Tumor News and Research

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Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007

Advances in drug screening

With the discovery of suitable molecular targets - cellular molecules along pathways crucial for sustaining the life of cancer cells - comes the perplexing dilemma of where to find the next therapeutics that will bind to and disable those targets.

23 Oct 2007

Extract from broccoli protects skin sun damage

U.S. researchers have discovered that as well as being healthy food, broccoli also helps skin cells fight off damage caused by harmful ultraviolet radiation.

23 Oct 2007

Transparent zebrafish help the study inflammatory breast cancer

What if doctors could peer through a patient's skin and see a cancer tumor growing? They'd be able to study how tumor cells migrate: how they look, how they interact with the blood system to find nourishment to grow and spread through the body.

22 Oct 2007

Heparanase shows potential as cancer drug

Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.

22 Oct 2007

FDA approves approved Ixempra (ixabepilone) for advanced breast cancer

The U.S. Food and Drug Administration has approved Ixempra (ixabepilone), a new anti-cancer treatment, for use in patients with metastatic or locally advanced breast cancer who have not responded to certain other cancer drugs.

22 Oct 2007

Human cytomegalovirus may help doctors treat glioblastoma multiforme

A common human virus may prove useful in attacking the deadliest form of brain tumors, according to a study by researchers at Duke's Preston Robert Tisch Brain Tumor Center.

22 Oct 2007

Emotional well-being not an independent factor affecting the prognosis of head and neck cancers

A patient's positive or negative emotional state has no direct or indirect effect on cancer survival or disease progression, according to a large scale new study.

22 Oct 2007

Extract of broccoli sprouts protects from ultraviolet radiation

A team of Johns Hopkins scientists reports in this week's issue of the Proceedings of the National Academy of Sciences that humans can be protected against the damaging effects of ultraviolet (UV) radiation - the most abundant cancer-causing agent in our environment - by topical application of an extract of broccoli sprouts.

22 Oct 2007

Researcher identify specific cell that causes eye cancer, disproving long-held theory

Investigators at St. Jude Children's Research Hospital have identified the cell that gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development.

19 Oct 2007

New pathway identified by which cancer cells grow and survive

Cancerous tumors are wildly unfavorable environments. Struggling for oxygen and nutrients while being bombarded by the body's defense systems, tumor cells in fact require sophisticated adaptations to survive and grow.

19 Oct 2007

Preventing tuberculosis reactivation

Tuberculosis (TB) is the leading cause of death due to infectious disease in the world today.

19 Oct 2007

Immune cells found to promote formation of new blood vessels - potential for endometriosis treatments

A discovery in mice of immune cells that promote the formation of new blood vessels could lead to new treatments for endometriosis, a painful condition associated with infertility that affects up to 15 percent of women of reproductive age.

19 Oct 2007

Avastin and chemo combo may offer hope for glioblastoma multiforme patients

Brain cancer patients with the poorest prognosis -- those with a type of deadly tumor known as glioblastoma multiforme (GBM) -- may survive longer with a drug that chokes off a tumor's blood supply.

19 Oct 2007

Clinical trial to evaluate glioblastoma multiforme vaccine commences at NYU

A clinical trial evaluating a brain cancer vaccine in patients with newly diagnosed brain cancer has begun at NYU Medical Center.

19 Oct 2007

Intra-arterial combination chemotherapy induces long-term survival for hepatocellular carcinoma

Portal venous tumor thrombus (PVTT) is a crucial factor that can worsen the prognosis of patients with hepatocellular carcinoma (HCC).

18 Oct 2007

Researchers improve accuracy of breast cancer prognoses

One of the many unknowns facing women who are diagnosed with breast cancer is predicting the likelihood that the cancer will spread to other parts of the body – metastasize.

17 Oct 2007

Existing drugs may be useful in treating brain tumors

Scientists have shown how developing brain tumors can turn an encounter with a signaling molecule from a fatal experience for the tumor cells into a cue for their own growth and multiplication.

17 Oct 2007

Is the spleen able to prohibit tumor cell proliferation?

Primary and metastatic tumors of the spleen are described as unusual, excluding involvement by lymphoma.

17 Oct 2007

Nanorods of gold blast tumor cells

Researchers have shown how tiny "nanorods" of gold can be triggered by a laser beam to blast holes in the membranes of tumor cells, setting in motion a complex biochemical mechanism that leads to a tumor cell's self-destruction.

17 Oct 2007