Immune System News and Research

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Case study sheds light on CAR-T therapy-related secondary cancers

A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.

13 Jun 2024

Pre-surgery GLP-1 agonists reduce post-operative risks in extreme obesity

A combination of GLP-1 agonists taken before metabolic and bariatric surgery may help patients with extreme obesity lower the risk of post-operative complications, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery 2024 Annual Scientific Meeting.

13 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals - a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses.

12 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy - a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers - is low, despite a Food and Drug Administration warning.

12 Jun 2024

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Roux-en-Y gastric bypass, a type of weight-loss surgery, kept type 2 diabetes in remission for up to 15 years and most of the weight off for up to 20 years in one of the largest long-term studies of patients undergoing the procedure.

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

Macrophages play an unexpected role in the complicated obesity-cancer connection

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Attenuated virus helps eliminate cancer in mice

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice.

11 Jun 2024

Study highlights metabolic surgery's role in diabetes prevention

Patients with pre-diabetes and severe obesity who had metabolic and bariatric surgery were 20-times less likely to develop full-blown type 2 diabetes over the course of 15 years than patients with the condition who did not have surgery, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2024 Annual Scientific Meeting.

11 Jun 2024

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Systematic reviews of medical literature between 2020 to 2024 show bariatric surgery, also known as metabolic or weight-loss surgery, produces the greatest and most sustained weight loss compared to GLP-1 receptor agonists and lifestyle interventions.

11 Jun 2024

Children exposed to tree and weed pollen at increased risk of respiratory health problems

A study published in the European Respiratory Journal has found children who are exposed to tree and weed pollen in urban environments are at increased risk of respiratory health problems, including asthma.

10 Jun 2024

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

When scientists transplanted the gut microbes of aged mice into young "germ-free" mice - raised to have no gut microbes of their own - the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans.

10 Jun 2024

Immune System News and Research

Case study sheds light on CAR-T therapy-related secondary cancers

Pre-surgery GLP-1 agonists reduce post-operative risks in extreme obesity

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Macrophages play an unexpected role in the complicated obesity-cancer connection

Enhancing CAR-T cell therapy with biodegradable scaffolds

Attenuated virus helps eliminate cancer in mice

Study highlights metabolic surgery's role in diabetes prevention

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Children exposed to tree and weed pollen at increased risk of respiratory health problems

Understanding Crohn's disease through 'mini-gut' models

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

Host RNA incorporation linked to chronic hepatitis E infection

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Surprising link between a diverse oral microbiome and better cognitive function in aging

Microneedle patch holds promise for promoting hair regrowth caused by alopecia areata

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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