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Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Neonatal ICU mystery: Unraveling the secrets of the prevalent Staphylococcus strain

Researchers delve into the genomes of Staphylococcus capitis isolates prevalent in neonates, revealing transmission patterns and survival tactics of the NRCS-A strain in neonatal ICUs.

8 Oct 2023

Is HPV infection a hidden risk factor for prostate cancer?

In a comprehensive meta-analysis published in Scientific Reports, researchers unveil a significant link between human papillomavirus (HPV) infection and increased risk of prostate cancer, highlighting the importance of considering normal prostate tissues over benign prostatic hyperplasia (BPH) as controls for more accurate conclusions.

8 Oct 2023

Researchers identify two main pathways involved in Alzheimer's disease

Dementia, which includes Alzheimer's disease, currently affects around 1.8 million people in Germany. The exact cause has not yet been clarified, but genetic factors play a significant role in the development of the disease.

6 Oct 2023

Researchers create interpretable neural network to predict complex biological outcomes

A team of New York University computer scientists has created a neural network that can explain how it reaches its predictions.

6 Oct 2023

Study reveals unexpected variation in genetic code of protist

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics.

6 Oct 2023

'Guard mechanism' discovered for protein that attacks microbes in infected cells

Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Genetics linked to placental growth and risk of preeclampsia

New research has shed light on how genetics influences the growth of the placenta, revealing a link to risk of disease in the mother.

5 Oct 2023

CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

5 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

Study finds cluster of common conditions may signal early onset of type 2 diabetes

New research presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct), reveals a marked increase in several common conditions in the years leading up to, and immediately prior to, type 2 diabetes diagnosis, suggesting considerably earlier diagnosis might be possible in some patients.

4 Oct 2023

Study identifies potential new way to protect premature babies from deadly infection

Premature babies in neonatal care units are extremely vulnerable, and susceptible to life-threatening infections.

4 Oct 2023

Genetics may influence a person’s ability to adhere to a vegetarian diet

From Impossible Burger to "Meatless Mondays," going meat-free is certainly in vogue. But a person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new Northwestern Medicine study has found.

4 Oct 2023

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced the Cyto-Mine® platform has been selected by FairJourney Biologics, a world leading end-to-end antibody partner, providing integrated services across antibody discovery, engineering, and production, to expand its cell line development capabilities.

From Fluidic Sciences and Sphere Bio 4 Oct 2023

NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

Genetic testing of one thousand embryos provides insights into human development and IVF

By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

3 Oct 2023

Genomic testing rates soar for Black patients with prostate cancer after introduction of precision medicine navigators

The presence of a clinical navigator to act as a liaison between people with prostate cancer and the health care system greatly increases the likelihood that patients, especially Black patients, will receive advanced testing that can help predict the severity of their disease and guide treatment, a new study suggests.

3 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

A better method to predict polygenic inheritance across multiple ancestries

Researchers report the results obtained from the use of a new PRS calculator called CT-SLEB on a multi-national GWAS database.

2 Oct 2023

Genome News and Research

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Neonatal ICU mystery: Unraveling the secrets of the prevalent Staphylococcus strain

Is HPV infection a hidden risk factor for prostate cancer?

Researchers identify two main pathways involved in Alzheimer's disease

Researchers create interpretable neural network to predict complex biological outcomes

Study reveals unexpected variation in genetic code of protist

'Guard mechanism' discovered for protein that attacks microbes in infected cells

Researchers spearhead a new method to hone in on new cancer drug targets

Genetics linked to placental growth and risk of preeclampsia

CRISPR gene editing study provides insights into how autism gene affects brain development

Progress and challenges in completing the human gene catalogue

Study finds cluster of common conditions may signal early onset of type 2 diabetes

Study identifies potential new way to protect premature babies from deadly infection

Genetics may influence a person’s ability to adhere to a vegetarian diet

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

NIH grant to fund development of new gene therapy platform for brain diseases

Genetic testing of one thousand embryos provides insights into human development and IVF

Genomic testing rates soar for Black patients with prostate cancer after introduction of precision medicine navigators

Microglial states and their impact on Alzheimer's disease

A better method to predict polygenic inheritance across multiple ancestries

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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