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Patients benefit from one-on-one counseling session prior to knee or hip replacement surgery

A study at Hospital for Special Surgery finds that patients benefit from a one-on-one education session provided by a physical therapist and access to a custom web portal prior to knee or hip replacement surgery.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Naldemedine significantly improves opioid-induced constipation in patients with chronic non-cancer pain

Shionogi today announced pivotal phase III study (COMPOSE I) results showing that once-daily treatment with naldemedine significantly improved opioid-induced constipation (OIC) compared to placebo in patients with chronic non-cancer pain.

22 Feb 2016

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy designation to PKC412 (midostaurin). PKC412 (midostaurin) is an investigational treatment for adults with newly-diagnosed AML who are FLT3 mutation-positive, as detected by an FDA-approved test, and who are eligible to receive standard induction and consolidation chemotherapy.

19 Feb 2016

Majority of LAHNC patients rely on lifestyle-altering cost-coping strategies to manage treatment

The majority of patients with locally advanced head and neck cancers (LAHNC) rely on cost-coping strategies that alter their lifestyle in order to manage the financial burden of their care, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

For patients treated with definitive radiation therapy (RT) for oropharyngeal cancer caused by human papillomavirus (HPV), the majority of recurrences can be detected by post-treatment imaging at three months and physical exams during the six months following treatment, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Induction chemotherapy fails to improve survival in head and neck cancer patients

Head and neck cancer patients who receive chemotherapy prior to radiation therapy (induction chemotherapy or IC) rather than the standard treatment that combines chemotherapy with radiation (chemoradiation or CRT) show no survival benefit and are less likely to receive a full course of radiation, according to research from the University of Colorado Cancer Center presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Is breast density really linked to breast cancer risk? An interview with Dr Wenlian Zhu

Breast is composed of fatty and dense glandular and fibrous tissues. Breast density is expressed as the fraction of a mammogram occupied by dense tissues.

19 Feb 2016

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

Compared to patients with non-Medicaid insurance, uninsured patients and patients with Medicaid are more likely to present with advanced stages of head and neck cancer and have higher overall and cancer-specific mortality rates, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

Children's Hospital Los Angeles and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA's first NGS panel designed to target biomarkers associated with childhood cancers.

19 Feb 2016

Neuroscientists identify specific enzyme that plays critical role in spinal muscular atrophy

Neuroscientists have discovered a specific enzyme that plays a critical role in spinal muscular atrophy, and that suppressing this enzyme's activity, could markedly reduce the disease's severity and improve patients' lifestyles.

19 Feb 2016

Clot-busting drugs decrease mortality in one of worst forms of hemorrhagic stroke

The use of clot-busting drugs to clear blood from the brain's ventricles may be the first effective strategy to decrease mortality for a type of catastrophic bleeding stroke, according to phase-3 clinical trial results announced Thursday at the International Stroke Conference in Los Angeles.

19 Feb 2016

Chemoradiation improves survival rates among subset of elderly head and neck cancer patients

The addition of chemotherapy (CT) to radiation therapy (RT) improves survival rates among a subset of elderly head and neck cancer patients, specifically those ages 71 to 79 with low comorbidity scores and advanced disease stage, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Select Medical Holdings, Kindred Healthcare agree to exchange five long term acute care hospitals

Select Medical Holdings Corporation today announced that it has signed a definitive agreement to exchange five of its long term acute care hospitals for four long term acute care hospitals currently operated by Kindred Healthcare, Inc. and $800,000 in cash consideration.

18 Feb 2016

Experimental drug candidate may aid traumatic brain injury patients

A new report by University of Kentucky researcher Linda Van Eldik, PhD, describes an experimental drug candidate that may aid patients with traumatic brain injury (TBI).

18 Feb 2016

Motor skill training using exoskeleton device beneficial to people suffering from post-stroke weakness

Motor skill training using a robotic arm exoskeleton may be beneficial to people suffering from post-stroke weakness affecting an entire side of their body, according to research presented this week at the Association of Academic Physiatrists Annual Meeting in Sacramento, Calif.

18 Feb 2016

Carotid stenting noninferior to surgery for asymptomatic patients

The findings of the ACT 1 trial suggest that carotid artery stenting is just as effective as carotid endarterectomy in patients with asymptomatic stenosis.

18 Feb 2016

Tackling insulin resistance may reduce recurrence after stroke

Giving pioglitazone to stroke survivors with insulin resistance but no overt diabetes reduces their risk of having a recurrent vascular event, shows the randomised Insulin Resistance Intervention after Stroke trial.

18 Feb 2016

Combining pain medicine with metal ions could destroy drug-resistant cancer cells

Fighting chemoresistant cancer remains a huge challenge that scientists are tackling from as many angles as they can. One alternative approach involves pairing two groups of compounds -- pain medicine and metal ions -- that have individually shown promise as anti-cancer agents. Scientists report in the ACS journal Inorganic Chemistry that combining the two led to new compounds that could destroy drug-resistant cancer cells and leave most normal cells alone in lab tests.

18 Feb 2016

New drug combination shows promise for patients with non-small cell lung cancer

Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed.

18 Feb 2016

Therapy News and Research

Patients benefit from one-on-one counseling session prior to knee or hip replacement surgery

Researchers identify common molecular alteration in glioblastoma

Naldemedine significantly improves opioid-induced constipation in patients with chronic non-cancer pain

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Majority of LAHNC patients rely on lifestyle-altering cost-coping strategies to manage treatment

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

Induction chemotherapy fails to improve survival in head and neck cancer patients

Is breast density really linked to breast cancer risk? An interview with Dr Wenlian Zhu

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

Neuroscientists identify specific enzyme that plays critical role in spinal muscular atrophy

Clot-busting drugs decrease mortality in one of worst forms of hemorrhagic stroke

Chemoradiation improves survival rates among subset of elderly head and neck cancer patients

Select Medical Holdings, Kindred Healthcare agree to exchange five long term acute care hospitals

Experimental drug candidate may aid traumatic brain injury patients

Motor skill training using exoskeleton device beneficial to people suffering from post-stroke weakness

Carotid stenting noninferior to surgery for asymptomatic patients

Tackling insulin resistance may reduce recurrence after stroke

Combining pain medicine with metal ions could destroy drug-resistant cancer cells

New drug combination shows promise for patients with non-small cell lung cancer

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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