Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to research published today in PLOS Genetics.

11 Feb 2022

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Oregon State University scientists have discovered a new class of potential drug targets for people suffering from neurodegenerative conditions such as Alzheimer's, Parkinson's and Lou Gehrig's disease.

10 Feb 2022

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Centre have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection against Alzheimer's disease.

10 Feb 2022

KHN’s ‘What the Health?’: FDA takes center stage

The FDA is still lacking a Senate-confirmed leader, but the agency is at the center of several major policy battles. Lawmakers this year must renew the bill that authorizes drug companies to pay "user fees," which enable the agency to hire additional reviewers to speed the approval of drugs.

10 Feb 2022

Study shows link between loneliness and dementia risk in older adults

As social isolation in the United States has been increasing among older adults, a new study shows a notable link between loneliness and dementia risk, and one that is most striking for Americans who represent a large part of the population.

9 Feb 2022

Gut microbiome modulation induces behavioral, cognitive changes in Alzheimer's disease model

New research in mice for the first time draws a definitive causal connection between changes in the gut microbiome to behavioral and cognitive changes in an animal model of Alzheimer's disease.

8 Feb 2022

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

In a new study, researchers investigated a link between the body’s inflammatory response to SARS-CoV-2 infection within the neuropathological pathways and tau hyperphosphorylation.

7 Feb 2022

Researchers develop new potential method for treating Alzheimer's disease

Researchers at the faculty have developed an artificial intelligence (AI) method to help them identify potential new medicines for Alzheimer's. The new medicine seems to be more precise. No side effects were documented during tests with worms and mice.

4 Feb 2022

Scientists test a tiny biosensor to detect biomarkers linked to traumatic brain injuries

Scientists have successfully tested in the lab a tiny biosensor they developed that can detect biomarkers tied to traumatic brain injuries.

3 Feb 2022

Physical exercise increases synaptic resilience against age-related neuropathologies

Researchers from the UPV/EHU's Department of Pharmacology and the CIBER Mental Health network are taking part in a study published in the latest issue of the prestigious journal Alzheimer's & Dementia; it sheds light on the biological processes that mediate the beneficial effect of physical exercise on cognitive skills and mental health.

3 Feb 2022

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

In a new study, researchers evaluated the neurotropism of SARS-CoV-2 and its impact on COVID-19 patients with and without neurological disorders like Alzheimer's disease.

3 Feb 2022

Taking steps to prevent heart attack may help slow cognitive decline

Preventing heart attacks may help slow cognitive decline, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2022, a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health to be held in person in New Orleans, and virtually, Feb. 8-11, 2022.

3 Feb 2022

Brains of adults with heart-healthy lifestyle are larger and show fewer signs of injury, research finds

On imaging tests, brains were larger and showed fewer signs of injury in early to late middle-aged adults (ages 40-69 years) who had nearly ideal cardiovascular health, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2022, a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health to be held in person in New Orleans and virtually, Feb. 8-11, 2022.

3 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

Cognitive changes following major surgery not linked with changes in Alzheimer's-related biomarkers

Cognitive changes following non-neurologic and non-cardiac surgery were not associated with changes in Alzheimer's disease-related biomarkers in older patients, according to a study led by a team at Duke University School of Medicine.

2 Feb 2022

Non-mutated ApoE protein linked to dementia

A team of researchers from the University of Kentucky's Sanders-Brown Center on Aging is working to identify new proteins that are destructive to the brain.

2 Feb 2022

Daily physical activity boosts cognitive performance in middle-aged and older adults

A new study by researchers at University of California San Diego School of Medicine adds to the canon of research associating physical activity with cognitive performance, this time using 90 middle-aged and older subjects who wore accelerometers while physically active and completed mobile cognitive testing from home.

1 Feb 2022

Alzheimer's Disease News and Research

Further Reading

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

KHN’s ‘What the Health?’: FDA takes center stage

Study shows link between loneliness and dementia risk in older adults

Gut microbiome modulation induces behavioral, cognitive changes in Alzheimer's disease model

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

Researchers develop new potential method for treating Alzheimer's disease

Scientists test a tiny biosensor to detect biomarkers linked to traumatic brain injuries

Physical exercise increases synaptic resilience against age-related neuropathologies

Relationship between SARS-CoV-2 neurotropism and Alzheimer's disease

Taking steps to prevent heart attack may help slow cognitive decline

Brains of adults with heart-healthy lifestyle are larger and show fewer signs of injury, research finds

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Cognitive changes following major surgery not linked with changes in Alzheimer's-related biomarkers

Non-mutated ApoE protein linked to dementia

Daily physical activity boosts cognitive performance in middle-aged and older adults

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Study reveals potential mechanism for iron accumulation in the aging brain

USC’s new center aims to address unmet needs in neurodegenerative diseases of the eye and brain

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