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Albumin supplementation improves human fertility, fights infection

A new University of California, Irvine-led study reveals albumin (Alb), among the most abundant proteins in the body, activates a proton channel (hHv1), also widespread in the body, giving sperm the ability to penetrate and fertilize an egg, and allowing white blood cells to secrete large amounts of inflammatory mediators to fight infection.

22 Jun 2021

Researchers decode the mechanisms of cell renewal process

The human intestine is made up of more than 40 square meters of tissue, with a multitude of folds on its internal surface that resemble valleys and mountain peaks in order to increase the absorption of nutrients.

22 Jun 2021

RedHill presents positive Phase 2 results for oral opaganib in patients with COVID-19 pneumonia

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced presentation of the positive Phase 2 safety and efficacy data for oral opaganib (Yeliva®, ABC294640) in hospitalized patients with COVID-19 pneumonia at the World Microbe Forum (WMF) 2021 (poster #: 5574).

21 Jun 2021

FLASH radiotherapy could revolutionize future tumor treatments

It could become a breakthrough for future tumor treatments with heavy ions and pave new ways: In the current experiment period FAIR-Phase 0, the GSI Helmholtzzentrum für Schwerionenforschung and the future accelerator center FAIR succeeded in performing a carbon ion FLASH experiment for the first time.

21 Jun 2021

Multivalent antibodies show high potency against SARS-CoV-2 in new study

A new study in the journal Nature Communications describes the process of converting a SARS-CoV-2 antibody into a multivalent form, thus enabling it to bind at various different points with its epitope.

21 Jun 2021

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Recently, researchers discuss their development of cell membrane-based nanoparticles that successfully delivered dexamethasone directly to inflamed lung cells.

21 Jun 2021

New hydrogel-based electrodes snugly conform to the body’s myriad shapes

Arrays of metal electrodes are often used in medical procedures that require monitoring or delivering electrical impulses in the body, such as brain surgery and epilepsy mapping.

21 Jun 2021

Putting the reality in virtual reality with robot-assisted surgery

Cardiac surgeons may be able to better plan operations and improve their surgical field view with the help of a robot.

21 Jun 2021

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias?

21 Jun 2021

A new strategy to combat pathogenic bacterium

Pseudomonas aeruginosa is an opportunistic pathogenic bacterium present in many ecological niches, such as plant roots, stagnant water or even the pipes of our homes. Naturally very versatile, it can cause acute and chronic infections that are potentially fatal for people with weakened immune systems.

21 Jun 2021

RIG-1 agonist shows potent antiviral efficacy against SARS-CoV-2 infection

A team of scientists from the United States has recently revealed the antiviral efficacy of stem-loop RNA 14, a RIG-1 agonist, in controlling severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in mice. The compound reduces the risk of severe coronavirus disease 2019 (COVID-19) by inhibiting viral replication in the lower respiratory tract. The study is currently available on the bioRxiv* preprint server.

18 Jun 2021

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

A new study, released as a preprint on bioRxiv* server, shows that a combination of the biological interferon-α and the small molecule nafamostat are effective against SARS-CoV-2 infection in vitro, as well as in vivo.

18 Jun 2021

Printable biosensor enables simultaneous recording and imaging of tissues, organs during surgery

Surgeons may soon be able to localize critical regions in tissues and organs during a surgical operation thanks to a new, patent-pending Purdue University biosensor that can be printed in 3D using an automated printing system.

18 Jun 2021

Controlling brain state transitions using a molecule responsive to light

A study led by researchers from IBEC and IDIBAPS achieves, for the first time, the control of brain state transitions using a molecule responsive to light, named PAI.

18 Jun 2021

New bio-inks for biosensors could make surgery safer

A research team from Los Alamos National Laboratory and Purdue University have developed bio-inks for biosensors that could help localize critical regions in tissues and organs during surgical operations.

18 Jun 2021

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19.

18 Jun 2021

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

In recent years, significant progress has been made towards the use of high-resolution peripheral computed tomography (HR-pQCT) imaging in research, and new potential for applications in the clinic have emerged, particularly with the advent of second generation devices.

18 Jun 2021

RUDN University doctors find alterations in serum amino acid profile in children with ADHD

RUDN University doctors found alterations in serum amino acid profile in children with attention deficit hyperactivity disorder (ADHD).

17 Jun 2021

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

17 Jun 2021

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

The normal function of uromodulin, a protein that is made in the kidney and secreted into the urine, remains largely unknown. However, higher levels of uromodulin in the urine are related to lower rates of urinary tract infections and kidney stones, while higher levels of this protein in kidney cells are associated with higher rates of hypertension and chronic kidney disease.

17 Jun 2021

in vivo News and Research

Albumin supplementation improves human fertility, fights infection

Researchers decode the mechanisms of cell renewal process

RedHill presents positive Phase 2 results for oral opaganib in patients with COVID-19 pneumonia

FLASH radiotherapy could revolutionize future tumor treatments

Multivalent antibodies show high potency against SARS-CoV-2 in new study

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

New hydrogel-based electrodes snugly conform to the body’s myriad shapes

Putting the reality in virtual reality with robot-assisted surgery

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

A new strategy to combat pathogenic bacterium

RIG-1 agonist shows potent antiviral efficacy against SARS-CoV-2 infection

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

Printable biosensor enables simultaneous recording and imaging of tissues, organs during surgery

Controlling brain state transitions using a molecule responsive to light

New bio-inks for biosensors could make surgery safer

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

New guidance provides valuable direction in the clinical use of HR-pQCT imaging

RUDN University doctors find alterations in serum amino acid profile in children with ADHD

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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