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Concern over two cases of monkeypox-related neurological complications in the U.S.

A new study published in the CDC's Morbidity and Mortality Weekly Report analyzed two people with encephalomyelitis associated with monkeypox disease in Colorado and DC during the current outbreak.

15 Sep 2022

Combined oral contraceptives associated with elevated risk of venous thromboembolism in obese women

Obese women who use oral contraceptives containing estrogen and progestin have a 24-fold increased risk of venous thromboembolism (VTE) compared with non-obese women not using the drugs, according to a review paper published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).

14 Sep 2022

Neisseria species are linked to worsening bronchiectasis in patients, study shows

A team of international scientists led by the Nanyang Technological University, Singapore (NTU Singapore) has discovered that Neisseria - a genus of bacteria that lives in the human body - is not as harmless as previously thought, and can cause infections in patients with bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD).

14 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

New drug induces similar effects as exercise to aid in the treatment of locomotor frailty

Maintaining a regular workout routine can help you look and feel great – but did you know that exercise also helps maintain your muscles and bones? People who are unable to engage in physical activity experience weakening of the muscles and bones, a condition known as locomotor frailty.

13 Sep 2022

What is the effectiveness of tecovirimat for treatment of monkeypox?

Researchers assessed the effectiveness of tecovirimat in monkeypox treatment in a new study.

13 Sep 2022

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

Researchers identified type 3 vaccine-derived poliovirus (VDPV) in an infant.

13 Sep 2022

$Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer$

Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer.

13 Sep 2022

The impact of the infant gut microbiome on vaccine efficacy

A new study reports the effect of the infant gut microbiome on vaccine efficacy.

13 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

The oral anticoagulant drug apixaban may offer a safer, more effective alternative to standard home heparin injections for patients taking extended prophylaxis (EP) to prevent blood-clot-related complications after surgery, reports a study in The Journal of Urology, an Official Journal of the American Urological Association.

12 Sep 2022

Early life exposure to antibiotics can have long-lasting effects on adult gut health

Preterm and low birth weight babies are routinely given antibiotics to prevent, not just treat, infections, which they have a high risk of developing.

9 Sep 2022

Researchers review role of melatonin in pregnancies complicated by placental insufficiency

A new study explores the role of melatonin in pregnancy.

8 Sep 2022

Triplet therapy slows progression of advanced kidney cancer

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.

8 Sep 2022

AbbVie to present data from its robust migraine portfolio at the Migraine Trust International Symposium 2022

AbbVie today announced that new data from its migraine portfolio will be presented at the Migraine Trust International Symposium (MTIS) 2022, taking place in London from September 8-11.

From AbbVie 8 Sep 2022

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

Researchers investigated the role of antioxidants such as selenium, zinc, α-lipoic acid, and vitamins A, E, D, and C in improving the clinical outcomes of COVID-19.

8 Sep 2022

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

In a recent study posted to the bioRxiv* preprint server, researchers at the U.S National Institutes of Health demonstrated the efficacy of molnupiravir and nirmatrelvir, two oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals in the rhesus macaque model, the closest proxy to humans.

7 Sep 2022

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery.

7 Sep 2022

Recent developments in the use of nanoparticles to deliver drugs to the brain via intranasal administration

Scientists have recently reviewed research articles related to the application of inorganic nanoparticles in delivering drugs to the brain through the intranasal route.

7 Sep 2022

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

Scientists have described the epidemiology, transmission, clinical features, diagnosis, treatment, and preventive strategies of monkeypox infection among humans.

6 Sep 2022

Oral News and Research

Concern over two cases of monkeypox-related neurological complications in the U.S.

Combined oral contraceptives associated with elevated risk of venous thromboembolism in obese women

Neisseria species are linked to worsening bronchiectasis in patients, study shows

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

New drug induces similar effects as exercise to aid in the treatment of locomotor frailty

What is the effectiveness of tecovirimat for treatment of monkeypox?

Study shows vaccine-derived poliovirus in infant with severe immunodeficiency

Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer

The impact of the infant gut microbiome on vaccine efficacy

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

Early life exposure to antibiotics can have long-lasting effects on adult gut health

Researchers review role of melatonin in pregnancies complicated by placental insufficiency

Triplet therapy slows progression of advanced kidney cancer

AbbVie to present data from its robust migraine portfolio at the Migraine Trust International Symposium 2022

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

Recent developments in the use of nanoparticles to deliver drugs to the brain via intranasal administration

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

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