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Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and swallow.

9 May 2016

Unique attributes of zebrafish may help study human blood disorders

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable model organism to study normal hematopoetic development in humans as well as blood disorders and malignancies, as described in a Review article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 May 2016

Study shows testosterone replacement therapy does not increase risk for prostate cancer

Men with low levels of the male sex hormone testosterone need not fear that testosterone replacement therapy will increase their risk of prostate cancer.

9 May 2016

Researchers investigate effects of new steroid treatment on children with ARDS

Acute Respiratory Distress Syndrome (ARDS) affects hundreds of thousands of people each year, many of them children. Those with this life threatening condition have severely injured and wet lungs, and are treated with mechanical ventilation.

9 May 2016

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Patients with atrial fibrillation (AF), a rapid irregular heartbeat caused by pooling blood in the heart which can lead to heart failure and stroke, are often treated with an ablation, a minimally invasive procedure used to remove the tissue which causes the pooled blood.

9 May 2016

New antibody-based therapy may provide better strategy for long-term control of HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades.

9 May 2016

New book highlights importance of hyperacute care for intracerebral hemorrhage

The age-standardized mortality rate for hemorrhagic stroke has decreased worldwide over the past two decades, but incidence, number of deaths, and lost disability-adjusted life-years continue to increase. While hemorrhagic stroke occurs half as frequently globally as ischemic stroke, it causes significantly more deaths and lost DALY.

9 May 2016

Implication of microRNAs in cancer development greater than previously thought

Small, non-coding molecules called microRNAs are known to play an important role in cancer development. Researchers now have shown their significance is greater than previously thought, a finding that could lead to new therapeutic approaches for the most common and deadly form of ovarian cancer.

6 May 2016

Gene therapy could be potential treatment for neuropathic pain in cancer patients

A study providing new information about neuropathic pain afflicting some 90 percent of cancer patients who have had nerve damage caused by tumors, surgery, chemotherapy or radiation indicates gene therapy as a possible treatment.

6 May 2016

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Promising results from the first clinical trials of globin gene transfer to treat beta-thalassemias-inherited forms of anemia-have eliminated the need for blood transfusions in some individuals.

6 May 2016

Study identifies sex differences in statin therapy among coronary artery disease patients

Statins are equally effective at decreasing risk of coronary events in men and women, and yet women are less likely to be prescribed these cholesterol-lowering drugs than men.

6 May 2016

Pulmonary hypertension impacts walking ability in SSc patients

The results of a meta-analysis show the adverse impact pulmonary hypertension has on the walking stamina of patients with systemic sclerosis.

6 May 2016

More evidence for combination therapy benefits in PAH

Another meta-analysis adds to evidence of increased benefits for patients with pulmonary arterial hypertension who are given combination therapy.

6 May 2016

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

A protein called Bim may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma, according to the results of a study by Mayo Clinic researchers led by senior author Haidong Dong, M.D., Ph.D., and published online in the May 5 edition of JCI Insight.

6 May 2016

New technology allows for safer, more precise removal of plaque during atherectomy procedure

Rush Oak Park Hospital is the first hospital in the surrounding area to acquire and use a newly approved technology that allows vascular surgeons to see in real-time the plaque they are removing during an atherectomy, a minimally invasive procedure that helps treat peripheral artery disease (PAD).

6 May 2016

Patient-oriented online health resources can impact clinical outcomes of pancreatic cancer patients

The Internet has become a powerful and important resource for daily life. When patients receive a medical diagnosis, particularly a difficult one like pancreatic cancer, the web can be an essential information tool, helping to enable patients to have meaningful discussions with health care providers. However, new research from Beth Israel Deaconess Medical Center published today in JAMA Surgery suggests that online information about pancreatic cancer is often written at a prohibitively high reading level and lacks accuracy concerning alternative therapies.

6 May 2016

Gene-replacement therapy could be potential treatment option for SMARD1

Spinal muscular atrophy (SMA) is a disease that causes progressive degeneration in the nerve cells that control muscles, thereby causing muscle weakness and eventually death.

6 May 2016

Understanding differences in mental health symptoms in LGBQ community

A study exploring the prevalence of mental health symptoms in the lesbian, gay, bisexual and questioning (LGBQ) community, found that the oft-overlooked questioning and bisexual youth face their own significant challenges, particularly when it comes to depression, anxiety and traumatic distress

6 May 2016

Duke scientists develop human-derived antibody that preferentially attacks cancer cells

A research team from Duke Health has developed an antibody from the body's own immune system that preferentially attacks cancer cells.

6 May 2016

Researchers link global increase in type 1 diabetes to advances in medical care

Researchers from the University of Adelaide say the global increase in cases of type 1 diabetes is directly linked to advances in medical care, with the underlying genetics of the disease more likely to be passed from one generation to the next.

6 May 2016

Therapy News and Research

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Unique attributes of zebrafish may help study human blood disorders

Study shows testosterone replacement therapy does not increase risk for prostate cancer

Researchers investigate effects of new steroid treatment on children with ARDS

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

New antibody-based therapy may provide better strategy for long-term control of HIV

New book highlights importance of hyperacute care for intracerebral hemorrhage

Implication of microRNAs in cancer development greater than previously thought

Gene therapy could be potential treatment for neuropathic pain in cancer patients

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Study identifies sex differences in statin therapy among coronary artery disease patients

Pulmonary hypertension impacts walking ability in SSc patients

More evidence for combination therapy benefits in PAH

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

New technology allows for safer, more precise removal of plaque during atherectomy procedure

Patient-oriented online health resources can impact clinical outcomes of pancreatic cancer patients

Gene-replacement therapy could be potential treatment option for SMARD1

Understanding differences in mental health symptoms in LGBQ community

Duke scientists develop human-derived antibody that preferentially attacks cancer cells

Researchers link global increase in type 1 diabetes to advances in medical care

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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