DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Do long genes hold the key to understanding the genetic underpinnings of aging?

Review highlights the growing evidence that aging is linked to reduced expression of long genes, offering insights into potential anti-aging therapies based on gene length.

19 Sep 2024

Study uncovers mechanisms behind Fuchs Endothelial Corneal Dystrophy

Important insights into the mechanisms behind Fuchs Endothelial Corneal Dystrophy (FECD), a common cause of age-related visual loss, have been revealed in a new study led by UCL researchers.

19 Sep 2024

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer.

19 Sep 2024

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.

19 Sep 2024

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Asimov, the synthetic biology company advancing the design and production of therapeutics, today announced the launch of the AAV Edge System, a comprehensive suite of tools for adeno-associated viral (AAV) gene therapy design and manufacturing.

18 Sep 2024

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Researchers explore the global rise in early-onset cancers, linking environmental exposures and lifestyle changes to the surge, and advocate for tailored prevention and treatment strategies.

18 Sep 2024

Direct breastfeeding boosts microbial transfer to very-low-birth-weight infant guts

Researchers found that 30-40% of the very-low-birth-weight infant's gut microbiota came from the mother’s milk, and direct breastfeeding enhances microbial transmission despite antibiotic exposure.

18 Sep 2024

Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk

Scientists have pinpointed thousands of genetic changes in a gene that may increase a person's risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.

18 Sep 2024

Discovery of 5-formylcytosine as an activating epigenetic switch

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development.

18 Sep 2024

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing symptoms and improving outcomes.

18 Sep 2024

Genome-wide association study identifies genetic risk factors for dementia

In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing an overlap of genetic risks including neurodegeneration, vascular factors and cerebral small-vessel disease.

18 Sep 2024

A novel approach to biomolecule engineering

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins - without having to synthesize them one by one, researchers report in a new study. Using a naturally occurring process, laboratories can harness the existing molecule-building capacities of bacteria to generate vast libraries of potentially therapeutic DNA-protein hybrid molecules.

18 Sep 2024