Therapy News and Research

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Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Researchers in the group of Prof. Dr. Peter Vandenabeele show that killed tumour cells can serve as a potent vaccine that stimulates the immune system to prevent the outgrowth of cancer cells.

2 Apr 2016

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas (DLBCL). By reducing NFκB signaling, miR-181a controls tumor cell proliferation and survival and could be the target of novel therapies. The study was published in the journal Blood.

2 Apr 2016

Common viruses could produce mild to lethal cardiac injury

A review article has been published in the journal Current Pharmaceutical Design which provides an overview of therecent literature discussing the different clinical forms of heart disease resulting from virus infections including the prognosis, and current therapies.

2 Apr 2016

Mindfulness training can help manage painful cycles of thoughts in veterans with PTSD

Like an endlessly repeating video loop, horrible memories and thoughts can keep playing over and over in the minds of people with post-traumatic stress disorder. They intrude at the quietest moments, and don't seem to have an off switch.

2 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

European researchers aim to spare people with type 1 diabetes from lifelong insulin therapy

More and more children in Europe and the USA are suffering from diabetes. A Group of European Researchers has now joined forces under the leadership of the Gothe University Frankfurt. They are searching for a new method in order to spare people with Diabetes type 1 from lifelong insulin therapy.

2 Apr 2016

Altered metabolism of two essential amino acids helps drive development of glioblastoma

The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Apr 2016

New technologies go far beyond traditional use of contact lenses for vision correction

Imagine contact lenses that can deliver medicines directly to the eye, slow progression of nearsightedness in children, or monitor glucose levels in patients with diabetes.

1 Apr 2016

Researchers apply robust parameter selection, verification techniques to dynamic HIV model

Physical and biological models often have hundreds of inputs, many of which may have a negligible effect on a model's response. Establishing parameters that can be fixed at nominal values without significantly affecting model outputs is often challenging; sometimes these parameters cannot be simply discerned by the outputs.

1 Apr 2016

Experimental urine test identifies 92% of men with elevated PSA levels

An experimental urine test that detects genetic changes associated with prostate cancer identified 92 percent of men with elevated PSA (prostate-specific antigen) levels who had high-grade cancers, according to a study published today in JAMA Oncology online.

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

Right side of the brain reorganizes itself after stroke to help recover speech-motor functions

New research suggests that looking at structures in the right side of the brain may help predict who will better recover from language problems after a stroke, according to a study published in Neurology, a medical journal of the American Academy of Neurology.

31 Mar 2016

Two recently discovered compounds show promise for treating Ewing sarcoma in children

Two recently discovered compounds have shown promise in preclinical studies for treating Ewing sarcoma, a rare cancer that predominantly affects children and adolescents.

31 Mar 2016

Study finds correlation between male sex hormones and oral health

More than 20 species of macaques, the most widely distributed nonhuman primates in the world, socialize in lively troops and make frequent appearances on National Geographic documentaries. But, what can we learn from one of our closest primate relatives about our own oral health?

31 Mar 2016

Blood test to determine risk of heart disease may benefit middle-aged black women

Middle-aged black women have higher levels of a protein in their blood associated with a predictor of heart disease than their white counterparts, even after other factors, such as obesity, are taken into consideration, according to a study conducted by the University of Pittsburgh Graduate School of Public Health and School of Medicine.

31 Mar 2016

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Key opinions leaders in the field of haematopoetic stem cell transplantation (HSCT) will address the role of Cyclophosphamide, an anti-cancer chemotherapy drug, during the 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) that will welcome more than 4,500 delegates in the host city of Valencia, Spain from the 3rd to the 6th of April 2016.

31 Mar 2016

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

Bio Products Laboratory, Limited (BPL) today announced that the European Medicines Agency has granted marketing authorisation for Coagadex.

31 Mar 2016

New tool may help clinicians provide more personalized treatment strategies following coronary stent procedures

Nearly 1 million people in the United States receive coronary artery stents each year. Nearly all stent patients are expected to take dual antiplatelet therapy (DAPT) using the combination of aspirin and a second antiplatelet medication to prevent the formation of blood clots. Exactly how long patients should receive DAPT has been debatable.

30 Mar 2016

Researchers to discuss on innovative cellular therapies during EBMT meeting

Cellular Therapy is an emerging medical science that is today facing a unique developmental phase, well documented by the outstanding and growing numbers of clinical trials.

30 Mar 2016

Study reveals adaptive IGRT for bladder preservation has good oncological outcomes

A prospective study examining a trimodality treatment approach in localized bladder cancer cases using adaptive image-guided, intensity-modulated radiation therapy (IG-IMRT) found that the bladder preservation rate at three years was 83 percent.

30 Mar 2016

Therapy News and Research

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

Common viruses could produce mild to lethal cardiac injury

Mindfulness training can help manage painful cycles of thoughts in veterans with PTSD

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

European researchers aim to spare people with type 1 diabetes from lifelong insulin therapy

Altered metabolism of two essential amino acids helps drive development of glioblastoma

New technologies go far beyond traditional use of contact lenses for vision correction

Researchers apply robust parameter selection, verification techniques to dynamic HIV model

Experimental urine test identifies 92% of men with elevated PSA levels

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

Right side of the brain reorganizes itself after stroke to help recover speech-motor functions

Two recently discovered compounds show promise for treating Ewing sarcoma in children

Study finds correlation between male sex hormones and oral health

Blood test to determine risk of heart disease may benefit middle-aged black women

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

New tool may help clinicians provide more personalized treatment strategies following coronary stent procedures

Researchers to discuss on innovative cellular therapies during EBMT meeting

Study reveals adaptive IGRT for bladder preservation has good oncological outcomes

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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