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New combination approach to eradicate established tumors

A laboratory study conducted at Leiden University Medical Center in the Netherlands has found that immunotherapy can be efficiently combined with photodynamic therapy (PDT) to eradicate established tumors. The approach results in strong local tumor destruction and a robust systemic immune response against the disease.

27 Nov 2015

Cognitive behavioural therapy benefits people with dental phobia

Cognitive behavioural therapy could help many people with a dental phobia overcome their fear of visiting the dentist and enable them to receive dental treatment without the need to be sedated, according to a new study by King's College London.

27 Nov 2015

Researchers reveal new technique to grow human hepatocytes in the laboratory

In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

27 Nov 2015

Progesterone supplements fail to improve birth rate among women with a history of miscarriage

A new study has shown that taking progesterone supplements during the first trimester of pregnancy does not improve the chances of maintaining pregnancy among women who have a history of unexplained recurrent miscarriage.

26 Nov 2015

Medical professionals compare different treatment options for Neuromyelitis optica

In the course of a study conducted throughout Germany, medical professionals have compared different treatment methods for Neuromyelitis optica, an inflammatory disease of the central nervous system. It turned out that the best results were not achieved with conventional steroid therapy.

26 Nov 2015

New drug combination shows promise in treating men with metastatic prostate cancer

A new drug combination may be effective in treating men with metastatic prostate cancer. Preliminary results of this new approach are encouraging and have led to an ongoing international study being conducted in 196 hospitals worldwide.

26 Nov 2015

Study: Mother Nature may help lower cholesterol levels in pregnant women

When it comes to effective solutions for lowering cholesterol levels in pregnant women, Mother Nature may know best.

26 Nov 2015

Research reveals MECP2 Duplication Syndrome can be reversed

The methyl CpG binding protein 2 gene (MECP2) produces a protein of the same name, the level of which is critical for normal brain function. Mutations leading to protein under-expression cause Rett Syndrome while gene duplication causing over-expression lead to MECP2 Duplication Syndrome. Both disorders are severely debilitating childhood neurological diseases.

26 Nov 2015

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. Researchers from the University and University Hospital Basel have now for the first time successfully combined such an antibody-drug conjugate with a therapy that stimulates the immune system to attack tumor cells.

26 Nov 2015

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Investigators at Montreal's Lady Davis Institute at the Jewish General Hospital and McGill University Health Centre have announced the start of a landmark clinical study aimed at restoring normal insulin secretion in people with longstanding type 1 diabetes.

26 Nov 2015

TransLUMINAL-B project kicked off to study luminal breast cancers

Following a kick-off meeting, the TransLUMINAL-B project, which is being led by Charité -- Universitätsmedizin Berlin, is now officially underway. Over the next three years, researchers involved in the project will study the process of metastasis formation and the role of malignant cells, which accumulate in the blood and bone marrow of patients with certain types of breast cancer.

26 Nov 2015

New drug may show promise against resistant melanomas

A new drug discovered by scientists at Sanford Burnham Prebys Medical Discovery Institute may show promise for treating skin cancers that are resistant or unresponsive to today's leading therapies.

25 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Mathematical models may help to predict risk of cancer spread following surgery

The size of a surgically removed tumor is generally thought to relate to the risk of the cancer spreading to other regions of the body. But because tumor cells may metastasize at different times and the rate of spread is difficult to assess, the relationship between tumor size and the relative risk of recurrence after surgery is challenging to calculate.

25 Nov 2015

RPCI-led researchers identify strategies to prevent acute kidney injury

Acute kidney injury (AKI), also known as acute renal failure, is one of the main contributors to death and disability worldwide, yet no preventive treatment for the condition has been established. In a new study published in the journal Cell Death and Differentiation, a team of researchers led by scientists from Roswell Park Cancer Institute reports that they have identified 10 genes whose inhibition appears to protect kidney cells.

25 Nov 2015

Ultrasound can help identify patients at increased risk of future stroke

Ultrasound, a non-invasive technique commonly used to study the presence of atherosclerosis disease in blood vessels, can be used to identify patients at increased risk of future stroke who could benefit from surgery. Since surgical treatment to prevent stroke is only considered beneficial to some, ultrasound can prove useful in preventing unnecessary surgical intervention, new research at Umeå University in Sweden shows.

25 Nov 2015

Risk of developing visceral leishmaniasis much higher in transplant patients

Researchers from Spain have analysed the prevalence of leishmaniasis among the population of organ transplant recipients. The findings of this study, published in the journal 'PLoS Neglected Tropical Disease', confirm that the risk of developing visceral leishmaniasis ‑the most severe form of the disease which can pose life-threatening complications‑ is more than one hundred times greater in transplant patients living in areas of disease outbreak.

25 Nov 2015

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Schizophrenia, a severe mental disorder affecting about one in 100 people, is notoriously difficult to diagnose and treat, in large part because it manifests differently in different people. A new study published today in Molecular Neuropsychiatry helps explain why.

25 Nov 2015

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Scientists from the University of Leicester have for the first time created a detailed image of a toxin - called pneumolysin - associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia.

25 Nov 2015

Therapeutic hypothermia after cardiac arrest improves survival and neurological outcomes

Survivors of cardiac arrest who remain in comas have better survival and neurological outcomes when their body temperatures are lowered, according to new research by Dr. Sarah Perman at the University of Colorado Anschutz Medical Campus.

25 Nov 2015

Therapy News and Research

New combination approach to eradicate established tumors

Cognitive behavioural therapy benefits people with dental phobia

Researchers reveal new technique to grow human hepatocytes in the laboratory

Progesterone supplements fail to improve birth rate among women with a history of miscarriage

Medical professionals compare different treatment options for Neuromyelitis optica

New drug combination shows promise in treating men with metastatic prostate cancer

Study: Mother Nature may help lower cholesterol levels in pregnant women

Research reveals MECP2 Duplication Syndrome can be reversed

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

TransLUMINAL-B project kicked off to study luminal breast cancers

New drug may show promise against resistant melanomas

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Mathematical models may help to predict risk of cancer spread following surgery

RPCI-led researchers identify strategies to prevent acute kidney injury

Ultrasound can help identify patients at increased risk of future stroke

Risk of developing visceral leishmaniasis much higher in transplant patients

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Scientists create detailed image of deadly toxin linked to bacterial pneumonia, meningitis, septicaemia

Therapeutic hypothermia after cardiac arrest improves survival and neurological outcomes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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