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Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

A possible explanation has been found in a study for why apoE4, the most significant genetic risk factor associated with Alzheimer's disease, fails to protect the brain from inflammation.

25 May 2023

UQ neuroscientists uncover how vitamin D deficiency affects developing neurons in schizophrenia

Neuroscientists at The University of Queensland have uncovered how vitamin D deficiency affects developing neurons in schizophrenia, using new technology.

25 May 2023

New method can kill aggressive brain tumors

Researchers at the University of Gothenburg, working with French colleagues, have successfully developed a method able to kill the aggressive brain tumor glioblastoma.

25 May 2023

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM).

24 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

Researchers assessed the safety and efficacy of danuglipron in type 2 diabetes (T2D) patients.

24 May 2023

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

For pharmaceuticals, knowing the chemical composition is not enough - molecular geometry and crystal structure also play an important role in a drug's activity.

23 May 2023

Modified version of anti-nausea drug can enter into cells and provide long-lasting pain relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

22 May 2023

Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

AI-based method predicts small molecule substrates of enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

Combining generative AI and quantum computing to accelerate drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore lead candidate discovery in drug development and successfully demonstrated the potential advantages of quantum generative adversarial networks in generative chemistry.

19 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

Melanin structure discovery brings scientists one step closer to developing ultra-protective sunscreen

A new discovery about the structure of melanin has brought scientists one step closer to developing a new, potentially ultra-protective sunscreen derived from a biological substance found in nearly all organisms.

18 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Research discusses the activity spectrum of nourseothricin and its components, S-F and S-D, against drug-resistant, gram-negative pathogens. S-F showed promising activity against NDM-1-expressing Klebsiella pneumoniae Nevada strain with minimal toxicity, and it probes the A-decoding site potentially accounting for its miscoding activity.

17 May 2023

Molecule News and Research

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

UQ neuroscientists uncover how vitamin D deficiency affects developing neurons in schizophrenia

New method can kill aggressive brain tumors

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

Scientists study the structure and function of a transporter involved in cancer, immunity

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

Modified version of anti-nausea drug can enter into cells and provide long-lasting pain relief

Surviving without glucose: uridine-derived ribose as an alternative energy source

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

AI-based method predicts small molecule substrates of enzymes

Newly discovered molecule effectively destroys senescent cells

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

Combining generative AI and quantum computing to accelerate drug discovery

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

Melanin structure discovery brings scientists one step closer to developing ultra-protective sunscreen

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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