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Researchers find major gap in treatment for AF patients at higher risk for stroke

Nearly half of all atrial fibrillation (AF) patients at the highest risk for stroke are not being prescribed blood thinners by their cardiologists, according to a new study by researchers at University of California, San Diego School of Medicine and University of California, San Francisco.

17 Mar 2016

Psoriasis patients experience widespread bone loss

Researchers from the Genes, Development and Disease Group, headed by Erwin Wagner at the Spanish National Cancer Research Centre have discovered that psoriasis patients experience a widespread bone loss as a result of the disease.

17 Mar 2016

Biomarkers may provide novel approaches to monitoring immunosuppressive therapy in organ transplant patients

Recently discovered biomarkers may provide valuable new approaches to monitoring immunosuppressive drug therapy in organ transplant recipients--with the potential for individualized therapy to reduce organ rejection and minimize side effects, according to a special article in the April issue of Therapeutic Drug Monitoring, official journal of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology.

17 Mar 2016

Stimulus-induced discharges in critically ill not linked to in-hospital death

Stimulus-induced rhythmic, periodic or ictal discharges in critically ill patients are not independently associated with in-hospital death, but are often associated with other electrographic abnormalities signalling poor outcomes, electroencephalography findings show.

17 Mar 2016

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

In a study using mice, the Johns Hopkins University School of Medicine infectious disease experts have added to evidence that statin drugs — known primarily for their cholesterol-lowering effects — can significantly reduce the time it takes to clear tuberculosis infection.

17 Mar 2016

Edwards Lifesciences' SAPIEN 3 transcatheter heart valve approved in Japan

Edwards Lifesciences Corporation, the global leader in patient-focused innovations for structural heart disease and critical care monitoring, today announced that the Japanese Ministry of Health, Labor and Welfare approved the Edwards SAPIEN 3 transcatheter heart valve for the treatment of patients suffering from severe, symptomatic aortic stenosis.

16 Mar 2016

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen.

16 Mar 2016

Mindfulness meditation reduces pain without endogenous opioid system

Everyone knows that stubbing your toe hurts. What makes it stop hurting is the body's main pain-blocking process - the natural production of opioids.

16 Mar 2016

MicroRNA can help combat obesity and diabetes

Obesity, which is associated with low-grade inflammation, is an important contributor in the development of diabetes and cardiovascular disease. While the role of several organs including adipose tissue have been implicated in this process, the cell types and factors driving this process have not been clear.

16 Mar 2016

Scientists explore new strategies to prevent onset of type 1 diabetes

Type 1 diabetes affects 30,000 individuals throughout Germany and is the most common metabolic disease in children and adolescents. To halt the ever-increasing incidence, the young investigator group "Immunological Tolerance in Type 1 Diabetes" at the Institute of Diabetes Research directed by Prof. Dr. Anette-Gabriele Ziegler is exploring new strategies to prevent the onset of the disease.

16 Mar 2016

Parent-infant interaction sessions need to focus on at-risk families

To more effectively and efficiently meet the needs of at-risk families, a Georgia State University study suggests the introduction of a technological enhancement to improve acquisition of skills developed during parent-infant sessions.

15 Mar 2016

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

In global clinical trials, patients with advanced metastatic lung cancer who were treated with a targeted immunotherapy drug lived significantly longer and with fewer side effects than those who received standard second-line chemotherapy, according to a new Kaiser Permanente study published today in the journal The Lancet.

15 Mar 2016

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

DelMar Pharmaceuticals, Inc., announced today that the FDA Office of Orphan Products Development (OOPD) has granted orphan drug designation for its lead product candidate, VAL-083, in the treatment of medulloblastoma.

15 Mar 2016

Study could lead to potential new therapeutic target with fewer side effects for hypertension

A team of Vermont investigators has been issued a patent for their discovery of a molecule that rescues damaged blood vessels, yet preserves healthy vessels and could serve as a springboard for a new pharmaceutical therapy with fewer side effects for hypertension - a major risk factor for cardiovascular and kidney disease that effects roughly one in three people in the U.S.

15 Mar 2016

Researchers provide new mechanism for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of visual impairment in people over 50 in developed countries. Although this condition affects up to 20% of people between the ages of 65 and 75, what drives abnormal blood vessels to invade the retina is unknown.

15 Mar 2016

Ibrutinib and idelalisib drugs for chronic lymphatic leukaemia can prolong survival time of high-risk patients

Studies conducted at the Comprehensive Cancer Center at MedUni Vienna and Vienna General Hospital show that the drugs ibrutinib and idelalisib used in the targeted treatment of chronic lymphatic leukaemia can significantly prolong the survival time of high-risk patients.

15 Mar 2016

New blood test may potentially facilitate detection of Alzheimer's disease at early stage

Today, Alzheimer's disease is diagnosed too late. In collaboration with a research team at the university and German Center for Neurogenerative Diseases in Göttingen, Researchers at Ruhr-Universität Bochum have developed a blood test that may potentially facilitate detection of Alzheimer's at an early stage. It is based on an immuno-chemical analysis using an infrared sensor.

15 Mar 2016

Humanoid robot can be used as a tool in therapy for improvement of children with autism

Children with autism have special difficulty in expressing emotions, usually have no social skills and face major problems when communicating. In order to help children with this problem learn to recognize facial expressions in themselves and in others, a group of researchers at the Tec de Monterrey, in Mexico, created a robot using artificial intelligence.

15 Mar 2016

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

The ability to reprogram cells has revolutionized stem cell research with major implications for almost all fields of modern biology. A decade ago Shinya Yamanaka described a procedure that revolutionized stem cell biology. Using a genetic trick that introduces a cocktail of four genes into cultured cells from human biopsies, he was able to generate induced pluripotent stem cells (iPS) from mature skin or blood cells

15 Mar 2016

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Researchers on Mayo Clinic's Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.

15 Mar 2016

Therapy News and Research

Researchers find major gap in treatment for AF patients at higher risk for stroke

Psoriasis patients experience widespread bone loss

Biomarkers may provide novel approaches to monitoring immunosuppressive therapy in organ transplant patients

Stimulus-induced discharges in critically ill not linked to in-hospital death

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

Edwards Lifesciences' SAPIEN 3 transcatheter heart valve approved in Japan

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

Mindfulness meditation reduces pain without endogenous opioid system

MicroRNA can help combat obesity and diabetes

Scientists explore new strategies to prevent onset of type 1 diabetes

Parent-infant interaction sessions need to focus on at-risk families

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

Study could lead to potential new therapeutic target with fewer side effects for hypertension

Researchers provide new mechanism for age-related macular degeneration

Ibrutinib and idelalisib drugs for chronic lymphatic leukaemia can prolong survival time of high-risk patients

New blood test may potentially facilitate detection of Alzheimer's disease at early stage

Humanoid robot can be used as a tool in therapy for improvement of children with autism

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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