Efficacy News and Research

RSS

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

Cambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impact of Alzheimer's disease.

6 Aug 2024

Nudges seem to have no effect in motivating people to get vaccinated

One popular strategy to motivate people to get vaccinated is the nudge - a message designed to take advantage of human tendencies to conform to social norms, seek to protect loved ones or community, and to prefer treatments with high efficacy rates.

6 Aug 2024

New compound ZTA-26 could be a game-changer in lipid metabolism regulation

Scientists at Nagoya University in Japan have made a significant breakthrough in treating lipid disorders.

6 Aug 2024

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target malignant cells while sparing normal tissues.

6 Aug 2024

Sugar-sweetened beverage taxes reduce child and adolescent BMI

Study reveals that city-level sugar-sweetened beverage (SSB) taxes significantly reduce body mass index (BMI) percentiles in children and adolescents. The findings support SSB taxation as a viable strategy to combat childhood obesity.

5 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

Dance therapy reduces ethnic bullying and enhances empathy in diverse students, study shows

Bullying is the most common manifestation of violence in schools. With globalization and immigration increasing classroom diversity in schools across the United States, ethnic bullying – bullying that targets another's ethnic background or cultural identity, including racial taunts/slurs and insulting references to culturally specific customs, foods, clothing, and accents and as well as exclusion from peer groups – has increased.

5 Aug 2024

PSU receives $1.9 million grant to redesign training for educators of students with disabilities

Improving outcomes for students with disabilities as they transition from high school to postsecondary education and employment starts with effective training and development opportunities for the secondary educators who support them.

5 Aug 2024

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

Chimeric antigen receptor (CAR) T–cell immunotherapy re-engineers a patient's immune cells to target cancer cells.

5 Aug 2024

Natural compound from skin bacteria shows promise as tyrosinase inhibitor for skincare

Melanin protects the skin - the body's largest organ and a vital component of the immune system - from the damaging effects of ultraviolet (UV) radiation.

5 Aug 2024

Mucosal COVID-19 vaccine prevents airborne transmission of SARS-CoV-2

The impact of mucosal versus intramuscular vaccine immunization on airborne infection and transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Syrian hamsters.

5 Aug 2024

FDA approves AChEI ALPHA-1062 for Alzheimer’s disease treatment

On July 29, 2024, the U.S. FDA approved Alpha Cognition Inc.'s ALPHA-1062 (Zunveyl®), an Acetylcholinesterase (AChE) inhibitor, for treating mild-to-moderate Alzheimer’s disease.

From Sino Biological Inc. 5 Aug 2024

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

Pioneering study brings leishmaniasis vaccine development closer

Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body's immune response, bringing a vaccine for the neglected tropical disease a step closer.

2 Aug 2024

Researchers identify strategy to design safer opioids

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose.

2 Aug 2024

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity.

1 Aug 2024

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR).

1 Aug 2024

Study reveals how geographic origins influence tuberculosis infection risk

For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a new study comparing how different strains move through mixed populations in cosmopolitan cities.

1 Aug 2024

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them.

31 Jul 2024

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

Researchers at Xiamen University have made a significant advancement in cancer treatment by developing a novel class of X-ray-sensitizers (XSs) that could revolutionize radiotherapy.

31 Jul 2024

Efficacy News and Research

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

Nudges seem to have no effect in motivating people to get vaccinated

New compound ZTA-26 could be a game-changer in lipid metabolism regulation

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Sugar-sweetened beverage taxes reduce child and adolescent BMI

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Dance therapy reduces ethnic bullying and enhances empathy in diverse students, study shows

PSU receives $1.9 million grant to redesign training for educators of students with disabilities

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

Natural compound from skin bacteria shows promise as tyrosinase inhibitor for skincare

Mucosal COVID-19 vaccine prevents airborne transmission of SARS-CoV-2

FDA approves AChEI ALPHA-1062 for Alzheimer’s disease treatment

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

Pioneering study brings leishmaniasis vaccine development closer

Researchers identify strategy to design safer opioids

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

Study reveals how geographic origins influence tuberculosis infection risk

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News