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Bone loss linked with ALL therapy occurs during first month of treatment

Investigators at Children's Hospital Los Angeles have found that significant bone loss - a side effect of chemotherapy for acute lymphoblastic leukemia (ALL) - occurs during the first month of treatment, far earlier than previously assumed. Results of the study will be available online February 4, in advance of publication in the journal Bone.

5 Feb 2016

Duke scientists reveal how gut inflammation increases colon cancer risk

Chronic inflammation in the gut increases the risk of colon cancer by as much as 500 percent, and now Duke University researchers think they know why.

5 Feb 2016

Early use of influenza drug in pregnant women with flu may reduce length of stay in hospital

Pregnant women are at higher risk for serious illness and complications, including death, from influenza. For expectant mothers hospitalized with flu, early treatment with the influenza antiviral drug oseltamivir may shorten their time in the hospital, especially in severe cases, suggests a new study published in The Journal of Infectious Diseases and available online.

5 Feb 2016

African-American patients with connective tissue diseases at risk for cardiovascular disease

A study based on medical records from more than a quarter million adult patients found that African-American patients with connective tissue diseases such as lupus or rheumatoid arthritis were twice as likely as white patients to suffer from narrowed or atherosclerotic blood vessels, which increase the risk of a heart attack, stroke or death.

5 Feb 2016

Oncofertility complications reviewed for US patients

Three articles published in JAMA Oncology highlight the legal and clinical care issues surrounding fertility preservation in US patients with cancer.

4 Feb 2016

Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Björn Wängler

Interview conducted with Professor Björn Wängler, Professor for Molecular Imaging and Radiochemistry from Heidelberg University.

From Bruker BioSpin Group 4 Feb 2016

Cell Therapy Catapult becomes Cell and Gene Therapy Catapult

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the official change of its name to the Cell and Gene Therapy Catapult.

4 Feb 2016

NICE recommends Xofigo (radium-223 dichloride) for prostate cancer patients after treatment with docetaxel

The National Institute for Health and Care Excellence has issued its final guidance recommending Xofigo for use on the NHS in England and Wales as an option for treating adult men, with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastases, who have received previous docetaxel therapy.

4 Feb 2016

Texting could promote medication adherence among chronically ill patients

Text messages can double the odds of medication adherence in patients with chronic disease. That is the central finding of a new study published today in JAMA Internal Medicine.

4 Feb 2016

New research identifies key enzyme linked to age-related increases in cancer and inflammation

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

4 Feb 2016

Authors examine link between irrational thoughts and psychological distress

In the current issue of Psychotherapy and Psychosomatics the link between irrational thoughts and distress is critically examined. Since the cognitive revolution of the early 1950s, thoughts have been discussed as central components in the understanding and treatment of mental illnesses.

3 Feb 2016

Researchers identify new targets that may help prevent and cure colon cancer

When the audio on your television set or smart phone is too loud, you simply turn down the volume. What if we could do the same for the signaling in our bodies that essentially causes normal cells to turn cancerous? New discoveries by researchers at the Stephenson Cancer Center at the University of Oklahoma may point to new ways to do just that.

3 Feb 2016

Combined MRI and ultramicroscopy toolkit could help study vessel growth in glioma models in more detail

Stopping the growth of blood vessels in tumours is a key target for glioblastoma therapies, and imaging methods are essential for initial diagnosis and monitoring the effects of treatments. While mapping vessels in tumours has proven a challenge, researchers have now developed a combined magnetic resonance imaging (MRI) and ultramicroscopy 'toolkit' to study vessel growth in glioma models in more detail than previously possible.

3 Feb 2016

New study finds steep decline in basic science publications

A new study has found a steep decline in the number of scholarly papers about basic science published in leading medical journals in the last 20 years.

3 Feb 2016

New analysis method may help categorise stroke patients with language problem

Brain researcher Karsten Specht has found a new method of analysis to distinguish between stroke patients with language problem. The result may be individualised treatment for each patient.

3 Feb 2016

New gene cut-and-paste methods help correct disease-causing mutation in animal model

For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.

3 Feb 2016

Edwards Lifesciences' global sales grow 8.6% to $671.1 million in fourth quarter 2015

Edwards Lifesciences Corporation, the global leader in patient-focused innovations for structural heart disease and critical care monitoring, today reported financial results for the quarter ended December 31, 2015.

3 Feb 2016

ST Asia signs licensing deal with PharmaMar to distribute new multiple myeloma drug in South East Asia

International biopharmaceutical company Specialised Therapeutics Asia will supply and distribute a novel oncology drug candidate throughout South East Asia, following an exclusive licensing deal with European pharmaceutical company PharmaMar.

3 Feb 2016

Genetic profiling ‘feasible’ for paediatric cancer patients

Research published in JAMA Oncology demonstrates that tumour and germline molecular profiling is feasible in paediatric cancer patients and can have actionable findings.

2 Feb 2016

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

The mechanisms underlying the stability and plasticity of neural circuits in the hippocampus, the part of the brain responsible for spatial memory and the memory of everyday facts and events, has been a major focus of study in the field of neuroscience. Understanding precisely how a "healthy" brain stores and processes information is crucial to preventing and reversing the memory failures associated with Alzheimer's disease (AD), the most common form of late-life dementia.

2 Feb 2016

Therapy News and Research

Bone loss linked with ALL therapy occurs during first month of treatment

Duke scientists reveal how gut inflammation increases colon cancer risk

Early use of influenza drug in pregnant women with flu may reduce length of stay in hospital

African-American patients with connective tissue diseases at risk for cardiovascular disease

Oncofertility complications reviewed for US patients

Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Björn Wängler

Cell Therapy Catapult becomes Cell and Gene Therapy Catapult

NICE recommends Xofigo (radium-223 dichloride) for prostate cancer patients after treatment with docetaxel

Texting could promote medication adherence among chronically ill patients

New research identifies key enzyme linked to age-related increases in cancer and inflammation

Authors examine link between irrational thoughts and psychological distress

Researchers identify new targets that may help prevent and cure colon cancer

Combined MRI and ultramicroscopy toolkit could help study vessel growth in glioma models in more detail

New study finds steep decline in basic science publications

New analysis method may help categorise stroke patients with language problem

New gene cut-and-paste methods help correct disease-causing mutation in animal model

Edwards Lifesciences' global sales grow 8.6% to $671.1 million in fourth quarter 2015

ST Asia signs licensing deal with PharmaMar to distribute new multiple myeloma drug in South East Asia

Genetic profiling ‘feasible’ for paediatric cancer patients

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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