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Unlocking the power of stereochemistry to improve mRNA drug delivery

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs.

1 Aug 2025

Healing with Artificial Intelligence highlights the future of patient care

AI-based medicine will revolutionize care including for Alzheimer's and diabetes, predicts a technology expert, but it must be accessible to all patients.

1 Aug 2025

Researchers trace metabolic superpowers of hibernators to shared DNA

Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl.

1 Aug 2025

Synthetic torpor moves closer to real-world medical use

Nature is often the best model for science. For nearly a century, scientists have been trying to recreate the ability of some mammals and birds to survive extreme environmental conditions for brief or extended periods by going into torpor, when their body temperature and metabolic rate drop, allowing them to preserve energy and heat.

1 Aug 2025

Bioengineered dressing achieves rapid hemostasis and accelerated wound healing

In a study published in Advanced Materials on July 22, a team led by Dr. ZHONG Chao and Dr. AN Bolin from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, collaborating with Dr. LIU Yan from Ruijin Hospital Aﬃliated to Shanghai Jiao Tong University School of Medicine, developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.

1 Aug 2025

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and fibrosis, while chronic steatosis in turn hastens hepatic decline.

1 Aug 2025

Salk Institute's ShortStop revolutionizes genetic search

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins called microproteins.

1 Aug 2025

$5.5 million federal grant funds research to improve measurement of FXTAS treatments

UC Davis Health Professor of Psychiatry and Behavioral Sciences David Hessl will help lead a major research project to develop better ways to measure treatments for fragile X-associated tremor/ataxia syndrome (FXTAS).

31 Jul 2025

Immunocompromised people are susceptible to skin cancer caused directly by beta-HPV

Researchers at the National Institutes of Health (NIH) have shown for the first time that a type of human papillomavirus (HPV) commonly found on the skin can directly cause a form of skin cancer called cutaneous squamous cell carcinoma (cSCC) when certain immune cells malfunction.

30 Jul 2025

CPADS enables comprehensive analysis of drug resistance across 44 cancer types

CPADS integrates data from the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and the Genomics of Drug Sensitivity in Cancer (GDSC) databases, encompassing over 29,000 samples across 44 cancer types and involving 288 drugs. It provides five main analysis modules: differential expression analysis, correlation analysis, pathway analysis, drug analysis, and gene perturbation analysis.

30 Jul 2025

Single injection of gene therapy at birth may offer lasting protection against HIV

A new study in Nature shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.

30 Jul 2025

Study identifies risk factors for second colorectal cancer in people with Lynch syndrome

A current study by the German Familial Colorectal Cancer Consortium is looking at the question of which people with Lynch syndrome are at an increased risk of developing a second colorectal cancer.

30 Jul 2025

Eating meals earlier could help people at high obesity risk

Research indicates that early eating habits may lower genetic obesity risk, enhancing weight loss maintenance in at-risk adults after dietary treatments.

30 Jul 2025

Researchers classify how specific genetic mutations correspond to rare disorders

The NF-κB signaling pathway plays a pivotal role in how our bodies fight infection, heal, and regulate inflammation. At the heart of this pathway is the NEMO protein, encoded by the IKBKG gene.

30 Jul 2025

Bacteria use amyloids as molecular armor against predators

Amyloids are perhaps best known as a key driver of Alzheimer's disease.

30 Jul 2025

Innovative nanopore system enables controlled DNA unzipping

DNA holds the instructions that make us who we are. If we want to read those instructions, say to understand our predisposition to genetic disorders, we need to carefully 'unzip' DNA's iconic double-helix structure.

30 Jul 2025

Eating more ultra-processed food links depression and diabetes

New research links ultra-processed food intake to increased diabetes risk in individuals with depression, highlighting the need for healthier dietary choices.

30 Jul 2025

New method uses exosome stiffness for lung cancer gene detection

The research team led by Senior Researchers Yoonhee Lee from the Division of Biomedical Technology and Gyogwon Koo from the Division of Intelligent Robot at DGIST (under President Kunwoo Lee) has developed a technology that distinguishes lung cancer gene mutations solely by measuring the "stiffness" of exosomes-tiny particles released from cancer cells in the bloodstream-using atomic force microscopy (AFM).

30 Jul 2025

New genetic mutation linked to highly invasive Streptococcus pyogenes infections

A group of researchers led by The University of Osaka have identified a novel genetic mutation in Streptococcus pyogenes, a common bacterium which causes strep throat, significantly associated with severe invasive infections.

30 Jul 2025

Genetic profiling offers hope for understanding multiple sclerosis risk

In a major step towards early detection, University of South Australia researchers are investigating the biology behind multiple sclerosis (MS) to help predict people's genetic risk of developing the disease, long before any symptoms appear.

29 Jul 2025