Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Playing elite rugby may affect cognitive function in older age, study shows

Retired male elite rugby union players aged 50+ who suffered three or more rugby-related concussions during their career have no worse average cognitive function than those who had experienced no, one or two concussions, according to a new study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

21 Oct 2021

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

20 Oct 2021

Biomarker predicts severity of SARS-CoV-2 infection in patients

A new study investigates a biomarker to predict the severity of disease in patients infected with SARS-CoV-2.

20 Oct 2021

Study reveals a link between neuroinflammation protein and survival outcomes in glioblastoma patients

Scientists have discovered a new link that could bring the scientific and medical community closer to understanding why glioblastoma, the most common malignant brain tumor, is deadlier in males than females.

18 Oct 2021

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory blood clots amenable to neutralization by a fibrin-targeting monoclonal antibody – opening the door for a completely new strategy to reduce thrombotic inflammation in coronavirus disease 2019 (COVID-19).

17 Oct 2021

Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer

Oncotarget published "Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients" which reported that LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis.

13 Oct 2021

International meeting focuses on screening, early and personalized treatment for atrial fibrillation

Screening, early treatment, and personalized therapy for atrial fibrillation are on the agenda of an international meeting starting today.

12 Oct 2021

Long stays in space appear to cause brain damage

Spending a long time in space appears to cause brain damage. This is shown by a study of five Russian cosmonauts who had stayed on the International Space Station.

12 Oct 2021

Researchers discover molecules in the blood that can indicate impending dementia

Researchers at the DZNE and the University Medical Center Göttingen (UMG) have identified molecules in the blood that can indicate impending dementia. Their findings, which are presented in the scientific journal "EMBO Molecular Medicine", are based on human studies and laboratory experiments. Various university hospitals across Germany were also involved in the investigations.

11 Oct 2021

New scent test for early detection and diagnosis of pancreatic cancer

Oncotarget published "Scent test using Caenorhabditis elegans to screen for early-stage pancreatic cancer" which reported that although early detection and diagnosis are indispensable for improving the prognosis of patients with pancreatic cancer, both have yet to be achieved.

11 Oct 2021

Researchers identify new biomarker for severe COVID-19

During the pandemic, it has become increasingly evident that people with cardiovascular disease and obesity are at a much higher risk of developing very severe, even fatal COVID-19 disease.

8 Oct 2021

Characterization of circulating neutrophils from hospitalized COVID-19 patients

A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with COVID-19.

8 Oct 2021

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

A study published in the journal Clinical Nutrition provides new knowledge on the health effects of a diet rich in nuts.

7 Oct 2021

Deadly subtype of T-cell lymphoma harbors unique mutations

An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in a specific protein signaling pathway, according to a study published in the journal Blood.

7 Oct 2021

New technology shows great promise for early diagnosis of Alzheimer’s disease

A technology developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) shows great promise for diagnosing Alzheimer's disease before symptoms arise, potentially changing the course of research and treatment for this condition, which affects millions of people worldwide and is estimated to be the sixth leading cause of death in the United States.

7 Oct 2021

Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients

In this review, researchers summarized the therapeutic and pathogenic role of IL-7 in patients with COVID-19 and examined the promising role of IL-7 as a vaccine adjuvant.

7 Oct 2021

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Elevated allostatic load was associated with a lower likelihood of completing chemotherapy and a lower overall survival rate in patients with lymph node-positive or high-risk lymph node-negative HER2-negative breast cancer, according to results presented at the 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held online October 6-8, 2021.

6 Oct 2021

Biomarker News and Research

Further Reading

Playing elite rugby may affect cognitive function in older age, study shows

New discovery can pave the way to better diagnostics and therapeutics for asthma and COPD

Biomarker predicts severity of SARS-CoV-2 infection in patients

Study reveals a link between neuroinflammation protein and survival outcomes in glioblastoma patients

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer

International meeting focuses on screening, early and personalized treatment for atrial fibrillation

Long stays in space appear to cause brain damage

Researchers discover molecules in the blood that can indicate impending dementia

New scent test for early detection and diagnosis of pancreatic cancer

Researchers identify new biomarker for severe COVID-19

Characterization of circulating neutrophils from hospitalized COVID-19 patients

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

Deadly subtype of T-cell lymphoma harbors unique mutations

New technology shows great promise for early diagnosis of Alzheimer’s disease

Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

$35.1 million US grant focuses on investigating sleep disorder linked to neurodegeneration

On-demand brain stimulation alleviates severe depression

Using nasopharyngeal microbiota as early biomarker in patients with COVID-19

Event guide: World Clinical Biomarkers & CDx Summit Japan eBook

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