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Primary tumors can chose different strategies to spread and form metastases

Primary tumors can spread towards distant organs as single cells, when they lose a protein called E-cadherin.

16 May 2007

Specific genes identified that are most likely to become cancer promoters when exposed to DNA promoter hypermethylation

Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, especially for hypermethylation in breast cancer.

15 May 2007

FDA Panel warns anemia drug dangerous for cancer patients

A panel of experts advising the Food and Drug Administration (FDA) in the United States has warned that the popular anemia drug erythropoietin may not be as safe as first thought.

14 May 2007

Researchers identify human genes targeted by a virus believed to cause Kaposi's sarcoma

University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin.

11 May 2007

Oncolytic viruses deliver a knockout punch to cancers

New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers.

11 May 2007

CT and MRI are highly accurate at determining which patients would be optimal candidates for liver transplantation

CT and MRI are highly accurate at determining which patients would be optimal candidates for liver transplantation, says a recent study.

11 May 2007

Preoperative chemotherapy reduces chemo-related infections

Giving chemotherapy to women with operable breast cancer before they have surgery 'not after' helps physicians pin down the best treatment regimen and can reduce the extent of surgery, according to a new systematic review.

11 May 2007

Protein findings establish better understanding of tumor development

Peter Baumann, Ph.D., Assistant Investigator, and Nancy Bae, Ph.D., Postdoctoral Research Associate in the Baumann Lab, have published a paper offering insight into the way cells protect chromosome ends from misguided repair.

11 May 2007

Researchers discover genetic 'shut down' trigger in healthy immune cells

A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers.

10 May 2007

The financial impact of a brain tumor diagnosis on patients and families

A new study released by the National Brain Tumor Foundation, The Financial Impact of a Brain Tumor Diagnosis on Patients and Families, reveals that the financial impact for patients suffering from brain tumors is devastating and life-changing.

10 May 2007

Study implicates protein as a trigger of advanced prostate cancer recurrence

Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.

9 May 2007

Green tea may reduce the risk of skin cancer

Green tea just keeps getting better. To add to the abundance of health-improving qualities of the beverage, UAB Researcher Santosh Katiyar, Ph.D., associate professor of dermatology, claims that it can reduce the risk of skin cancer.

9 May 2007

Combined molecular-targeted and hormonal therapies offer promise in treating ovarian cancer

A combination of molecular-targeted therapy and hormonal therapy may be the most promising area of research for those seeking an effective treatment for ovarian cancer, according to a new review in the International Journal of Gynecological Cancer.

9 May 2007

Promising new target for brain tumor therapy

A drug that targets the body's immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers from Duke's Preston Robert Tisch Brain Tumor Center.

9 May 2007

Researchers create agent that protects cells from the lethal effects of radiation

No drugs exist to protect the public from the high levels of radiation that could be released by a "dirty" bomb or nuclear explosion.

9 May 2007

Abbott seeks U.S. and E.U. approvals for Humira as a treatment for juvenile rheumatoid arthritis

Abbott has announced it has simultaneously submitted a supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) and a Type II Variation to the European Medicines Agency (EMEA) seeking approval to market HUMIRA (adalimumab) as a treatment for juvenile rheumatoid arthritis (JRA) in the U.S. and juvenile idiopathic arthritis (JIA) in the European Union (EU).

9 May 2007

VCU to develop new form of radiation therapy

The National Cancer Institute has awarded a five-year, $10.7 million grant to Virginia Commonwealth University Massey Cancer Center researchers to develop a new form of radiation therapy that will enable the safe administration of more aggressive cancer treatments.

9 May 2007

Novel therapies to prevent metastasis

In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor.

8 May 2007

Discovery may lead to new treatments for lung cancer and blood cancer

The research team uses a genetically modified mouse that produces a muted and constantly active CAAX protein. This is a new model for an extremely aggressive lung cancer and a mild form of blood cancer. In these mice, the production of an enzyme called GGTas1 can also be stopped.

8 May 2007

Percutaneous radiofrequency ablation of liver tumors safe and effective

Percutaneous imaging guided radiofrequency ablation (RFA) of hepatocellular carcinoma is a safe and effective technique, with benefits such as reduced post-procedural pain and length of hospital stay, according to a study conducted by researchers from Changi General Hospital in Singapore.

8 May 2007