Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

30 Nov 2021

Researchers develop novel system for rapid and non-invasive detection of skin cholesterol

Cardiovascular diseases (CVDs) are the leading cause of death globally. Monitoring of lipid in patients with coronary heart disease (CHD) is important for decreasing the incidence of cardiovascular events.

29 Nov 2021

Physical activity may prevent accumulation of metabolic risk factors in menopausal women

A study conducted at the University of Jyväskylä in the Faculty of Sport and Health Sciences shows that menopausal transition is associated with unfavourable changes in metabolic health that may be mitigated with a physically active lifestyle. Especially, physical activity alleviated the increase in systolic blood pressure.

25 Nov 2021

Aspirin use associated with raised risk of heart failure

Aspirin use is associated with a 26% raised risk of heart failure in people with at least one predisposing factor for the condition.

23 Nov 2021

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Study finds gaps and gender differences in management of type 2 diabetes

Type 2 diabetes is a major risk factor of cardiovascular diseases, such as coronary artery disease and heart failure, as well as premature death. To prevent or at least delay complications, regular health care visits and good control of blood glucose, low-density lipoprotein cholesterol (LDL-C) and other risk factors are needed.

22 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Stroke survivors more likely than cancer survivors to continue cigarette smoking

Stroke survivors were more likely to continue cigarette smoking than cancer survivors, raising the risk that they will have more health problems or die from a subsequent stroke or heart disease, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

17 Nov 2021

Death from heart attack or stroke may be the first CVD event in some smokers

Death from a heart attack or stroke may be the first cardiovascular disease (CVD) event in some people who smoke cigarettes and CVD is the leading adverse health effect among smokers, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

17 Nov 2021

Oral PCSK9-inhibitor highly effective at reducing high levels of LDL cholesterol, studies show

Results from two early clinical studies show the first version of an oral PCSK9-inhibitor cholesterol-lowering medicine was well tolerated and highly effective at reducing high levels of LDL cholesterol, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Researchers uncover new genetic link to non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases. It is often associated with obesity and diabetes and is considered a manifestation of metabolic syndrome.

10 Nov 2021

Early or late bedtimes may cause adverse consequences for cardiovascular health

Going to sleep between 10:00 and 11:00 pm is associated with a lower risk of developing heart disease compared to earlier or later bedtimes, according to a study published today in European Heart Journal – Digital Health, a journal of the European Society of Cardiology.

9 Nov 2021

Hispanic adults with peripheral artery disease more likely to be admitted to the hospital through the ER

Hispanics adults hospitalized for treatment of symptoms of peripheral artery disease (PAD) were more likely to access this care by going to the emergency room (ER), and they experienced longer and more expensive hospitalizations than non-Hispanic white patients with PAD, according to preliminary research to be presented at the American Heart Association's Quality of Care and Outcomes (QCOR) Research Scientific Sessions 2021.

8 Nov 2021

Study highlights the importance of reducing air pollution to prevent heart attacks

Reduced air pollution in the U.S. during the COVID-19 shutdown initiated in March 2020 was linked to fewer severe heart attacks, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2021.

8 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

A decades-long friendship and a shared passion for basic science has inspired a $15 million gift to the Division of Biology & Biomedical Sciences (DBBS) at Washington University in St. Louis to fund undergraduate programs and graduate student fellowships in the life sciences.

30 Oct 2021

Study focuses on helping shiftworkers to better manage their eating habits

In Australia, one in every five employees are shift workers. But when you work irregular hours, you eat at irregular hours and this can put you at increased risk of weight gain, type 2 diabetes, and cardiovascular disease.

30 Oct 2021

Women with familial hypercholesterolemia miss out on active treatment because of pregnancy

One in five participants were without treatment for 4 years before, during and after pregnancy. Over 9 000 people live with familial hypercholesterolemia (FH) in Norway, but another 16 000 people may have hereditary high cholesterol without knowing it.

29 Oct 2021

New mechanisms for treating impregnable KRAS mutant cancers with statins

Third-generation cancer immunotherapy, a method of removing cancer using the body's immune system, has shown remarkable clinical benefits in recent years, giving hopes to many researchers and patients.

27 Oct 2021