Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

Livestock may play important role in epidemiology of leptospirosis in sub-Saharan Africa

Leptospirosis, which affects more than one million people worldwide each year, is known to be transmitted to humans from a wide range of animals. Now, researchers reporting in PLOS Neglected Tropical Diseases have discovered that more than 7 percent of the cattle and 1 percent of sheep and goats in local slaughterhouses in northern Tanzania are infected with Leptospira bacteria.

8 Jun 2018

Study finds cattle as possible source of human leptospirosis in Africa

The bacterial infection leptospirosis is increasingly recognized as an important cause of fever in Africa. Now, researchers reporting in PLOS Neglected Tropical Diseases have analyzed the major risk factors for contracting leptospirosis and discovered that rice and cattle farming are associated with acute infection.

8 Jun 2018

Synthetic cannabis use may increase risk of heart attack and stroke

The warning follows their treatment of a 25 year old prison inmate who had no family history of heart disease or traditional cardiovascular risk factors, and who was left with a permanent disability.

8 Jun 2018

New analytical method improves diagnosis and monitoring of cancer

Ten times more sensitive than current techniques, the technique allows, from a blood serum sample, to simultaneously detect different biomarkers related to cancer.

8 Jun 2018

Persistent substance use associated with higher risk of CKD progression and early death

In a study of patients with chronic kidney disease, persistent substance use - especially of hard illicit drugs - was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

8 Jun 2018

Study finds widespread uranium contamination in India's groundwater

A new Duke University-led study has found widespread uranium contamination in groundwater from aquifers in 16 Indian states.

7 Jun 2018

Practicing with fake organs helps surgeon to perform complex cancer surgery

Anthony Camnetar remembers the first time he was told that he had von Hippel-Lindau syndrome, a rare genetic disorder.

7 Jun 2018

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

The number of insurance denials for life-saving hepatitis C drugs among patients with both private and public insurers remains high across the United States, researchers from the Perelman School of Medicine at the University of Pennsylvania reported in a new study published in the journal Open Forum Infectious Diseases.

7 Jun 2018

Study finds factors that help or hinder patient involvement in clinical trials of mitochondrial disease

As clinical trials gear up with the aim of attaining the first FDA-approved treatments for mitochondrial disease, a new study reports for the first time what patients and families say would motivate them for or against participating in such research trials.

7 Jun 2018

Few refreshers about how to stay healthy in summer

Life can be pretty good during the summer – especially for those who heed health advice about sun safety, staying hydrated and getting needed vaccinations before traveling abroad. To optimize the good times, here are few refreshers about how to stay healthy this summer.

7 Jun 2018

Specific impairments within six large-scale brain networks linked to drug addiction behaviors

Specific impairments within six large-scale brain networks during drug cue exposure, decision-making, inhibitory control, and social-emotional processing are associated with drug addiction behaviors, according to a systematic review of more than 100 published neuroimaging studies by experts at the Icahn School of Medicine at Mount Sinai and published Wednesday, June 6 in the journal Neuron.

7 Jun 2018

Genopole opens application process for Shaker and Booster programs to international candidates

Genopole, a French biocluster dedicated to research in the fields of genetics and biotechnology, today announces that it is now accepting applications for the third intake of its support programs titled Shaker, designed for people running innovative projects, and Booster, aimed at companies that are less than two years old.

5 Jun 2018

Experimental drug shows potential to improve bladder function after spinal cord injury

An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function, new research suggests.

5 Jun 2018

FDA approves first Neulasta biosimilar to help decrease infection risk during cancer treatment

The U.S. Food and Drug Administration today approved Fulphila (pegfilgrastim-jmdb) as the first biosimilar to Neulasta (pegfilgrastim) to decrease the chance of infection as suggested by febrile neutropenia (fever, often with other signs of infection, associated with an abnormally low number of infection-fighting white blood cells), in patients with non-myeloid (non-bone marrow) cancer who are receiving myelosuppressive chemotherapy that has a clinically significant incidence of febrile neutropenia.

4 Jun 2018

Researchers report on the sweet side of snake venom toxins

A bite from a lancehead snake can be fatal. Species in the family, found throughout Central and South America, have venom that can disrupt blood clotting and cause hemorrhage, strokes and kidney failure.

4 Jun 2018

Study finds increase in lifestyle-related cancers over the past decade

Lifestyle-related cancers, such as lung, colorectal, and skin cancers, have increased globally over the past decade, according to the most comprehensive analysis of cancer-related health outcomes and patterns ever conducted.

4 Jun 2018

New study examines living kidney donors' concerns on kidney removal

In a new study that examined living kidney donors' concerns about their decision to undergo kidney removal, long-term kidney health, aspects of surgery and recovery, and impacts on life satisfaction were among those that donors felt were most important.

1 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Novel microscope technology offers images of the brain with 4K resolution and 3D visualization

The Department of Neurosurgery at the Icahn School of Medicine at Mount Sinai is one of the first hospitals in the country to use the ZEISS KINEVO 900 microscope, a new surgeon-driven, robotic visualization system that merges the functionality of a surgical microscope with 4K resolution and 3D visualization along with specialized robotic control.

1 Jun 2018

Nephrology News and Research

Further Reading

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Livestock may play important role in epidemiology of leptospirosis in sub-Saharan Africa

Study finds cattle as possible source of human leptospirosis in Africa

Synthetic cannabis use may increase risk of heart attack and stroke

New analytical method improves diagnosis and monitoring of cancer

Persistent substance use associated with higher risk of CKD progression and early death

Study finds widespread uranium contamination in India's groundwater

Practicing with fake organs helps surgeon to perform complex cancer surgery

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

Study finds factors that help or hinder patient involvement in clinical trials of mitochondrial disease

Few refreshers about how to stay healthy in summer

Specific impairments within six large-scale brain networks linked to drug addiction behaviors

Genopole opens application process for Shaker and Booster programs to international candidates

Experimental drug shows potential to improve bladder function after spinal cord injury

FDA approves first Neulasta biosimilar to help decrease infection risk during cancer treatment

Researchers report on the sweet side of snake venom toxins

Study finds increase in lifestyle-related cancers over the past decade

New study examines living kidney donors' concerns on kidney removal

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Novel microscope technology offers images of the brain with 4K resolution and 3D visualization

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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