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Interaction between dioxin and HLA gene variant activates events associated with rheumatoid arthritis

It has been known for more than three decades that individuals with a particular version of a gene - human leukocyte antigen (HLA) - have an increased risk for rheumatoid arthritis.

19 Apr 2018

Environmental pollutants found to worsen rheumatoid arthritis

Scientists have uncovered a link between the risk of developing rheumatoid arthritis and environmental pollutants, such as cigarette smoke.

19 Apr 2018

New microscopy techniques allow quasi-biochemical studies on living T cells

A joint study by the TU Wien and the Vienna School of Medicine has now led to a surprising result. While most opinion leaders in the field reasoned that T cell receptors must interact with one another for effective immune-signaling, the Viennese study shows: T cell receptors act alone. The study has now been published in the journal Nature Immunology.

19 Apr 2018

Investigational drug may help increase protein levels in babies with spinal muscular atrophy

A preliminary study suggests that an investigational drug may help increase protein levels in babies with spinal muscular atrophy. The open-label study is released today and will be presented at the American Academy of Neurology's 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.

19 Apr 2018

People diagnosed with traumatic brain injury may have increased risk of Parkinson's disease, shows study

People who have been diagnosed with a mild concussion, or mild traumatic brain injury, may have a 56 percent increased risk of developing Parkinson's disease, according to a study published in the April 18, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

19 Apr 2018

Compound derived from immune cells treats psoriasis in mice

A compound derived from immune cells treats psoriasis in mice and holds promise for other autoimmune diseases, according to a new study from Washington University School of Medicine in St. Louis.

18 Apr 2018

Large ALS-causing protein aggregates protect rather than harm neurons

Scientists at the UNC School of Medicine have made a significant advance in the understanding of the complex and fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

17 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening the way for them to become diagnostic tools in the early-detection of cancers, dementia and kidney disease.

13 Apr 2018

Severity of cognitive and language impairment in MS patients

Neurocognitive impairment is frequently encountered in Multiple Sclerosis (MS) patients affecting between 40-65% of these individuals, irrespective of disease duration, severity of physical disability, and at both the earlier and later disease stages, with a tendency to worsen over time.

12 Apr 2018

Aberrant protein prevents self-cleaning of nerve cells in ALS

Scientists have discovered that TDP-43 interferes with lysosomal pathways responsible for its clearance and induces autophagy in ALS.

12 Apr 2018

Study explores relationship between age at menopause and memory

Entering menopause at a later age may be associated with a small benefit to your memory years later, according to a study published in the April 11, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Apr 2018

Houston Methodist-led research focuses on rare, inherited neurodegenerative disorder

A rare, inherited neurodegenerative disorder will soon be the focus of an international clinical research effort led by Houston Methodist and funded by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

10 Apr 2018

ALS and frontotemporal dementia share genetic connections

Nearly half of all patients with amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder, develop cognitive problems that affect memory and thinking.

9 Apr 2018

Parkinson's patients who show depression symptoms may actually have demoralization, study says

People with Parkinson's disease who show signs of depression may actually have a condition called demoralization, according to a study published in the April 4, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. That study found demoralization may be common in Parkinson's disease.

5 Apr 2018

Scientists develop new drug for treating skin lesions in rare intractable disease

Scientists at Osaka University developed a new drug treating skin lesions in tuberous sclerosis complex (TSC), a rare intractable disease, a world first.

5 Apr 2018

Largest-ever study to examine anatomical alterations in the brains of epilepsy patients

An international research consortium used neuroimaging techniques to analyze the brains of more than 3,800 volunteers in different countries. The largest study of its kind ever conducted set out to investigate anatomical similarities and differences in the brains of individuals with different types of epilepsy and to seek markers that could help with prognosis and treatment.

4 Apr 2018

NEOMED professor awarded $2.5 million NIH grant for atherosclerosis research

Northeast Ohio Medical University researcher and professor of integrative medical sciences, Yanqiao Zhang, M.D., has received a five-year, $2.5 million grant from the National Heart, Lung, and Blood Institute, National Institutes of Health, to study the role of hepatic transcription factors in lipid regulation, lipoprotein metabolism, and atherosclerosis, the most common form of cardiovascular disease.

4 Apr 2018

New PET imaging agent could help guide treatments for people with neurological diseases

Researchers have developed a new imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis.

2 Apr 2018

Sclerosis News and Research

Interaction between dioxin and HLA gene variant activates events associated with rheumatoid arthritis

Environmental pollutants found to worsen rheumatoid arthritis

New microscopy techniques allow quasi-biochemical studies on living T cells

Investigational drug may help increase protein levels in babies with spinal muscular atrophy

People diagnosed with traumatic brain injury may have increased risk of Parkinson's disease, shows study

Compound derived from immune cells treats psoriasis in mice

Large ALS-causing protein aggregates protect rather than harm neurons

Novel disease model for ALS and MS can be used to develop new immunotherapies

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Severity of cognitive and language impairment in MS patients

Aberrant protein prevents self-cleaning of nerve cells in ALS

Study explores relationship between age at menopause and memory

Houston Methodist-led research focuses on rare, inherited neurodegenerative disorder

ALS and frontotemporal dementia share genetic connections

Parkinson's patients who show depression symptoms may actually have demoralization, study says

Scientists develop new drug for treating skin lesions in rare intractable disease

Largest-ever study to examine anatomical alterations in the brains of epilepsy patients

NEOMED professor awarded $2.5 million NIH grant for atherosclerosis research

New PET imaging agent could help guide treatments for people with neurological diseases

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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