Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Differences in DNA methylation could accurately predict progression of liver disease

Findings of a national study led by the Translational Genomics Research Institute, an affiliate of City of Hope, identify potential biomarkers that might eventually be used to diagnose progressive stages of liver disease.

20 Sep 2021

Combining antibody markers to improve serosurveillance for SARS-CoV-2

The current study found that combining N antibodies with nucleocapsid-specific IgG facilitates a better classification of SARS-CoV-2 infection.

19 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Epigenetic aging could be a promising biomarker for measuring cardiovascular disease risk

Epigenetic aging — derived from the molecular mechanisms governing gene regulation — could serve as a promising biomarker for measuring long-term cardiovascular health and disease risk, according to a Northwestern Medicine study published in the journal Circulation Research.

15 Sep 2021

Blood serum test can identify which breast cancer patients have slow-growing disease

Researchers with the SWOG Cancer Research Network have found that patients with metastatic hormone receptor-positive breast cancer who have low activity levels of the enzyme sTK1 in their blood serum at the start of anti-estrogen treatment live longer and go longer without their disease progressing than patients with high levels.

14 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Leading scientists at the University of Birmingham have discovered a previously unknown pathway that prevents specific drugs from working in patients with bowel cancer.

14 Sep 2021

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Family's socio-economic status may influence children's composition of gut microbiome

Findings of a nationwide study led by the Translational Genomics Research Institute, an affiliate of City of Hope, suggest that a family's socio-economic status may influence children's composition of gut microbiome - the mix of microscopic organisms within the digestive tract.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Study suggests 4D flow imaging as a clinical predictive tool for aortic disease

4D flow magnetic resonance imaging (MRI) has the potential to identify patients with a higher risk of severe complications from aortic degeneration according to a new Northwestern Medicine study published in JACC: Cardiovascular Imaging.

13 Sep 2021

Survey: Less than half of community oncologists use biomarker testing to guide lung cancer care

Less than half of community oncologists surveyed indicated that they use biomarker testing to guide patient discussions compared to 73% of academic clinicians, according to a report issued today at the IASLC 2021 World Conference on Lung Cancer.

12 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Measurement of brain function shows benefits of virtual reality in creative arts therapies

Virtual reality (VR) continues to expand its uses in medicine, specifically in treatments for psychological conditions like trauma, phobias and eating disorders. The technology is also emerging as a tool in creative arts therapies.

9 Sep 2021

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Despite cigarette smoking being the single most preventable risk factor for both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), two devastating diseases that make it hard to breathe, about 44 million American adults continue to smoke.

8 Sep 2021

Study suggests hospitalized COVID-19 patients have elevated Alzheimer's-related biomarkers

Neurological symptoms have been widely reported in patients with COVID-19 and in those who have recovered from it. A new study led by Thomas Wisniewski of New York University Grossman School of Medicine, USA, finds that patients hospitalized with COVID-19 are more likely to have elevated biomarkers levels indicative of age-related neurodegeneration.

8 Sep 2021

Researchers create a QIBA profile for cartilage compositional imaging

New recommendations will help provide more reliable, reproducible results for MRI-based measurements of cartilage degeneration in the knee, helping to slow down disease and prevent progression to irreversible osteoarthritis, according to a special report published in the journal Radiology.

7 Sep 2021

Owlstone Medical Closes $58 Million USD (c. £42 Million GBP) Oversubscribed Financing Round to Continue to Advance Breath Biopsy

Owlstone Medical today announced the close of its Series D financing round.

From Owlstone Medical Ltd 7 Sep 2021

Researchers find evidence that exercise during pregnancy benefits mothers and their offspring

Researchers have found further evidence that exercise during pregnancy is good not only for mothers but also for their offspring.

6 Sep 2021

Study identifies actionable genes and candidate drugs in biliary tract cancer using a knowledgebase

Oncotarget published "Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase" which reported that it is necessary to investigate actionable genes and candidate drugs using a sophisticated knowledgebase and characterize BTCs immunologically for evaluating the actionability of molecular and immune therapies.

31 Aug 2021

Biomarker News and Research

Further Reading

Differences in DNA methylation could accurately predict progression of liver disease

Combining antibody markers to improve serosurveillance for SARS-CoV-2

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Epigenetic aging could be a promising biomarker for measuring cardiovascular disease risk

Blood serum test can identify which breast cancer patients have slow-growing disease

Researchers explore whether cocoa supplementation can reduce aging

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

GIST researchers unravel coordination mechanism of base excision repair

Family's socio-economic status may influence children's composition of gut microbiome

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

Study suggests 4D flow imaging as a clinical predictive tool for aortic disease

Survey: Less than half of community oncologists use biomarker testing to guide lung cancer care

NIH researchers develop a detailed cellular map of chronic MS lesions

Measurement of brain function shows benefits of virtual reality in creative arts therapies

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Study suggests hospitalized COVID-19 patients have elevated Alzheimer's-related biomarkers

Researchers create a QIBA profile for cartilage compositional imaging

Owlstone Medical Closes $58 Million USD (c. £42 Million GBP) Oversubscribed Financing Round to Continue to Advance Breath Biopsy

Researchers find evidence that exercise during pregnancy benefits mothers and their offspring

Study identifies actionable genes and candidate drugs in biliary tract cancer using a knowledgebase

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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