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Anti-TNF therapy linked to ‘modest’ extra SCC risk

A Swedish population-based study shows that treatment with tumour necrosis factor inhibitors significantly increases the risk of developing squamous cell carcinoma, but not basal cell carcinoma, in patients with rheumatoid arthritis.

12 Feb 2016

Ultrasound-activated microbubbles help preserve healthy heart tissue

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering used ultrasound-activated microbubbles to improve preservation of heart muscle and function in a pig heart attack model.

12 Feb 2016

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters.

12 Feb 2016

CNIO researchers reveal how combination of dasatinib and demcizumab reduces lung adenocarcinomas

Lung cancer is one of the most prevalent types of cancer, with more than 20,000 new cases diagnosed each year in Spain. Lung adenocarcinomas carrying oncogenic KRAS, the engine driving these tumours in 30% of cases, constitute the most aggressive sub-type because, unlike other types of lung cancer, there are no targeted therapies beyond the standard cisplatin-based treatment.

12 Feb 2016

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter and year ended December 31, 2015.

12 Feb 2016

ASTRO encourages policymakers to increase financial support for cancer research in FY 2017 Budget

The American Society for Radiation Oncology commends the proposed investment in cancer-related research announced in the Fiscal Year 2017 Budget released yesterday by the White House.

12 Feb 2016

ASTRO's new research journal 'Advances in Radiation Oncology' closes first issue

Advances in Radiation Oncology, ASTRO's new original research journal, has closed its first issue with research including a phase II clinical trial in prostate cancer, a prospective trial in quality of life for breast cancer patients receiving radiotherapy and several clinical and medical physics reports on the use of stereotactic body radiotherapy.

12 Feb 2016

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Activity-dependent neuroprotective protein (ADNP), essential for brain formation, is frequently mutated in children on the autism spectrum. In older men and women, ADNP expression in the blood is correlated with cognition and further altered in Alzheimer's disease.

11 Feb 2016

West Cancer Center introduces promising new treatment method for brain cancer patients

Brain Cancer patients in the Mid-South now have a promising new treatment method at West Cancer Center. Optune™, a portable device using low intensity electric fields to inhibit cancer cell replication causing death of cancer cells, is the first FDA-approved therapy in more than a decade to show a significant extension in overall survival rates for newly diagnosed adult Glioblastoma Multiforme (GBM) patients.

11 Feb 2016

Study looks at post-treatment resources for prostate cancer patients transitioning to survivorship

The System Partner of Rutgers Cancer Institute of New Jersey, Meridian Health is joining forces with Rutgers Cancer Institute in offering access to a research study aimed at prostate cancer patients who are transitioning to survivorship.

11 Feb 2016

Review of EAS cases among patients with psychiatric conditions in the Netherlands

A review of euthanasia or assisted suicide (EAS) cases among patients with psychiatric disorders in the Netherlands found that most had chronic, severe conditions, with histories of attempted suicides and hospitalizations, and were described as socially isolated or lonely, according to an article published online by JAMA Psychiatry.

11 Feb 2016

Vanderbilt physicians examine risk factors for cardiovascular disease in prostate cancer survivors

The 3 million prostate cancer survivors in the United States are likely to die from something other than cancer, thanks to early detection, effective treatment and the disease's slow progression.

11 Feb 2016

Scientists propose use of mathematical models to find better treatment for bladder cancer

MIPT scientists together with their colleagues from St. Petersburg and Israel have analyzed more than 500 previously published scientific articles and proposed their own approach to the choice of methods used for the treatment of one of the most common cancers.

11 Feb 2016

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Researchers from Kumamoto University, Japan have identified a protein that limits the severity of Alport syndrome, a type of genetic kidney disease. The finding can provide clues that point toward new therapeutic approaches for Alport syndrome.

11 Feb 2016

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Pediatric acute lymphoblastic leukemia (ALL) patients treated with chemotherapy alone remain at risk for attention and learning problems that persist after treatment ends, according to St. Jude Children's Research Hospital investigators.

10 Feb 2016

LMU researchers identify new drug target for atherosclerosis

The enzyme Dicer processes RNA transcripts, cutting them into short segments that regulate the synthesis of specific proteins. An Ludwig-Maximilians-Universitaet in Munich team has shown that Dicer promotes the development of atherosclerosis, thus identifying a new drug target.

10 Feb 2016

TxCell to update on recent achievements in cellular therapy market at leading forthcoming investor conferences

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T-cells to treat severe chronic inflammatory and autoimmune diseases, announces today that Stephane Boissel, CEO, TxCell and other senior management will either attend, present to, and meet investors at a number of leading forthcoming investor conferences.

10 Feb 2016

Internet-based social interventions important for healthy ageing

Meaningful and Internet-based activities promote experiences of participation in society and are important for healthy ageing. In a new dissertation at Umeå University in Sweden, occupational therapists are shown to promote participation, reduce experiences of loneliness and strengthen seniors' social network using an Internet-based intervention programme.

10 Feb 2016

Oral therapeutic drug shows promise against recurrent C. difficile infection

Results from a Phase 1b/2 trial suggest that an investigational microbiome-based, oral therapeutic drug is effective for the treatment of recurrent C. difficile infection. In a paper published online in the Journal of Infectious Diseases, a multi-institutional research team reports that treatment with the preparation, containing the spores of approximately 50 species of beneficial bacteria, successfully prevented recurrence of C. difficile infection (CDI) in patients with a history of multiple recurrent disease.

10 Feb 2016

Hormone therapy may improve psychological functioning in transgender individuals

Transgender individuals may experience significant improvement in psychological functioning after as little as 3-6 months of hormone therapy, with improved quality of life reported within 12 months of initiating therapy by both female-to-male and male-to-female transgender individuals, according to an article published in Transgender Health, a new peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers.

10 Feb 2016

Therapy News and Research

Anti-TNF therapy linked to ‘modest’ extra SCC risk

Ultrasound-activated microbubbles help preserve healthy heart tissue

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

CNIO researchers reveal how combination of dasatinib and demcizumab reduces lung adenocarcinomas

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

ASTRO encourages policymakers to increase financial support for cancer research in FY 2017 Budget

ASTRO's new research journal 'Advances in Radiation Oncology' closes first issue

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

West Cancer Center introduces promising new treatment method for brain cancer patients

Study looks at post-treatment resources for prostate cancer patients transitioning to survivorship

Review of EAS cases among patients with psychiatric conditions in the Netherlands

Vanderbilt physicians examine risk factors for cardiovascular disease in prostate cancer survivors

Scientists propose use of mathematical models to find better treatment for bladder cancer

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

LMU researchers identify new drug target for atherosclerosis

TxCell to update on recent achievements in cellular therapy market at leading forthcoming investor conferences

Internet-based social interventions important for healthy ageing

Oral therapeutic drug shows promise against recurrent C. difficile infection

Hormone therapy may improve psychological functioning in transgender individuals

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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