Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Saving limbs with drug-eluting stents

Attempts to treat critical limb ischemia in peripheral arterial disease (PAD) patients with below-the-knee angioplasty are still thwarted by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and the continued progression of atherosclerotic disease, leading to tissue death (gangrene) and amputation.

11 Mar 2009

Advances in stem cell research

Scientists at The University of Texas Health Science Center at Houston are on the forefront of stem cell research, developing novel therapies designed to generate heart cells, repair traumatic lung injuries, grow new bone and stanch the spread of cancer cells.

8 Mar 2009

Spun-sugar filaments show potential for regenerating nerves

Researchers at Purdue University have developed a technique using spun-sugar filaments to create a scaffold of tiny synthetic tubes that might serve as conduits to regenerate nerves severed in accidents or blood vessels damaged by disease.

26 Feb 2009

VIA Pharmaceuticals awarded new patent on lead compound VIA-2291

VIA Pharmaceuticals, Inc. has announced the issuance of United States Patent No. 7,495,024 entitled "Phenylalkyl N-Hydroxyureas for Combating Atherosclerotic Plaque", covering the use of VIA's lead compound, VIA-2291, for the treatment of atherosclerosis.

25 Feb 2009

The availability of healthy food choices and your quality of diet is associated with where you live

Researchers examined healthy food availability and diet quality among Baltimore City and Baltimore County, Md., residents and found that availability of healthy foods was associated with quality of diet and 46 percent of lower-income neighborhoods had a low availability of healthy foods.

25 Feb 2009

SYNTAX defines borders between CABG and PCI with TAXUS drug-eluting stents

Coronary artery bypass grafting (CABG) should remain the "standard of care" for patients with complex coronary artery disease, concludes the SYNTAX study, published in the New England Journal of Medicine (online February 18, 2009, Print edition March 5).

23 Feb 2009

Researchers examine role of high cholesterol in prostate cancer

Current research suggests that lowering cholesterol may block the growth of prostate tumors.

23 Feb 2009

High-fat diets inflame fat tissue surrounding blood vessels

A study by researchers at the University of Cincinnati (UC) shows that high-fat diets, even if consumed for a short amount of time, can inflame fat tissue surrounding blood vessels, possibly contributing to cardiovascular disease.

20 Feb 2009

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Using the VAP Cholesterol Test from Atherotech, Inc., University of Maryland researchers have found an association between a rare gene mutation and heart protection.

17 Feb 2009

Study identifies gene variants associated with early-onset myocardial infarction

The largest study ever completed of genetic factors associated with heart attacks has identified nine genetic regions - three not previously described - that appear to increase the risk for early-onset myocardial infarction.

8 Feb 2009

Is rapid transition through menopause linked to earlier onset of heart disease?

An evaluation of 203 women as part of the multifaceted Los Angeles Atherosclerosis Study (LAAS) found that those who transitioned more quickly through menopause were at increased risk for a higher rate of progression of "preclinical atherosclerosis" - narrowing of arteries caused by the thickening of their walls.

29 Jan 2009

Assessing the real risk of heart disease in young people with low short-term risks

Risk stratification has become central to strategies for the prevention of coronary heart disease, with the implication that priority is given to those at highest risk (ie, those with established heart disease).

29 Jan 2009

Inflammation worsens danger due to atherosclerosis

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis.

23 Jan 2009

Stroke telemedicine assessed

Stroke telemedicine is a lifesaving practice that deserves further advancement, Mayo researchers write in the January 2009 issue of Mayo Clinic Proceedings.

19 Jan 2009

Less severe first heart attacks linked to decline in coronary heart disease deaths

The severity of first heart attacks has dropped significantly in the United States - propelling a decline in coronary heart disease deaths, researchers reported in Circulation: Journal of the American Heart Association.

19 Jan 2009

Invatec launches drug-eluting balloon to treat atherosclerosis below the knee

Invatec, a comprehensive innovator of interventional products, today announced the European launch of a new peripheral balloon, the IN.PACT Amphirion paclitaxel-eluting PTA balloon catheter.

15 Jan 2009

Half of people 50 years and younger with low 10-year risk of CVD have high lifetime risk

About half of people 50 years and younger who have a low 10-year or short-term cardiovascular disease (CVD) risk may have a high lifetime risk, researchers report in Circulation: Journal of the American Heart Association.

15 Jan 2009

Oral contraceptives may be safe, but information gaps remain

Introduced in the 1960s, oral contraceptives have been used by about 80 percent of women in the United States at some point in their lives.

15 Jan 2009

Researchers find that healthy, younger adults could be at risk for heart disease

Even younger adults who have few short-term risk factors for heart disease may have a higher risk of developing heart disease over their lifetimes, according to new findings by a UT Southwestern Medical Center researcher.

12 Jan 2009

Australian discovers gene for deadly Kawasaki disease

An Australian researcher has identified genes which could make some children more susceptible to the deadly Kawasaki disease - an inflammatory condition in young children that can damage blood vessels.

12 Jan 2009