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Physicians failing to talk to stroke patients about end-of-life treatment preferences

US research suggests that physician-patient discussion about limitations on life-sustaining interventions following ischaemic stroke is low, poorly documented and often left too late.

14 Apr 2016

Pluristem granted two key cell therapy patents in Japan

Pluristem Therapeutics Inc. (PSTI), a leading developer of placenta-based cell therapy products, has announced that the Japan Patent Office has granted the Company two key patents addressing...

14 Apr 2016

Innate Immunotherapeutics announces clinical trial fully enrolled and receives strong interest from potential Pharma partners

Innate Immunotherapeutics Limited has closed enrolment into the Company's Phase 2B placebo controlled efficacy trial of MIS416 in patients with secondary progressive multiple sclerosis (SPMS). The study has exceeded the original recruitment target of 90 subjects with the successful enrolment this week of the 93rd patient.

14 Apr 2016

Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

Superbugs – or to give them their correct name, antibiotic resistant bacteria – arise on repeated exposure to antibiotics. In any population of bacteria there will be a few that are antibiotic resistant (approximately 1 in 100 million bacteria). If these bacteria are allowed to grow and multiply, an antibiotic resistant infection results.

13 Apr 2016

TDF, entecavir duo 'highly effective' for difficult-to-treat chronic HBV

The combination of tenofovir disoproxil fumarate and entecavir induces a high rate of viral suppression in patients with chronic hepatitis B virus infection who have failed multiple nucleos(t)ide analogue regimens, phase IIIb results indicate.

13 Apr 2016

Dynamic HBsAg measurements predict HBV inactivity

In patients with hepatitis B e antigen-negative chronic hepatitis B virus infection, repeated measurement of hepatitis B surface antigen during long-term follow-up can help identify those with inactive virus, suggests a chart review.

13 Apr 2016

HLA-C/KIR genotype linked to HBeAg-positive HBV interferon response

The human leucocyte antigen-C and killer immunoglobin-like receptor genotypes are associated with response to interferon-based therapy in patients with chronic hepatitis B virus infection positive for hepatitis B e antigen, say researchers.

13 Apr 2016

Researchers identify protein that helps cancer cells to spread

Aggressive cancer cells spread from a tumour to another part of the body through the blood vessel. To be able get in and out of the blood vessel, the cancer cell needs to penetrate tissue. Researchers from The University of Bergen have discovered a protein that the cancer cell uses like scissors to cut up tissue, so it can spread from a tumour to a new organ.

13 Apr 2016

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, PhD, Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, MD, professor of pediatrics and pharmacy.

13 Apr 2016

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support

The National Alzheimer's Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan's biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.

13 Apr 2016

International scientists discuss new treatments for non small cell lung cancer

More than 30 prominent international scientists gathered to discuss the state-of-the-art, as well as promising future approaches for the treatment of lung cancer at the stunning 17th century Borgo San Luigi, in Monteriggion, in the heart of the Tuscany countryside.

13 Apr 2016

Studies offer alternative conclusions on efficacy of DAAs for HIV and HCV co-infected patients

Two separate studies presented today at The International Liver Congress 2016 in Barcelona, Spain have offered alternative conclusions regarding the efficacy of direct-acting antivirals (DAAs) among patients co-infected with HIV and Hepatitis C virus (HCV).

13 Apr 2016

Toddlers with mobility disabilities less likely to engage in physical activity

Typical toddlers simultaneously spend about three hours a day in physical activity, play and engagement with objects such as toys, while their peers with mobility disabilities are less likely to engage in all of those behaviors at the same time, new research from Oregon State University shows.

13 Apr 2016

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to radiation treatment, and the factors that predict patient outcomes are unclear. Moffitt Cancer Center researchers report that liver metastases have different sensitivities to radiation therapy based on the location of the primary tumor.

13 Apr 2016

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

The advent of targeted drugs for a specific type of breast cancer - HER2 positive - has dramatically improved survival rates for women with the disease. But a study led by researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center reveals low rates of use of a targeted drug among older women with early-stage breast cancer of this type, and even lower rates for older black women.

13 Apr 2016

PTSD patients carry long-term burden even with early clinical interventions

The majority of people with post-traumatic stress disorder (PTSD) recover after early treatment -- but a substantial number still suffer for years after a traumatic event even with early clinical interventions, according to a study publishing online April 12, 2016 in The Journal of Clinical Psychiatry.

13 Apr 2016

Researchers aim to design stable micro-bubbles containing chemotherapeutic drugs

Researchers are now working to design stable micro-bubbles which, combined with ultrasound, can deliver cancer drugs straight to the target tumour.

13 Apr 2016

Dr. Richard Baker and Angela MacMillan launch St. Luke’s OB/GYN at Eaton Pointe

St. Luke’s University Health Network is pleased to announce Richard Baker III, MD, has returned to St. Luke’s University Health Network as the head of St. Luke’s OB/GYN at Eaton Pointe. Angela MacMillan, CRNP, also joins the practice at 800 Eaton Ave., Suite 202, Bethlehem. The two have been in practice together for eight years.

13 Apr 2016

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

RedHill Biopharma Ltd. (NASDAQ; RDHL) (TASE: RDHL) (“RedHill” or the “Company”), a biopharmaceutical company primarily focused on development and commercialization of late clinical-stage, proprietary, orally-administered, small molecule drugs for inflammatory and gastrointestinal diseases, including cancer, today announced that it has initiated a randomized, double-blind, 2-arm parallel group Phase II clinical study in the U.S. evaluating the safety and efficacy of BEKINDA™ 12 mg in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

13 Apr 2016

University’s blindness therapy comes a step closer following landmark licensing deal with US firm

Hundreds of thousands of people worldwide, who have a disease that can lead to blindness, could have their sight restored after The University of Manchester entered into a technology license with Seattle-based company Acucela Inc.

13 Apr 2016

Therapy News and Research

Physicians failing to talk to stroke patients about end-of-life treatment preferences

Pluristem granted two key cell therapy patents in Japan

Innate Immunotherapeutics announces clinical trial fully enrolled and receives strong interest from potential Pharma partners

Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

TDF, entecavir duo 'highly effective' for difficult-to-treat chronic HBV

Dynamic HBsAg measurements predict HBV inactivity

HLA-C/KIR genotype linked to HBeAg-positive HBV interferon response

Researchers identify protein that helps cancer cells to spread

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support

International scientists discuss new treatments for non small cell lung cancer

Studies offer alternative conclusions on efficacy of DAAs for HIV and HCV co-infected patients

Toddlers with mobility disabilities less likely to engage in physical activity

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

PTSD patients carry long-term burden even with early clinical interventions

Researchers aim to design stable micro-bubbles containing chemotherapeutic drugs

Dr. Richard Baker and Angela MacMillan launch St. Luke’s OB/GYN at Eaton Pointe

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

University’s blindness therapy comes a step closer following landmark licensing deal with US firm

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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