Immune System News and Research

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Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL).

2 Aug 2024

CEPI and WHO call for urgent global research to prepare for the next pandemic

The Coalition for Epidemic Preparedness Innovations (CEPI) and the World Health Organization (WHO) today called on researchers and governments to strengthen and accelerate global research to prepare for the next pandemic.

2 Aug 2024

Uncovering hidden drug benefits through protein mapping

Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. For the first time, researchers at the Technical University of Munich (TUM) have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help to identify previously unknown potential benefits of existing drugs.

2 Aug 2024

Study explores interplay between bone, adrenal glands, and aging

Figuring out how the tissues in our bones, adrenal glands, muscle and fat "talk" to each other could help scientists better understand what happens to our skeletons with age, when our bones tend to lose mass and become weaker, leaving us at risk for falls and fractures.

1 Aug 2024

Discovery of potent immune cells near glioblastomas opens new avenues for treatment

Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years.

31 Jul 2024

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

31 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Study reveals IL-22BP protein's role in gut health and infection resistance

A study reported in Proceedings of the National Academy of Sciences (PNAS) shows how the presence of a specific protein called IL-22BP affects the composition of the gut microbiota and the body's response to bacterial infection.

29 Jul 2024

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers.

29 Jul 2024

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

A research team led by UC San Diego has, for the first time, shown that a wearable, non-invasive device can measure activity in human cervical nerves in clinical settings.

29 Jul 2024

Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

29 Jul 2024

Revolutionizing hepatocyte count for researchers

In this interview, NewsMedical speaks to DeNovix's Dan Schieffer about the new app developed for CellDrop, and how it aims to revolutionize hepatocyte count for the drug discovery industry, and more.

From DeNovix Inc. 29 Jul 2024

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.

25 Jul 2024

UQ opens new facility for personalized mRNA cancer vaccine development

A new facility at The University of Queensland is set to provide Australian researchers with cancer vaccines tailored to individual patients.

25 Jul 2024

Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers.

25 Jul 2024

Unveiling the healing power of Alcaligenes faecalis in diabetic wounds

There are many important reasons for keeping cuts and sores clean, but new research from the Perelman School of Medicine at the University of Pennsylvania shows that a certain bug,

25 Jul 2024

Study identifies genes increasing risk of severe COVID-19

Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers from the University Hospital Bonn (UKB) and the University of Bonn, in cooperation with other research teams from Germany, the Netherlands, Spain and Italy, investigated a particularly large group of affected individuals.

25 Jul 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

Breakthrough research identifies fibrin as key factor in preterm brain bleeds

Mark Petersen, MD, has seen firsthand the devastating effects of brain bleeds in premature babies. It's an exceedingly common condition that affects up to 20 percent of infants born before 28 weeks of gestation, bringing an increased risk for developmental delays and autism.

24 Jul 2024

WVU researchers explore immune cell interactions in multiple sclerosis

A West Virginia University immunologist is exploring how the interaction between two types of immune cells within the central nervous system covering causes multiple sclerosis to develop.

24 Jul 2024

Immune System News and Research

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CEPI and WHO call for urgent global research to prepare for the next pandemic

Uncovering hidden drug benefits through protein mapping

Study explores interplay between bone, adrenal glands, and aging

Discovery of potent immune cells near glioblastomas opens new avenues for treatment

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

ACE technology enhances single-cell protein detection with advanced signal amplification

Study reveals IL-22BP protein's role in gut health and infection resistance

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

Overcoming cancer relapse with CAR-Enhancer therapy

Revolutionizing hepatocyte count for researchers

Researchers identify a potential therapeutic target for advanced multiple sclerosis

UQ opens new facility for personalized mRNA cancer vaccine development

Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

Unveiling the healing power of Alcaligenes faecalis in diabetic wounds

Study identifies genes increasing risk of severe COVID-19

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Breakthrough research identifies fibrin as key factor in preterm brain bleeds

WVU researchers explore immune cell interactions in multiple sclerosis

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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