Preclinical News and Research

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SARS-CoV-2 infection could increase the risk of brain degeneration seen in Parkinson's disease

Brain fog, headaches, insomnia are some of the neurological symptoms doctors have observed in COVID-19 patients.

18 May 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

18 May 2022

Treatment with imatinib results in lower mortality rates for patients with severe COVID-19

Patients with severe COVID-19 who were given imatinib had lower mortality rates at 90-day follow-up, according to research published at the ATS 2022 international conference.

18 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Cannabidiol for Parkinson's disease symptom management

Scientists have published a review study in the Journal for Nurse Practitioners that has focussed on various aspects of the use of cannabidiol in Parkinson's.

17 May 2022

Invasive breast cancer risk in men may be linked to self-reported infertility

The risk of invasive breast cancer in men may be associated with self-reported infertility in the male partner finds a study published in the open-access journal Breast Cancer Research.

17 May 2022

New imaging probe illuminates breast cancer cells to optimize tumor removal

Nearly 13 percent of women born in the U.S. today will develop breast cancer at some point during their lives.

16 May 2022

Allergic asthma, allergies may be associated with the risk of cardiovascular diseases

When most people think of cardiovascular diseases (CVD), risk factors such as high blood pressure, high cholesterol, obesity, and diabetes likely come to mind.

16 May 2022

Novel approach allows islet transplants to survive and control diabetes

In type 1 diabetes, an autoimmune response attacks the pancreas's insulin-producing beta cells, leading to marked fluctuations in blood sugar levels. Lifelong daily insulin treatments are standard for patients, but replacing lost beta cells through transplants of islets, a group of cells in the pancreas, represents an attractive option.

13 May 2022

Topical drugs may regress congenital giant nevi and prevent skin cancer

About one in 20,000 infants is born with what's called a congenital giant nevus - a huge, pigmented mole that may cover much of the face and body.

12 May 2022

Study could provide a new approach to treating metastatic triple negative breast cancer

Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer.

12 May 2022

Deep learning technology boosts the speed of localization photoacoustic imaging

After a lightning strike, thunder can be heard for a short period of time afterward. This is due to the fact that the surrounding material that was struck by lightning absorbs the light, and as a result of the conversion of this light into heat, the material expands and produces a sound.

12 May 2022

New MRI nanotechnology designed to precisely image aggressive brain tumors

A novel technology designed to precisely image aggressive brain cancers and guide treatment is being developed by the University of South Australia and Australian cancer diagnostic company, Ferronova, potentially helping thousands of people who are diagnosed with the deadly condition each year.

12 May 2022

Phase 1 trial of COVID-19 PTXCOVID19-B vaccine

A new study demonstrated that the SARS-CoV-2 PTXCOVID19-B vaccine was a promising SARS-CoV-2 vaccine option.

12 May 2022

World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

UVA Health and the Charlottesville-based Focused Ultrasound Foundation today announced the launch of the Focused Ultrasound Cancer Immunotherapy Center, the world's first center dedicated specifically to advancing a focused ultrasound and cancer immunotherapy treatment approach that could revolutionize 21st-century cancer care.

11 May 2022

New initiative focuses on patients with the rarest of gene mutations to develop personalized ALS therapies

A new initiative, Silence ALS, will develop experimental personalized therapies to treat patients with rare genetic forms of ALS (also known as Lou Gehrig's disease).

10 May 2022

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

9 May 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A new study published in the New England Journal of Medicine has discussed the efficacy and safety profile of the ZF2001 vaccine in adults, based on a randomized, placebo-controlled, multinational, double-blind phase 3 trial.

9 May 2022

Preclinical News and Research

SARS-CoV-2 infection could increase the risk of brain degeneration seen in Parkinson's disease

Recombinant protein vaccine stands up to SARS-CoV-2 variants

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

Treatment with imatinib results in lower mortality rates for patients with severe COVID-19

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Cannabidiol for Parkinson's disease symptom management

Invasive breast cancer risk in men may be linked to self-reported infertility

New imaging probe illuminates breast cancer cells to optimize tumor removal

Allergic asthma, allergies may be associated with the risk of cardiovascular diseases

Novel approach allows islet transplants to survive and control diabetes

Topical drugs may regress congenital giant nevi and prevent skin cancer

Study could provide a new approach to treating metastatic triple negative breast cancer

Deep learning technology boosts the speed of localization photoacoustic imaging

New MRI nanotechnology designed to precisely image aggressive brain tumors

Phase 1 trial of COVID-19 PTXCOVID19-B vaccine

World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

New initiative focuses on patients with the rarest of gene mutations to develop personalized ALS therapies

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

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