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Responding to Mpox: Global outbreak, research innovations, and therapeutic strategies

In August 2024, the WHO declared Mpox (formerly known as Monkeypox) a global health emergency due to rising Clade I Mpox cases in Africa and Sweden, highlighting the urgency for coordinated global efforts to monitor and mitigate the spread of the virus.

From Sino Biological Inc. 22 Aug 2024

High dose psilocybin shows similar antidepressant effects to escitalopram

High doses of psilocybin - the active ingredient in magic mushrooms - appears to have a similar effect on depressive symptoms as the selective serotonin reuptake inhibitor (SSRI) drug escitalopram, suggests a systematic review and meta-analysis published in The BMJ today.

21 Aug 2024

Camu-camu extract reduces liver fat in non-alcoholic fatty liver disease

A research team from Université Laval has shown the benefits of camu-camu on non-alcoholic fatty liver disease, which affects over seven million people in Canada.

21 Aug 2024

New analysis highlights CBT's benefits for cancer survivors' mental health

A recent analysis of all relevant published studies reveals clear benefits of Cognitive Behavioral Therapy (CBT) for improving mental health and quality of life in cancer survivors.

21 Aug 2024

Advancing cancer therapy with small molecule immune checkpoint inhibitors

Immunotherapy has revolutionized cancer treatment, with immune checkpoint inhibitors (ICIs) playing a pivotal role.

21 Aug 2024

Review explores the use of medicinal plants against women's diseases in the rural communities of Pakistan

Researchers review the application and utility of traditional medicinal plants in treating gynecological health issues in Pakistan.

21 Aug 2024

Spatial transcriptomics unlocks malaria's liver stage secrets

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite's lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

21 Aug 2024

New fluorescent probe offers non-invasive detection of smell loss

A new fluorescent imaging probe can for the first time objectively and non-invasively measure loss of smell, clinically known as anosmia.

20 Aug 2024

Study highlights benefits of 20-minute mindful breathing for cancer patients

Twenty minutes of mindful breathing, which focuses a person's attention on their breath, can rapidly reduce the intensity and unpleasantness of cancer pain and relieve the associated anxiety, suggest the findings of a small comparative study, published online in the journal BMJ Supportive & Palliative Care.

20 Aug 2024

Self-guided cognitive behavioral therapy app reduces anxiety in young adults

Researchers at Weill Cornell Medicine and NewYork-Presbyterian found that a self-guided cognitive behavioral therapy (CBT) app, called Maya, significantly reduced anxiety in young adults struggling with mental health challenges.

20 Aug 2024

Exploring gene silencing mechanisms for improved RNAi therapeutics

RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer.

20 Aug 2024

Exploring targeted therapies in the complex landscape of multiple myeloma

Multiple myeloma (MM) is a complex hematological malignancy with significant unmet needs. While conventional therapies have significantly improved patient survival, the disease remains incurable.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

First meeting of the International Health Regulations Emergency Committee reports on mpox surge

The Director-General of the World Health Organization (WHO), having concurred with the advice offered by the International Health Regulations (2005) (IHR or Regulations) Emergency Committee regarding the upsurge of mpox 2024 during its first meeting, held on 14 August 2024, has determined, on the same date, that the ongoing upsurge of mpox in the Democratic Republic of the Congo (DRC) and in a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the provisions of the Regulations.

20 Aug 2024

Aceneuramic acid drug receives approval for treatment of patients with GNE myopathy

In order to treat an underserved population of patients with a rare condition whose muscles gradually become weaker until they can no longer walk, a team of researchers across Japan have completed a clinical study to confirm the safety of long-term administration of a therapeutic drug.

20 Aug 2024