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Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

A public-private consortium led by the biotech Iproteos -based at Parc Científic de Barcelona (PCB)-, and comprised by the biopharmaceutical company Ascil-Biopharma, the Institute for Biomedical Research (IRB Barcelona), the Centre for Genomic Regulation (CRG) and the University of the Basque Country (UPV/EHU) has launched a project to advance the development of a new neuroprotective drug for the treatment of the cognitive impairment associated with schizophrenia and other mental disorders.

31 Jan 2015

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane.

31 Jan 2015

Postprandial glucagon linked to glycaemic control in Type 1 diabetes

Research shows that postprandial glucagon levels increase over time in children with newly diagnosed Type 1 diabetes, and are associated with worsening glycaemic control, suggesting an adjunctive treatment approach.

30 Jan 2015

Researchers move one step closer to treating diabetes with human probiotic pill

Science may be one step closer to treating diabetes with a human probiotic pill, according to new Cornell University research.

30 Jan 2015

Adropin hormone offers a promising treatment option for type 2 diabetes

In a study published in Molecular Metabolism, a SLU researcher has found that adropin, a hormone that regulates whether the body burns fat or sugar during feeding and fasting cycles, can improve insulin action in obese, diabetic mice, suggesting that it may work as a therapy for type 2 diabetes.

30 Jan 2015

Plasma EGFR mutation cfDNA predicts advanced lung cancer outcome

Monitoring plasma cell-free DNA levels of epidermal growth factor receptor mutations may indicate prognosis for patients with lung adenocarcinoma after EGFR–tyrosine kinase inhibitor therapy, research suggests.

28 Jan 2015

Attaching Epirubicin drug to nanodiamonds eliminates chemoresistant cancer stem cells

A study led by the National University of Singapore found that attaching chemotherapy drug Epirubicin to nanodiamonds effectively eliminates chemoresistant cancer stem cells. The findings were first published online in ACS Nano, the official journal of the American Chemical Society, in December 2014.

26 Jan 2015

SLU researcher discovers new information about how antibiotics stop staph infections

In research published in Proceedings of the National Academy of Sciences, assistant professor of biochemistry and molecular biology at Saint Louis University Mee-Ngan F. Yap, Ph.D., discovered new information about how antibiotics like azithromycin stop staph infections, and why staph sometimes becomes resistant to drugs.

23 Jan 2015

LSU Health New Orleans researcher discovers fragment of toxic Ebola virus protein

William Gallaher, PhD, Emeritus Professor of Microbiology, Immunology & Parasitology at LSU Health New Orleans School of Medicine, has discovered a fragment of an Ebola virus protein that is toxic to cells and may contribute to infection and illness.

22 Jan 2015

Rice researchers develop new version of hydrogel to promote wound healing

Rice University scientists have found the balance necessary to aid healing with high-tech hydrogel.

21 Jan 2015

Researchers explore how M6P deficiency affects different kinds of immune cells

A group of white blood cells known as B cells, which play a key role in the human immune response, need a protein-targeting signal called mannose 6-phosphate (M6P) in order to proliferate, differentiate, and present immune cell-activating antigens, according to a study in The Journal of Cell Biology.

20 Jan 2015

QMUL researchers develop new 'microcapsule' method to treat osteoarthritis

A new 'microcapsule' treatment delivery method developed by researchers at Queen Mary University of London could reduce inflammation in cartilage affected by osteoarthritis and reverse damage to tissue. The research was funded by Arthritis Research UK and the AO Foundation.

20 Jan 2015

Study leads to discovery of rare genetic disorder

Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding the effects of this mutation, research by scientists at the RIKEN-Max Planck Joint Research Center in Japan implicates the enzyme ENGase as the factor responsible for deficient protein degradation that occurs in the absence of mouse Ngly1 gene expression.

19 Jan 2015

Knocking down a single gene can help stop stress from causing infertility, miscarriage

Scientists from the University of California Berkeley have discovered that by knocking down a single gene, they can stop stress from causing female infertility and miscarriage - in rats.

14 Jan 2015

Review shows that fish compound can help combat cardiovascular disease

A major international review of a peptide originally found in fish that could be used in the battle against cardiovascular disease has been published.

13 Jan 2015

Scientists find that blocking hormone reduces stress-induced infertility in female rats

University of California, Berkeley, scientists have discovered that chronic stress activates a hormone that reduces fertility long after the stress has ended, and that blocking this hormone returns female reproductive behavior to normal.

13 Jan 2015

EGFR mutations, ALK translocations not mutually exclusive in NSCLC

Researchers from the Republic of Korea have found that epidermal growth factor receptor mutations and anaplastic lymphoma kinase translocations can occur concomitantly in a proportion of patients with non-small-cell lung cancer.

12 Jan 2015

Virginia Tech scientists plan to design virus to switch wound-healing drug into cancer fighter

At the Virginia Tech Carilion Research Institute, three scientists are planning to create a virus capable of destroying brain cancer.

12 Jan 2015

Proteomics market expected to experience continual growth

The market for microarrays used to study the workings of proteins are in great demand, according to Kalorama Information. The healthcare market research publisher said "proteomics" instruments, reagents and testing are needed to discover new biomarkers and even new drugs, and that the market for them topped 5 billion dollars in 2013.

8 Jan 2015

Healthplex & Nutraceutical China 2015 to be held in Shanghai, China

From 24-26 June 2015, Healthplex & Nutraceutical China (HNC) will return to Shanghai, China, to serve the Asian health industry. This year, the event will take place on a larger scale, with more exhibitors and business opportunities for those in attendance.

7 Jan 2015

Peptides News and Research

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Postprandial glucagon linked to glycaemic control in Type 1 diabetes

Researchers move one step closer to treating diabetes with human probiotic pill

Adropin hormone offers a promising treatment option for type 2 diabetes

Plasma EGFR mutation cfDNA predicts advanced lung cancer outcome

Attaching Epirubicin drug to nanodiamonds eliminates chemoresistant cancer stem cells

SLU researcher discovers new information about how antibiotics stop staph infections

LSU Health New Orleans researcher discovers fragment of toxic Ebola virus protein

Rice researchers develop new version of hydrogel to promote wound healing

Researchers explore how M6P deficiency affects different kinds of immune cells

QMUL researchers develop new 'microcapsule' method to treat osteoarthritis

Study leads to discovery of rare genetic disorder

Knocking down a single gene can help stop stress from causing infertility, miscarriage

Review shows that fish compound can help combat cardiovascular disease

Scientists find that blocking hormone reduces stress-induced infertility in female rats

EGFR mutations, ALK translocations not mutually exclusive in NSCLC

Virginia Tech scientists plan to design virus to switch wound-healing drug into cancer fighter

Proteomics market expected to experience continual growth

Healthplex & Nutraceutical China 2015 to be held in Shanghai, China

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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