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IQWiG examines added benefit of tiotropium and olodaterol combination in adults with COPD

The fixed-dose combination of tiotropium and olodaterol (trade name: Spiolto Respimat) has been approved since July 2015 for maintenance treatment in adults with chronic obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug combination offers an added benefit over the appropriate comparator therapy.

22 Nov 2015

Crucial tumor-suppressing gene protects immune attack against lung cancer

A crucial tumor-thwarting gene protects an immune attack against lung cancer by blocking the key to an off switch on T cells, the customized warriors of the immune system, a team led by researchers at The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

21 Nov 2015

Mason researchers patent new breast cancer treatment

George Mason University researchers have patented a new breast cancer treatment that uses a common malaria drug to stop cancer in its beginning stages.

21 Nov 2015

Researchers receive $6 million to further develop potential treatment for cocaine abuse

University of Kentucky College of Pharmacy Professor Chang-Guo Zhan, along with fellow UK Professors Fang Zheng and Sharon Walsh, and Professor Mei-Chuan Ko from Wake Forest University, recently received $6 million in funding over five years to further develop a potential treatment for cocaine abuse.

21 Nov 2015

AfBPM's second National Summit aims to improve pain management, patient safety

The Alliance for Balanced Pain Management, a diverse collective of 24 health care advocacy groups, patient organizations, industry representatives and other stakeholders, held its second National Summit on Nov. 12 and 13, 2015, to identify continued ways to support appropriate access to integrated pain management and responsible use of prescription pain medicines with an aim to improve patient safety and reduce abuse.

21 Nov 2015

TVA Medical announces results from multicenter clinical study of everlinQ endoAVF System

TVA Medical, Inc., announced clinical trial results from a prospective, multicenter clinical study evaluating the everlinQ endoAVF System. This innovative medical technology creates hemodialysis access using vascular sites not traditionally used by surgeons for people with end-stage kidney disease (ESKD).

21 Nov 2015

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Ninlaro (ixazomib) in combination with two other therapies to treat people with multiple myeloma who have received at least one prior therapy.

21 Nov 2015

‘More is better’ for medical management of acute stroke

The outcomes of stroke patients assigned to receive medical therapy in the SAMMPRIS trial were significantly influenced by the experience of the centre in which they were treated, research shows.

20 Nov 2015

New data shows ALS-008176 drug safe and effective against RSV infection

Alios BioPharma, Inc., part of the Janssen Pharmaceutical Companies announced that the New England Journal of Medicine will publish findings from a respiratory syncytial virus (RSV) challenge study for ALS-008176, a cytidine nucleoside analog with activity against RSV.

20 Nov 2015

12 months of liquid formula HIV drugs protect breastfeeding babies against HIV infection

A study from four countries in Africa, published in The Lancet, shows that providing babies with up to 12 months of liquid formula HIV drugs, while breastfeeding with their HIV-positive mothers, is highly effective at protecting them from infection, including in the 6–12 month period after birth which has not been analysed in previous research.

20 Nov 2015

NICE recommends Xofigo (radium-223 dichloride) for patients with advanced prostate cancer

The National Institute for Health and Care Excellence today issued its Final Appraisal Determination (FAD) recommending Xofigo (radium-223 dichloride) for use on the NHS in England as an option for treating adult men, with hormone-relapsed prostate cancer, symptomatic bone metastases and no known visceral metastases, who have received previous docetaxel therapy.

20 Nov 2015

New injectable 'biogel' may become new weapon against cancer

A new injectable "biogel" is effective in delivering anti-cancer agents directly into cancerous tumours and killing them. This technology, developed by researchers at the University of Montreal Hospital Research Centre, has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionize treatment for many forms of cancer.

20 Nov 2015

New study reveals better treatment options for proliferative diabetic retinopathy

This National Diabetes Month, there is some good news for people with eye complications from diabetes. Earlier this month, a network of researchers supported by the National Eye Institute (NEI) found that the drug Lucentis (ranibizumab) can be highly effective for treating proliferative diabetic retinopathy, an eye disease that can occur as a complication of diabetes.

