Inflammation News and Research

RSS

Tolebrutinib shows promise for treating non-relapsing secondary progressive multiple sclerosis

A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).

8 Apr 2025

Anxiety fuels emotional eating and weight gain, study finds

Emotional eating and body dissatisfaction mediate links between BMI changes and mental health. These psychosocial factors explain how anxiety, depression, and weight gain interrelate over time.

8 Apr 2025

Lack of ceramides in blood vessels could lead to obesity-related heart diseases

New research from Weill Cornell Medicine has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes-not the presence of certain fats, but their suppression.

8 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

New studies reveal how cytokines affect mood and behavior

Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some people experience prolonged mood swings, emotional dysregulation, and changes in behavior.

7 Apr 2025

Human dental stem cells can be transformed into excitable neuronal cells, study shows

The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of future autologous transplants.

7 Apr 2025

Breakthrough protein offers new hope for pulmonary sarcoidosis treatment

Pulmonary sarcoidosis is a lung disease characterized by granulomas-tiny clumps of immune cells that form in response to inflammation.

7 Apr 2025

Blood test breakthrough pinpoints 70 proteins linked to asthma risk in major genetic study

Researchers used UK Biobank data to identify 70 proteins with genetically predicted roles in asthma, offering insights into disease mechanisms.

7 Apr 2025

Paxlovid found ineffective for long COVID relief in new trial

Antiviral medications nirmatrelvir/ritonavir (Paxlovid) were not effective in relieving long COVID symptoms, according to a new study published in The Lancet Infectious Diseases on April 3.

7 Apr 2025

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children.

7 Apr 2025

Research uncovers root cause of gland damage in Sjögren's syndrome

Sjögren's syndrome is a chronic autoimmune disorder that affects millions worldwide, especially women, causing unrelenting dryness of the mouth and eyes.

7 Apr 2025

High-fat diet fuels cancer spread via rogue platelets

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.

7 Apr 2025

Scientists cast new light on how fasting impacts the immune system

New research from The University of Manchester may reshape our understanding of what happens to the immune system when we fast.

7 Apr 2025

Treating SIBO holistically helps patients feel better, new study finds

A 90-day real-world study in Spain shows that a comprehensive, personalized treatment for SIBO significantly improves patients’ quality of life—even when breath tests remain abnormal.

7 Apr 2025

Two-week diet swap reveals stark difference: Western vs. African heritage diets on immunity

Researchers conducted a randomized controlled trial in Tanzania to examine how switching between African heritage and Western diets affects immune and metabolic health. They found that a Western diet increases inflammation and disease risk, while heritage diets and fermented beverages like Mbege have anti-inflammatory benefits.

7 Apr 2025

Pancreatic cells show epigenetic marks before cancerous transformation

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

4 Apr 2025

Small molecular shifts can drastically alter encephalitis virus behavior

New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into a harmless bug or supercharge a relatively benign virus, influencing its ability to infect humans and cause dangerous outbreaks.

4 Apr 2025