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Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Intensive therapies to reduce high blood pressure can cut the risk of heart disease in older adults without increasing the risk for falls, according to doctors at Wake Forest Baptist Medical Center.

21 May 2016

Researchers urge specific guidelines for fertility, sexual function counseling in at-risk pediatric patients

The drugs and therapies used to treat medical conditions often come with side effects. Doctors, pharmacists and other health care professionals strive to be sure we are made aware.

20 May 2016

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will provide an update on their extensive oncology pipeline at the annual meeting of the American Society of Clinical Oncology in Chicago, USA, on 3-7 June 2016.

20 May 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Coprophagia linked to neurodegenerative dementia

Coprophagia, eating one's feces, is common in animals but rarely seen in humans. Mayo Clinic researchers reviewed the cases of a dozen adult patients diagnosed with coprophagia over the past 20 years and found that the behavior is associated with a wide range of neuropsychiatric disorders, particularly neurodegenerative dementias.

20 May 2016

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals.

20 May 2016

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.

19 May 2016

New autism classification system defines social communication ability levels among ASD children

Children with autism have a wide range of ability to talk with other people, but it has been difficult to group children by their specific skills.

19 May 2016

Nanoparticle-based gene therapy may hold promise for patients with asthma

A new study has demonstrated a way to deliver a nanoparticle-based gene therapy, in order to repair lungs damaged by chronic allergic asthma and to reduce inflammation that causes asthma attacks.

19 May 2016

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression.

19 May 2016

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Patients with Middle East Respiratory Syndrome (MERS) develop more severe critical illness and have higher mortality than patients with non-MERS severe acute respiratory infection (SARI), according to investigators involved with the largest study of critically ill patients with MERS.

19 May 2016

Penn State researchers link mutation in common virus to fatal brain disease

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.

19 May 2016

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Endometrial cancer is the most common gynecologic cancer in the U.S. Most cases are diagnosed at early stage and have good prognosis. Unfortunately, some patients with early stage and low grade endometrial cancer experience recurrence - and the reasons are not entirely clear.

19 May 2016

Experts find vast mental health treatment gap in China and India

A third of the global burden of disease for mental, neurological and substance use disorders occurs in India and China – more than in all high-income countries combined – yet most people with mental disorders in these countries do not receive needed treatment.

19 May 2016

New Quick Reference Guide set to improve antibiotic prescribing

A Tasmanian initiative to provide a ‘Quick Reference Guide’ to antibiotic prescribing in the community has been embraced by general practitioners (GPs) and is set to improve prescribing, delegates at the National Medicines Symposium in Canberra have heard.

19 May 2016

Clinicians perform UK’s first MRI-guided focused ultrasound treatment for prostate cancer

INSIGHTEC congratulates the medical team at Imperial College Healthcare NHS Trust for performing the first MR-guided focused ultrasound treatment in the United Kingdom for prostate cancer.

19 May 2016

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica.

19 May 2016

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response.

19 May 2016

Therapy News and Research

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Researchers urge specific guidelines for fertility, sexual function counseling in at-risk pediatric patients

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

New frozen faecal bank increases chances of curing a chronic health condition

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Coprophagia linked to neurodegenerative dementia

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

New autism classification system defines social communication ability levels among ASD children

Nanoparticle-based gene therapy may hold promise for patients with asthma

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Penn State researchers link mutation in common virus to fatal brain disease

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Experts find vast mental health treatment gap in China and India

New Quick Reference Guide set to improve antibiotic prescribing

Clinicians perform UK’s first MRI-guided focused ultrasound treatment for prostate cancer

Natural product darwinolide may help combat fatal MRSA infection

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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