results from a small clinical trial led by investigators at the Abramson Family Cancer Center at the University of Pennsylvania Perelman School of Medicine.

21 Jun 2024

Immune System News and Research

Moffitt scientists develop breakthrough method for scalable synthesis of withanolides

Enhancing viral therapy for resistant cancers with a metabolite-drug

Microscopic changes in the liver can be used to predict pancreatic cancer spread

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

New study links psoriasis severity to skin microbiome dysbiosis

Understanding the role of vaccination in mitigating long COVID brain fog

Exposure to urban green and blue spaces may lower odds of having coronary artery calcification

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Fighting cancer with nanoparticles

A unifying marker streamlines macrophage research across age and sex

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

CSF1R marker enables study of Macrophage Activation Mosaicism

3D drug printers could help personalize medications in the future

Designing hybrid antibodies with enhanced mobility and signaling capacity

FDA expands orphan drug designation for Roswell Park's brain cancer immunotherapy

Open-source platform enables high-definition spatial transcriptomics

Enhancing adoptive T-cell therapy with nanowire innovation

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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