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PET/CT imaging proves golden for detecting cancer in children

PET/CT imaging exhibits significantly higher sensitivity, specificity and accuracy than conventional imaging when it comes to detecting malignant tumors in children, according to research published in the December issue of the Journal of Nuclear Medicine.

13 Dec 2007

Variant of a tumor suppressor gene associated with aggressive prostate cancer

A variant of a tumor suppressor gene may be associated with an increased risk of aggressive prostate cancer, according to a study published online December 11 in the Journal of the National Cancer Institute.

13 Dec 2007

Crimean Congo hemorrhagic fever virus strips away immune system's defensive measures

When the alert goes out that a virus has invaded the body, cells that have yet to be attacked prepare by "armoring" themselves for combat, attaching specific antiviral molecules to many of their own proteins to help resist the invader.

13 Dec 2007

Epigenomic test that could improve treatment for specific gastric cancers

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center in a recent issue of Journal of Clinical Oncology identifies activation of the enzyme COX-2 in gastric cancer tumors as a prognostic indicator for poor outcome.

12 Dec 2007

Silencing small but mighty cancer inhibitors

Researchers from Johns Hopkins and the University of Pennsylvania have uncovered another reason why one of the most commonly activated proteins in cancer is in fact so dangerous.

10 Dec 2007

Growth factor receptor affects prostate cancer progression

Breeding mice with a gene for a cellular receptor that can be turned on and off-at will-not only enabled researchers at Baylor College of Medicine in Houston to show how prostate cancer progresses, but also provides a model for studying when a drug targeting a gene will have an effect on the cancer.

10 Dec 2007

FDA approves trial for SKCC breast cancer vaccine

The Federal Drug Administration announced Friday approval of a Phase 1 clinical trial designed to study a breast cancer vaccine developed at the Sidney Kimmel Cancer Center.

10 Dec 2007

Study results from Zolinza (vorinostat) in combination with bortezomib for multiple myeloma trial

Results from two investigational Phase I trials of ZOLINZA (vorinostat) in combination with bortezomib provide preliminary anti-tumor activity in patients with relapsed and/or refractory multiple myeloma.

10 Dec 2007

Safe and effective therapy discovered for patients with protein-losing enteropathy

Researchers at the Burnham Institute for Medical Research (Burnham Institute) have developed the first model to study intestinal protein leakage in mice, allowing the team to control and replicate both genetic deficiencies and environmental damages in an in vivo setting.

10 Dec 2007

Adrenalectomy shown to benefit those with mild Cushing syndrome

Researchers at UT Southwestern Medical Center have found that patients with a mild form of Cushing syndrome, a metabolic disorder caused by adrenal tumors, demonstrate substantial clinical improvement after adrenalectomy.

10 Dec 2007

Research findings link weight gain and diabetes to a variety of cancers

During this holiday season with its tempting bounty of edible delights, new research calls attention to the role of the expanding American waistline in health and medicine.

10 Dec 2007

Study shows how mutations in the BRCA1 gene lead to breast cancer

An international team of researchers led by Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center and Sweden's Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer.

10 Dec 2007

New radiotherapy system benefits high-risk patients

A new radiotherapy system that combines high-tech imaging with precision tumor-targeting capability is helping cancer specialists at Stony Brook University Medical Center treat patients.

10 Dec 2007

Breast MRI spots other cancers, may alter treatment plan

In about 20 percent of women with breast cancer who plan to undergo a lumpectomy, breast magnetic resonance imaging reveals important diagnostic information that alters their treatment plan, University of Florida surgeons reported today (Dec. 5).

5 Dec 2007

Discovery of new marker to identify cancer stem cells

Researchers at the University of Michigan Comprehensive Cancer Center have found a marker that can be used to identify stem cells in breast tumors, suggesting a potential simple test that could help determine the best treatment for breast cancer.

4 Dec 2007

UCSF Medical Center advances brain disorder treatment with noninvasive radiosurgery tool

The most advanced noninvasive, radiosurgery tool for treating a variety of brain disorders--including tumors--is now being used by specialists at UCSF Medical Center.

4 Dec 2007

Re-engineered Gleevec reduces heart risks

Using a new bottom-up approach for rational drug design, researchers at Rice University and the University of Texas M. D. Anderson Cancer Center have reengineered the powerful anticancer drug imatinib - best known by its brand name Gleevec - to more specifically target one type of cancer while potentially curbing a rare life-threatening cardiotoxic side effect.

4 Dec 2007