20 Nov 2015

Sickle cell disease treatment may help protect kidney function in patients

A drug used to treat sickle cell disease may provide an added benefit of protecting patients' kidney function, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

20 Nov 2015

WSU researchers establish categorical distinction between heterosexuals and non-heterosexuals

Washington State University researchers have established a categorical distinction between people who are heterosexual and those who are not. By analyzing the reported sexual behavior, identity and attraction of more than 33,000 American adults, they found that 3 percent of men and 2.7 percent of women are not heterosexual. They also found notable issues on several mental health fronts.

20 Nov 2015

New nanocarriers may effectively deliver therapeutic drug to GBM tumors

Glioblastoma multiforme, a cancer of the brain also known as "octopus tumors" because of the manner in which the cancer cells extend their tendrils into surrounding tissue, is virtually inoperable, resistant to therapies, and always fatal, usually within 15 months of onset.

20 Nov 2015

Urine-derived iPSCs model could help predict patient response to cholesterol-lowering drugs

We all know how important it is to keep our levels of blood cholesterol - especially the 'bad' variety - in check with a healthy diet and regular exercise. Although cholesterol is a key structural component of cell membranes and is vital for the biosynthesis of certain hormones and vitamins, high levels can lead to the formation of arterial plaques, which are a major risk factor for coronary heart disease.

20 Nov 2015

Scientists identify way to sensitize drug-resistant glioblastoma cells to chemotherapy

Scientists from the Virginia Tech Carilion Research Institute and clinicians from Carilion Clinic have discovered how to sensitize drug-resistant human glioblastoma cells to chemotherapy.

20 Nov 2015

Lilly, Merck expand oncology clinical trial collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced the extension of an existing collaboration to evaluate the safety and efficacy of the combination of Lilly's ALIMTA (pemetrexed for injection) and Merck's KEYTRUDA (pembrolizumab) in a pivotal Phase III study in first-line nonsquamous non-small cell lung cancer (NSCLC).

19 Nov 2015

New drug combination may reduce need for complex regimens to treat hepatitis C

The prognosis for people with hepatitis C has improved dramatically in the last few years, thanks to the introduction of direct-acting anti-viral medications, including Harvoni (the brand name for a combination of ledipasvir and sofosbuvir) and Viekira Pack (a mix of ombitasvir, paritaprevir, ritonavir and dasabuvir).

19 Nov 2015

Therapy News and Research

IQWiG examines added benefit of tiotropium and olodaterol combination in adults with COPD

Crucial tumor-suppressing gene protects immune attack against lung cancer

Mason researchers patent new breast cancer treatment

Researchers receive $6 million to further develop potential treatment for cocaine abuse

AfBPM's second National Summit aims to improve pain management, patient safety

TVA Medical announces results from multicenter clinical study of everlinQ endoAVF System

Ninlaro (ixazomib) approved to treat people with multiple myeloma

‘More is better’ for medical management of acute stroke

New data shows ALS-008176 drug safe and effective against RSV infection

12 months of liquid formula HIV drugs protect breastfeeding babies against HIV infection

NICE recommends Xofigo (radium-223 dichloride) for patients with advanced prostate cancer

New injectable 'biogel' may become new weapon against cancer

New study reveals better treatment options for proliferative diabetic retinopathy

Sickle cell disease treatment may help protect kidney function in patients

WSU researchers establish categorical distinction between heterosexuals and non-heterosexuals

New nanocarriers may effectively deliver therapeutic drug to GBM tumors

Urine-derived iPSCs model could help predict patient response to cholesterol-lowering drugs

Scientists identify way to sensitize drug-resistant glioblastoma cells to chemotherapy

Lilly, Merck expand oncology clinical trial collaboration

New drug combination may reduce need for complex regimens to treat hepatitis C

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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