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Older kidney disease patients starting dialysis die at higher rates than previously thought

Older adults with end-stage kidney disease who start dialysis--a treatment that keeps their blood free of toxins--appear to die at higher rates than previously thought, according to findings of a new study by researchers at Harvard Medical School, Brigham and Women's Hospital, Veterans Affairs Boston Healthcare System and Icahn School of Medicine at Mount Sinai, among other institutions.

23 Apr 2019

Novel ECCITE-seq technique expands multimodal single cell analysis

A new technique called ECCITE-seq, developed by scientists at the New York Genome Center's Technology Innovation Lab, allows researchers to perform high-throughput measurements of multiple modalities of information from single cells.

From 10x Genomics, Inc. 23 Apr 2019

Microglia play vital role in regulating neuroinflammation, research shows

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system--including the retina of the eye--serve as "gatekeepers," or biosensors and facilitators, of neuroinflammation in a preclinical model of autoimmune uveitis.

23 Apr 2019

Reviving the heart's regenerative capacities using microRNAs

Once the heart is fully formed, the cells that make up heart muscle, known as cardiomyocytes, have very limited ability to reproduce themselves. After a heart attack, cardiomyocytes die off; unable to make new ones, the heart instead forms scar tissue. Over time, this can set people up for heart failure.

23 Apr 2019

Advance in breakthrough cancer treatment eliminates serious side effects

An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows.

22 Apr 2019

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

Many individuals forced to fight an exceptionally aggressive form of the blood cancer acute myeloid leukemia (AML) don't survive more than five years.

22 Apr 2019

Nursing, medical, and dental students train together to improve pediatric oral health

Nursing, medical, and dental students can work as a team to improve their knowledge of pediatric oral health--and how to work with their fellow health professionals, finds new research led by NYU Rory Meyers College of Nursing.

22 Apr 2019

Precision-guided anticancer nanoparticles help enhance treatment of peritoneal tumors

Research carried out at the University of Tartu Faculty of Medicine used nanoparticles for the development of new imaging and treatment methods for peritoneal cancers. Tests showed that precision-guided anticancer nanoparticles have improved efficacy and reduced side effects.

22 Apr 2019

Potential of liquid biopsy in cancer biomarker detection and prenatal testing

The promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of cancer biomarkers to enable improved and personalized therapy, is the focus of a new special issue of Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

22 Apr 2019

First-of-its-kind study highlights lethal impact of medical emergencies worldwide

Johns Hopkins Medicine researcher develops method to measure the impact of conditions requiring emergency care around the world.

22 Apr 2019

Deep-learning model better predicts survival outcomes for lung cancer

A deep-learning model developed using serial image scans of tumors from patients with non-small cell lung cancer (NSCLC) predicted treatment response and survival outcomes better than standard clinical parameters.

22 Apr 2019

Research uncovers critical RNA processing aberrations in ALS and FTD

Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontal temporal dementia was published in the April issue of Acta Neuropathologica.

21 Apr 2019

Key research takeaways from ECCMID 2019

This article aims to provide a brief overview of the key themes of the 29th ECCMID conference and update readers on current research projects.

From ESCMID 19 Apr 2019

Liver illness strikes Latino children like a ‘silent tsunami’

Saira Diaz uses her fingers to count the establishments selling fast food and sweets near the South Los Angeles home she shares with her parents and 13-year-old son. “There’s one, two, three, four, five fast-food restaurants,” she says. “And a little mom and pop store that sells snacks and sodas and candy.”

19 Apr 2019

New scoring system based on genetic markers predicts obesity risk at birth

Researchers have come up with a scoring system based on genetic markers that predicts an individual's inborn risk for obesity.

19 Apr 2019

Groundbreaking experiment in pigs challenges the notion about brain damage

The brain is more resilient than previously thought. In a groundbreaking experiment published in this week's issue of Nature, neuroscientists created an artificial circulation system that successfully restored some functions and structures in donated pig brains--up to four hours after the pigs were butchered at a USDA food processing facility.

19 Apr 2019

Revolutionary discovery paves new way for treatment of necrotizing enterocolitis

Cutting-edge discovery in the lab of Catherine Hunter, MD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago offers a new direction toward treatment of necrotizing enterocolitis - a devastating intestinal emergency that occurs in up to 10 percent of premature infants

19 Apr 2019